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phospho-p-Y1056,Y1188,Y1242-ERBB4 JM-A CYT-1 isoform [plasma membrane]
Stable Identifier
R-XTR-1250319
Type
Protein [EntityWithAccessionedSequence]
Species
Xenopus tropicalis
Compartment
plasma membrane
Synonyms
A0A6I8R0X7
Locations in the PathwayBrowser
Expand all
Signal Transduction (Xenopus tropicalis)
Intracellular signaling by second messengers (Xenopus tropicalis)
PIP3 activates AKT signaling (Xenopus tropicalis)
Negative regulation of the PI3K/AKT network (Xenopus tropicalis)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Xenopus tropicalis)
PI3K phosphorylates PIP2 to PIP3 (Xenopus tropicalis)
Activator:PI3K [plasma membrane] (Xenopus tropicalis)
PI3K:p-ERBB4cyt1 [plasma membrane] (Xenopus tropicalis)
p-ERBB4cyt1 homodimers [plasma membrane] (Xenopus tropicalis)
p-ERBB4jmAcyt1 [plasma membrane] (Xenopus tropicalis)
NRGs/EGF-like ligands:P-ERBB4jmAcyt1 [plasma membrane] (Xenopus tropicalis)
phospho-p-Y1056,Y1188,Y1242-ERBB4 JM-A CYT-1 isoform [plasma membrane] (Xenopus tropicalis)
PI3K phosphorylates PIP2 to PIP3 (Xenopus tropicalis)
Activator:PI3K [plasma membrane] (Xenopus tropicalis)
PI3K:p-ERBB4cyt1 [plasma membrane] (Xenopus tropicalis)
p-ERBB4cyt1 homodimers [plasma membrane] (Xenopus tropicalis)
p-ERBB4jmAcyt1 [plasma membrane] (Xenopus tropicalis)
NRGs/EGF-like ligands:P-ERBB4jmAcyt1 [plasma membrane] (Xenopus tropicalis)
phospho-p-Y1056,Y1188,Y1242-ERBB4 JM-A CYT-1 isoform [plasma membrane] (Xenopus tropicalis)
MAPK family signaling cascades (Xenopus tropicalis)
MAPK1/MAPK3 signaling (Xenopus tropicalis)
RAF/MAP kinase cascade (Xenopus tropicalis)
RAS GEFs promote RAS nucleotide exchange (Xenopus tropicalis)
RAS GEFs [plasma membrane] (Xenopus tropicalis)
GRB2:SOS1:p-Y349,350-SHC1:p-ERBB4 [plasma membrane] (Xenopus tropicalis)
p-Y349,350-SHC1:p-ERBB4 [plasma membrane] (Xenopus tropicalis)
p-ERBB4 homodimers [plasma membrane] (Xenopus tropicalis)
p-ERBB4cyt1 homodimers [plasma membrane] (Xenopus tropicalis)
p-ERBB4jmAcyt1 [plasma membrane] (Xenopus tropicalis)
NRGs/EGF-like ligands:P-ERBB4jmAcyt1 [plasma membrane] (Xenopus tropicalis)
phospho-p-Y1056,Y1188,Y1242-ERBB4 JM-A CYT-1 isoform [plasma membrane] (Xenopus tropicalis)
Signaling by Receptor Tyrosine Kinases (Xenopus tropicalis)
Signaling by ERBB4 (Xenopus tropicalis)
PI3K events in ERBB4 signaling (Xenopus tropicalis)
Binding of p85 subunit of PI3K (PIK3R1) to p-ERBB4cyt1 homodimers (Xenopus tropicalis)
PI3K:p-ERBB4cyt1 [plasma membrane] (Xenopus tropicalis)
p-ERBB4cyt1 homodimers [plasma membrane] (Xenopus tropicalis)
p-ERBB4jmAcyt1 [plasma membrane] (Xenopus tropicalis)
NRGs/EGF-like ligands:P-ERBB4jmAcyt1 [plasma membrane] (Xenopus tropicalis)
phospho-p-Y1056,Y1188,Y1242-ERBB4 JM-A CYT-1 isoform [plasma membrane] (Xenopus tropicalis)
p-ERBB4cyt1 homodimers [plasma membrane] (Xenopus tropicalis)
p-ERBB4jmAcyt1 [plasma membrane] (Xenopus tropicalis)
NRGs/EGF-like ligands:P-ERBB4jmAcyt1 [plasma membrane] (Xenopus tropicalis)
phospho-p-Y1056,Y1188,Y1242-ERBB4 JM-A CYT-1 isoform [plasma membrane] (Xenopus tropicalis)
Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers (Xenopus tropicalis)
PI3K:p-ERBB4cyt1 [plasma membrane] (Xenopus tropicalis)
p-ERBB4cyt1 homodimers [plasma membrane] (Xenopus tropicalis)
p-ERBB4jmAcyt1 [plasma membrane] (Xenopus tropicalis)
NRGs/EGF-like ligands:P-ERBB4jmAcyt1 [plasma membrane] (Xenopus tropicalis)
phospho-p-Y1056,Y1188,Y1242-ERBB4 JM-A CYT-1 isoform [plasma membrane] (Xenopus tropicalis)
SHC1 events in ERBB4 signaling (Xenopus tropicalis)
Phosphorylation of SHC1 by ERBB4 homodimers (Xenopus tropicalis)
SHC1:p-ERBB4 [plasma membrane] (Xenopus tropicalis)
p-ERBB4 homodimers [plasma membrane] (Xenopus tropicalis)
p-ERBB4cyt1 homodimers [plasma membrane] (Xenopus tropicalis)
p-ERBB4jmAcyt1 [plasma membrane] (Xenopus tropicalis)
NRGs/EGF-like ligands:P-ERBB4jmAcyt1 [plasma membrane] (Xenopus tropicalis)
phospho-p-Y1056,Y1188,Y1242-ERBB4 JM-A CYT-1 isoform [plasma membrane] (Xenopus tropicalis)
p-Y349,350-SHC1:p-ERBB4 [plasma membrane] (Xenopus tropicalis)
p-ERBB4 homodimers [plasma membrane] (Xenopus tropicalis)
p-ERBB4cyt1 homodimers [plasma membrane] (Xenopus tropicalis)
p-ERBB4jmAcyt1 [plasma membrane] (Xenopus tropicalis)
NRGs/EGF-like ligands:P-ERBB4jmAcyt1 [plasma membrane] (Xenopus tropicalis)
phospho-p-Y1056,Y1188,Y1242-ERBB4 JM-A CYT-1 isoform [plasma membrane] (Xenopus tropicalis)
RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 (Xenopus tropicalis)
GRB2:SOS1:p-Y349,350-SHC1:p-ERBB4 [plasma membrane] (Xenopus tropicalis)
p-Y349,350-SHC1:p-ERBB4 [plasma membrane] (Xenopus tropicalis)
p-ERBB4 homodimers [plasma membrane] (Xenopus tropicalis)
p-ERBB4cyt1 homodimers [plasma membrane] (Xenopus tropicalis)
p-ERBB4jmAcyt1 [plasma membrane] (Xenopus tropicalis)
NRGs/EGF-like ligands:P-ERBB4jmAcyt1 [plasma membrane] (Xenopus tropicalis)
phospho-p-Y1056,Y1188,Y1242-ERBB4 JM-A CYT-1 isoform [plasma membrane] (Xenopus tropicalis)
Recruitment of GRB2:SOS1 to phosphorylated SHC1 in complex with phosphorylated ERBB4 homodimers (Xenopus tropicalis)
GRB2:SOS1:p-Y349,350-SHC1:p-ERBB4 [plasma membrane] (Xenopus tropicalis)
p-Y349,350-SHC1:p-ERBB4 [plasma membrane] (Xenopus tropicalis)
p-ERBB4 homodimers [plasma membrane] (Xenopus tropicalis)
p-ERBB4cyt1 homodimers [plasma membrane] (Xenopus tropicalis)
p-ERBB4jmAcyt1 [plasma membrane] (Xenopus tropicalis)
NRGs/EGF-like ligands:P-ERBB4jmAcyt1 [plasma membrane] (Xenopus tropicalis)
phospho-p-Y1056,Y1188,Y1242-ERBB4 JM-A CYT-1 isoform [plasma membrane] (Xenopus tropicalis)
p-Y349,350-SHC1:p-ERBB4 [plasma membrane] (Xenopus tropicalis)
p-ERBB4 homodimers [plasma membrane] (Xenopus tropicalis)
p-ERBB4cyt1 homodimers [plasma membrane] (Xenopus tropicalis)
p-ERBB4jmAcyt1 [plasma membrane] (Xenopus tropicalis)
NRGs/EGF-like ligands:P-ERBB4jmAcyt1 [plasma membrane] (Xenopus tropicalis)
phospho-p-Y1056,Y1188,Y1242-ERBB4 JM-A CYT-1 isoform [plasma membrane] (Xenopus tropicalis)
Trans-autophosphorylation of ERBB4 homodimers (Xenopus tropicalis)
p-ERBB4 homodimers [plasma membrane] (Xenopus tropicalis)
p-ERBB4cyt1 homodimers [plasma membrane] (Xenopus tropicalis)
p-ERBB4jmAcyt1 [plasma membrane] (Xenopus tropicalis)
NRGs/EGF-like ligands:P-ERBB4jmAcyt1 [plasma membrane] (Xenopus tropicalis)
phospho-p-Y1056,Y1188,Y1242-ERBB4 JM-A CYT-1 isoform [plasma membrane] (Xenopus tropicalis)
External Reference Information
External Reference
UniProt:A0A6I8R0X7
Reference Genes
ENSEMBL:ENSXETG00000000413
KEGG Gene (Xenopus tropicalis):100493234
Reference Transcript
RefSeq:XM_031892892.1
Other Identifiers
100493234
GO:0000166
GO:0003824
GO:0004672
GO:0004713
GO:0004714
GO:0005524
GO:0005886
GO:0007169
GO:0016020
GO:0016301
GO:0016310
GO:0016740
GO:0023052
GO:0036211
GO:0038127
GO:0042127
GO:0060089
GO:0098590
GO:0140096
Participates
as a component of
NRGs/EGF-like ligands:P-ERBB4jmAcyt1 [plasma membrane] (Xenopus tropicalis)
Other forms of this molecule
phospho-ERBB4jmAcyt1s80 [mitochondrial matrix]
phospho-ERBB4jmAcyt2s80 [mitochondrial matrix]
phospho-ERBB4jmAcyt2s80 [nucleoplasm]
phospho-ERBB4jmAcyt1s80 [nucleoplasm]
phospho-ERBB4jmAcyt2s80 [cytosol]
phospho-ERBB4jmAcyt2m80 [plasma membrane]
phospho-ERBB4jmAcyt1m80 [plasma membrane]
phospho-ERBB4jmAcyt1s80 [cytosol]
phospho-p-Y1172,Y1226-ERBB4 JM-A CYT-2 isoform [plasma membrane]
ERBB4 JM-A CYT-1 isoform [plasma membrane]
ERBB4 JM-B CYT-1 isoform [plasma membrane]
ERBB4 JM-A CYT-2 isoform [plasma membrane]
phospho-p-Y1046,Y1178,Y1232-ERBB4 JM-B CYT-1 isoform [plasma membrane]
Inferred From
p-Y1056,Y1188,Y1242-ERBB4 JM-A CYT-1 isoform [plasma membrane]
(Homo sapiens)
Modified Residues
Name
O4'-phospho-L-tyrosine at 1056 (in Homo sapiens)
Coordinate
1056
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1188 (in Homo sapiens)
Coordinate
1188
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1242 (in Homo sapiens)
Coordinate
1242
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Cross References
RefSeq
XP_031748752.1
Ensembl
ENSXETG00000000413
,
ENSXETP00000078163
,
ENSXETT00000077674
Xenbase
XB-GENE-877077
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