Reactome | Ghost homologue of PSMB4 [nucleoplasm]

Cell Cycle (Xenopus tropicalis)

- Cell Cycle Checkpoints (Xenopus tropicalis)
  - G1/S DNA Damage Checkpoints (Xenopus tropicalis)
    - p53-Independent G1/S DNA Damage Checkpoint (Xenopus tropicalis)
      - Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A (Xenopus tropicalis)
        
        Proteolytic degradation of ubiquitinated-Cdc25A (Xenopus tropicalis)
        
        26S proteasome [nucleoplasm] (Xenopus tropicalis)
        
        20S core particle [nucleoplasm] (Xenopus tropicalis)
        
        20S CP inner ring [nucleoplasm] (Xenopus tropicalis)
        
        Ghost homologue of PSMB4 [nucleoplasm] (Xenopus tropicalis)
- Cell Cycle, Mitotic (Xenopus tropicalis)
  - Regulation of mitotic cell cycle (Xenopus tropicalis)
    - APC/C-mediated degradation of cell cycle proteins (Xenopus tropicalis)
      - APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 (Xenopus tropicalis)
        
        APC/C:Cdh1-mediated degradation of Skp2 (Xenopus tropicalis)
        
        26S proteasome [nucleoplasm] (Xenopus tropicalis)
        
        20S core particle [nucleoplasm] (Xenopus tropicalis)
        
        20S CP inner ring [nucleoplasm] (Xenopus tropicalis)
        
        Ghost homologue of PSMB4 [nucleoplasm] (Xenopus tropicalis)
      - Autodegradation of Cdh1 by Cdh1:APC/C (Xenopus tropicalis)
        
        Degradation of multiubiquitinated Cdh1 (Xenopus tropicalis)
        
        26S proteasome [nucleoplasm] (Xenopus tropicalis)
        
        20S core particle [nucleoplasm] (Xenopus tropicalis)
        
        20S CP inner ring [nucleoplasm] (Xenopus tropicalis)
        
        Ghost homologue of PSMB4 [nucleoplasm] (Xenopus tropicalis)

Cellular responses to stimuli (Xenopus tropicalis)

- Cellular responses to stress (Xenopus tropicalis)
  - Cellular response to chemical stress (Xenopus tropicalis)
    - KEAP1-NFE2L2 pathway (Xenopus tropicalis)
      - Nuclear events mediated by NFE2L2 (Xenopus tropicalis)
        
        GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 (Xenopus tropicalis)
        
        Ub,pS335,S338,T NFE2L2 is degraded (Xenopus tropicalis)
        
        26S proteasome [nucleoplasm] (Xenopus tropicalis)
        
        20S core particle [nucleoplasm] (Xenopus tropicalis)
        
        20S CP inner ring [nucleoplasm] (Xenopus tropicalis)
        
        Ghost homologue of PSMB4 [nucleoplasm] (Xenopus tropicalis)

DNA Replication (Xenopus tropicalis)

- DNA Replication Pre-Initiation (Xenopus tropicalis)
  - Assembly of the pre-replicative complex (Xenopus tropicalis)
    - Ubiquitinated geminin is degraded by the proteasome (Xenopus tropicalis)
      - 26S proteasome [nucleoplasm] (Xenopus tropicalis)
        
        20S core particle [nucleoplasm] (Xenopus tropicalis)
        
        20S CP inner ring [nucleoplasm] (Xenopus tropicalis)
        
        Ghost homologue of PSMB4 [nucleoplasm] (Xenopus tropicalis)

Gene expression (Transcription) (Xenopus tropicalis)

- RNA Polymerase II Transcription (Xenopus tropicalis)
  - Generic Transcription Pathway (Xenopus tropicalis)
    - Transcriptional regulation by RUNX2 (Xenopus tropicalis)
      - Regulation of RUNX2 expression and activity (Xenopus tropicalis)
        
        26S proteasome degrades PolyUb-RUNX2 (Xenopus tropicalis)
        
        26S proteasome [nucleoplasm] (Xenopus tropicalis)
        
        20S core particle [nucleoplasm] (Xenopus tropicalis)
        
        20S CP inner ring [nucleoplasm] (Xenopus tropicalis)
        
        Ghost homologue of PSMB4 [nucleoplasm] (Xenopus tropicalis)
    - Transcriptional regulation by RUNX3 (Xenopus tropicalis)
      - Regulation of RUNX3 expression and activity (Xenopus tropicalis)
        
        Polyubiquitinated RUNX3 is degraded by the proteasome (Xenopus tropicalis)
        
        26S proteasome [nucleoplasm] (Xenopus tropicalis)
        
        20S core particle [nucleoplasm] (Xenopus tropicalis)
        
        20S CP inner ring [nucleoplasm] (Xenopus tropicalis)
        
        Ghost homologue of PSMB4 [nucleoplasm] (Xenopus tropicalis)

Signal Transduction (Xenopus tropicalis)

- Signaling by Hedgehog (Xenopus tropicalis)
  - Hedgehog 'on' state (Xenopus tropicalis)
    - GLI2,3 are degraded by the proteasome (Xenopus tropicalis)
      - 26S proteasome [nucleoplasm] (Xenopus tropicalis)
        
        20S core particle [nucleoplasm] (Xenopus tropicalis)
        
        20S CP inner ring [nucleoplasm] (Xenopus tropicalis)
        
        Ghost homologue of PSMB4 [nucleoplasm] (Xenopus tropicalis)