Reactome | COMMD3 [cytosol]

COMMD3 [cytosol]

Stable Identifier

R-SSC-8955113

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

cytosol

Synonyms

COMMD3, A0A4X1TSS3

Locations in the PathwayBrowser

Expand all

Metabolism of proteins (Sus scrofa)

- Post-translational protein modification (Sus scrofa)
  - Neddylation (Sus scrofa)
    - 26S proteasome degrades HIFalpha (Sus scrofa)
      - RBX1:NEDD8-CUL2:EloB,C:VHL:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Sus scrofa)
        
        COMMDs:CCDC22 [cytosol] (Sus scrofa)
        
        COMMDs [cytosol] (Sus scrofa)
        
        COMMD3 [cytosol] (Sus scrofa)
      - ub-hydroxyPro-HIF-alpha:VHL:EloB:EloC:NEDD8-CUL2:RBX1:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Sus scrofa)
        
        RBX1:NEDD8-CUL2:EloB,C:VHL:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Sus scrofa)
        
        COMMDs:CCDC22 [cytosol] (Sus scrofa)
        
        COMMDs [cytosol] (Sus scrofa)
        
        COMMD3 [cytosol] (Sus scrofa)
    - AcM-UBE2M transfers NEDD8 to CRL2 E3 ubiquitin ligase complex (Sus scrofa)
      - NEDD8-AcM-UBE2M:CRL2 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Sus scrofa)
        
        CRL2 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Sus scrofa)
        
        COMMDs:CCDC22 [cytosol] (Sus scrofa)
        
        COMMDs [cytosol] (Sus scrofa)
        
        COMMD3 [cytosol] (Sus scrofa)
      - NEDD8-CRL2 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Sus scrofa)
        
        COMMDs:CCDC22 [cytosol] (Sus scrofa)
        
        COMMDs [cytosol] (Sus scrofa)
        
        COMMD3 [cytosol] (Sus scrofa)
    - COMMDs displace CAND1 from cytosolic CRL E3 ubiquitin ligase complexes (Sus scrofa)
      - COMMDs:CCDC22 [cytosol] (Sus scrofa)
        
        COMMDs [cytosol] (Sus scrofa)
        
        COMMD3 [cytosol] (Sus scrofa)
      - CRL E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Sus scrofa)
        
        CRL1 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Sus scrofa)
        
        COMMDs:CCDC22 [cytosol] (Sus scrofa)
        
        COMMDs [cytosol] (Sus scrofa)
        
        COMMD3 [cytosol] (Sus scrofa)
        
        CRL2 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Sus scrofa)
        
        COMMDs:CCDC22 [cytosol] (Sus scrofa)
        
        COMMDs [cytosol] (Sus scrofa)
        
        COMMD3 [cytosol] (Sus scrofa)
        
        CRL3 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Sus scrofa)
        
        COMMDs:CCDC22 [cytosol] (Sus scrofa)
        
        COMMDs [cytosol] (Sus scrofa)
        
        COMMD3 [cytosol] (Sus scrofa)
        
        CRL5 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Sus scrofa)
        
        COMMDs:CCDC22 [cytosol] (Sus scrofa)
        
        COMMDs [cytosol] (Sus scrofa)
        
        COMMD3 [cytosol] (Sus scrofa)
    - COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes (Sus scrofa)
      - CRL E3 ubiquitin ligase complex:COMMDs:CCDC22:DCUN1Ds [cytosol] (Sus scrofa)
        
        CRL2 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Sus scrofa)
        
        COMMDs:CCDC22 [cytosol] (Sus scrofa)
        
        COMMDs [cytosol] (Sus scrofa)
        
        COMMD3 [cytosol] (Sus scrofa)
        
        CRL5 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Sus scrofa)
        
        COMMDs:CCDC22 [cytosol] (Sus scrofa)
        
        COMMDs [cytosol] (Sus scrofa)
        
        COMMD3 [cytosol] (Sus scrofa)
      - NEDD8 CRL E3 ubiquitin ligases:COMMDs:CCDC22:DCUN1Ds [cytosol] (Sus scrofa)
        
        NEDD8-CRL2 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Sus scrofa)
        
        COMMDs:CCDC22 [cytosol] (Sus scrofa)
        
        COMMDs [cytosol] (Sus scrofa)
        
        COMMD3 [cytosol] (Sus scrofa)
        
        NEDD8-CRL5 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Sus scrofa)
        
        COMMDs:CCDC22 [cytosol] (Sus scrofa)
        
        COMMDs [cytosol] (Sus scrofa)
        
        COMMD3 [cytosol] (Sus scrofa)
    - MyrG-DCUN1D3 binds CRL1 E3 ubiquitin ligase complex (Sus scrofa)
      - CRL1 E3 ubiquitin ligase complex:MyrG-DCUN1D3 [plasma membrane] (Sus scrofa)
        
        CRL1 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Sus scrofa)
        
        COMMDs:CCDC22 [cytosol] (Sus scrofa)
        
        COMMDs [cytosol] (Sus scrofa)
        
        COMMD3 [cytosol] (Sus scrofa)
      - CRL1 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Sus scrofa)
        
        COMMDs:CCDC22 [cytosol] (Sus scrofa)
        
        COMMDs [cytosol] (Sus scrofa)
        
        COMMD3 [cytosol] (Sus scrofa)
    - VHL:EloB,C:NEDD8-CUL2:RBX1 complex binds UBXN7 (Sus scrofa)
      - RBX1:NEDD8-CUL2:EloB,C:VHL:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Sus scrofa)
        
        COMMDs:CCDC22 [cytosol] (Sus scrofa)
        
        COMMDs [cytosol] (Sus scrofa)
        
        COMMD3 [cytosol] (Sus scrofa)
      - RBX1:NEDD8-CUL2:EloB,C:VHL:COMMDs:CCDC22:DCUN1D1,2,4,5:UBXN7 [cytosol] (Sus scrofa)
        
        RBX1:NEDD8-CUL2:EloB,C:VHL:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Sus scrofa)
        
        COMMDs:CCDC22 [cytosol] (Sus scrofa)
        
        COMMDs [cytosol] (Sus scrofa)
        
        COMMD3 [cytosol] (Sus scrofa)
    - VHL:EloB,C:NEDD8-CUL2:RBX1 complex binds hydroxyprolyl-HIF-alpha (Sus scrofa)
      - RBX1:NEDD8-CUL2:EloB,C:VHL:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Sus scrofa)
        
        COMMDs:CCDC22 [cytosol] (Sus scrofa)
        
        COMMDs [cytosol] (Sus scrofa)
        
        COMMD3 [cytosol] (Sus scrofa)
      - RBX1:NEDD8-CUL2:EloB,C:VHL:COMMDs:CCDC22:DCUN1D1,2,4,5:hydroxyPro-HIF-alpha [cytosol] (Sus scrofa)
        
        RBX1:NEDD8-CUL2:EloB,C:VHL:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Sus scrofa)
        
        COMMDs:CCDC22 [cytosol] (Sus scrofa)
        
        COMMDs [cytosol] (Sus scrofa)
        
        COMMD3 [cytosol] (Sus scrofa)
    - VHL:EloB,C:NEDD8-CUL2:RBX1 complex ubiquitinylates HIF-alpha (Sus scrofa)
      - RBX1:NEDD8-CUL2:EloB,C:VHL:COMMDs:CCDC22:DCUN1D1,2,4,5:UBXN7 [cytosol] (Sus scrofa)
        
        RBX1:NEDD8-CUL2:EloB,C:VHL:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Sus scrofa)
        
        COMMDs:CCDC22 [cytosol] (Sus scrofa)
        
        COMMDs [cytosol] (Sus scrofa)
        
        COMMD3 [cytosol] (Sus scrofa)
      - RBX1:NEDD8-CUL2:EloB,C:VHL:COMMDs:CCDC22:DCUN1D1,2,4,5:hydroxyPro-HIF-alpha [cytosol] (Sus scrofa)
        
        RBX1:NEDD8-CUL2:EloB,C:VHL:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Sus scrofa)
        
        COMMDs:CCDC22 [cytosol] (Sus scrofa)
        
        COMMDs [cytosol] (Sus scrofa)
        
        COMMD3 [cytosol] (Sus scrofa)
      - ub-hydroxyPro-HIF-alpha:VHL:EloB:EloC:NEDD8-CUL2:RBX1:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Sus scrofa)
        
        RBX1:NEDD8-CUL2:EloB,C:VHL:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Sus scrofa)
        
        COMMDs:CCDC22 [cytosol] (Sus scrofa)
        
        COMMDs [cytosol] (Sus scrofa)
        
        COMMD3 [cytosol] (Sus scrofa)

External Reference Information

External Reference

UniProt:A0A4X1TSS3

Gene Names

COMMD3

Reference Genes

BioGPS Gene:102167371 COMMD3

ENSEMBL:ENSSSCG00000011082.4

KEGG:ssc:102167371 COMMD3

Monarch:102167371 COMMD3

NCBI Gene:102167371 COMMD3

UCSC:A0A4X1TSS3 COMMD3

Reference Transcript

RefSeq:XM_005668159.3 COMMD3

Other Identifiers

102167371

GO:0006814

Ssc.20943.1.S1_at

Participates

as a candidate of

COMMDs [cytosol] (Sus scrofa)

Other forms of this molecule

COMMD3 [nucleoplasm]

COMMD3 [extracellular region]

COMMD3 [ficolin-1-rich granule lumen]

Inferred From

COMMD3 [cytosol] (Homo sapiens)

Cross References

RefSeq

XP_005668216.1

ENSEMBL

ENSSSCP00000011821, ENSSSCG00000011082, ENSSSCT00000012129

Cite Us!