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phospho-p-S257,T261-MAP2K4 [cytosol]
Stable Identifier
R-XTR-168170
Type
Protein [EntityWithAccessionedSequence]
Species
Xenopus tropicalis
Compartment
cytosol
Synonyms
A9UM81
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Xenopus tropicalis)
Cellular responses to stress (Xenopus tropicalis)
Cellular Senescence (Xenopus tropicalis)
Oxidative Stress Induced Senescence (Xenopus tropicalis)
Phosphorylation of human JNKs by activated MKK4/MKK7 (Xenopus tropicalis)
phospho-p-S257,T261-MAP2K4 [cytosol] (Xenopus tropicalis)
Immune System (Xenopus tropicalis)
Cytokine Signaling in Immune system (Xenopus tropicalis)
Signaling by Interleukins (Xenopus tropicalis)
Interleukin-17 signaling (Xenopus tropicalis)
MAP kinase activation (Xenopus tropicalis)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Xenopus tropicalis)
Activated TAK1 phosphorylates MKK4/MKK7 (Xenopus tropicalis)
phospho-p-S257,T261-MAP2K4 [cytosol] (Xenopus tropicalis)
Phosphorylation of human JNKs by activated MKK4/MKK7 (Xenopus tropicalis)
phospho-p-S257,T261-MAP2K4 [cytosol] (Xenopus tropicalis)
Innate Immune System (Xenopus tropicalis)
Fc epsilon receptor (FCERI) signaling (Xenopus tropicalis)
FCERI mediated MAPK activation (Xenopus tropicalis)
Phosphorylation of MEK4 by MEKK1 (Xenopus tropicalis)
phospho-p-S257,T261-MAP2K4 [cytosol] (Xenopus tropicalis)
Phosphorylation of human JNKs by activated MKK4/MKK7 (Xenopus tropicalis)
phospho-p-S257,T261-MAP2K4 [cytosol] (Xenopus tropicalis)
Toll-like Receptor Cascades (Xenopus tropicalis)
Toll Like Receptor 10 (TLR10) Cascade (Xenopus tropicalis)
MyD88 cascade initiated on plasma membrane (Xenopus tropicalis)
MAP kinase activation (Xenopus tropicalis)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Xenopus tropicalis)
Activated TAK1 phosphorylates MKK4/MKK7 (Xenopus tropicalis)
phospho-p-S257,T261-MAP2K4 [cytosol] (Xenopus tropicalis)
Phosphorylation of human JNKs by activated MKK4/MKK7 (Xenopus tropicalis)
phospho-p-S257,T261-MAP2K4 [cytosol] (Xenopus tropicalis)
Toll Like Receptor 2 (TLR2) Cascade (Xenopus tropicalis)
Toll Like Receptor TLR1:TLR2 Cascade (Xenopus tropicalis)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Xenopus tropicalis)
MAP kinase activation (Xenopus tropicalis)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Xenopus tropicalis)
Activated TAK1 phosphorylates MKK4/MKK7 (Xenopus tropicalis)
phospho-p-S257,T261-MAP2K4 [cytosol] (Xenopus tropicalis)
Phosphorylation of human JNKs by activated MKK4/MKK7 (Xenopus tropicalis)
phospho-p-S257,T261-MAP2K4 [cytosol] (Xenopus tropicalis)
Toll Like Receptor TLR6:TLR2 Cascade (Xenopus tropicalis)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Xenopus tropicalis)
MAP kinase activation (Xenopus tropicalis)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Xenopus tropicalis)
Activated TAK1 phosphorylates MKK4/MKK7 (Xenopus tropicalis)
phospho-p-S257,T261-MAP2K4 [cytosol] (Xenopus tropicalis)
Phosphorylation of human JNKs by activated MKK4/MKK7 (Xenopus tropicalis)
phospho-p-S257,T261-MAP2K4 [cytosol] (Xenopus tropicalis)
Toll Like Receptor 3 (TLR3) Cascade (Xenopus tropicalis)
MAP kinase activation (Xenopus tropicalis)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Xenopus tropicalis)
Activated TAK1 phosphorylates MKK4/MKK7 (Xenopus tropicalis)
phospho-p-S257,T261-MAP2K4 [cytosol] (Xenopus tropicalis)
Phosphorylation of human JNKs by activated MKK4/MKK7 (Xenopus tropicalis)
phospho-p-S257,T261-MAP2K4 [cytosol] (Xenopus tropicalis)
Toll Like Receptor 4 (TLR4) Cascade (Xenopus tropicalis)
MyD88-independent TLR4 cascade (Xenopus tropicalis)
TRIF (TICAM1)-mediated TLR4 signaling (Xenopus tropicalis)
MAP kinase activation (Xenopus tropicalis)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Xenopus tropicalis)
Activated TAK1 phosphorylates MKK4/MKK7 (Xenopus tropicalis)
phospho-p-S257,T261-MAP2K4 [cytosol] (Xenopus tropicalis)
Phosphorylation of human JNKs by activated MKK4/MKK7 (Xenopus tropicalis)
phospho-p-S257,T261-MAP2K4 [cytosol] (Xenopus tropicalis)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Xenopus tropicalis)
MAP kinase activation (Xenopus tropicalis)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Xenopus tropicalis)
Activated TAK1 phosphorylates MKK4/MKK7 (Xenopus tropicalis)
phospho-p-S257,T261-MAP2K4 [cytosol] (Xenopus tropicalis)
Phosphorylation of human JNKs by activated MKK4/MKK7 (Xenopus tropicalis)
phospho-p-S257,T261-MAP2K4 [cytosol] (Xenopus tropicalis)
Toll Like Receptor 5 (TLR5) Cascade (Xenopus tropicalis)
MyD88 cascade initiated on plasma membrane (Xenopus tropicalis)
MAP kinase activation (Xenopus tropicalis)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Xenopus tropicalis)
Activated TAK1 phosphorylates MKK4/MKK7 (Xenopus tropicalis)
phospho-p-S257,T261-MAP2K4 [cytosol] (Xenopus tropicalis)
Phosphorylation of human JNKs by activated MKK4/MKK7 (Xenopus tropicalis)
phospho-p-S257,T261-MAP2K4 [cytosol] (Xenopus tropicalis)
Toll Like Receptor 7/8 (TLR7/8) Cascade (Xenopus tropicalis)
MyD88 dependent cascade initiated on endosome (Xenopus tropicalis)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Xenopus tropicalis)
MAP kinase activation (Xenopus tropicalis)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Xenopus tropicalis)
Activated TAK1 phosphorylates MKK4/MKK7 (Xenopus tropicalis)
phospho-p-S257,T261-MAP2K4 [cytosol] (Xenopus tropicalis)
Phosphorylation of human JNKs by activated MKK4/MKK7 (Xenopus tropicalis)
phospho-p-S257,T261-MAP2K4 [cytosol] (Xenopus tropicalis)
Toll Like Receptor 9 (TLR9) Cascade (Xenopus tropicalis)
MyD88 dependent cascade initiated on endosome (Xenopus tropicalis)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Xenopus tropicalis)
MAP kinase activation (Xenopus tropicalis)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Xenopus tropicalis)
Activated TAK1 phosphorylates MKK4/MKK7 (Xenopus tropicalis)
phospho-p-S257,T261-MAP2K4 [cytosol] (Xenopus tropicalis)
Phosphorylation of human JNKs by activated MKK4/MKK7 (Xenopus tropicalis)
phospho-p-S257,T261-MAP2K4 [cytosol] (Xenopus tropicalis)
External Reference Information
External Reference
UniProt:A9UM81
Reference Genes
BioGPS Gene:100135013
ENSEMBL:ENSXETG00000011036
KEGG:xtr:100135013
Monarch:100135013
NCBI Gene:100135013
UCSC:A9UM81
Reference Transcript
RefSeq:NM_001113685.1
Participates
as an output of
Phosphorylation of MEK4 by MEKK1 (Xenopus tropicalis)
Activated TAK1 phosphorylates MKK4/MKK7 (Xenopus tropicalis)
Other forms of this molecule
MAP2K4 [cytosol]
Inferred From
p-MAP2K4/p-MAP2K7 [cytosol]
(Homo sapiens)
p-S257,T261-MAP2K4 [cytosol]
(Homo sapiens)
Modified Residues
Name
O-phospho-L-serine at 257 (in Homo sapiens)
Coordinate
257
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-threonine at 261 (in Homo sapiens)
Coordinate
261
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Cross References
RefSeq
NP_001107157.1
Xenbase
XB-GENE-482151
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