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EIF2S1:EIF2S2:EIF2S3 [cytosol]
Stable Identifier
R-SSC-72515
Type
Complex
Species
Sus scrofa
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Sus scrofa)
Cellular responses to stress (Sus scrofa)
Cellular response to mitochondrial stress (Sus scrofa)
DELE1(143-515):EIF2AK1 enhances phosphorylation of EIF2S1 (EIF2alpha) (Sus scrofa)
EIF2S1:EIF2S2:EIF2S3 [cytosol] (Sus scrofa)
Unfolded Protein Response (UPR) (Sus scrofa)
PERK regulates gene expression (Sus scrofa)
EIF2AK3 (PERK) phosphorylates EIF2S1 (eIF2-alpha)Phosphorylation of eIF2-alpha by PERK (Sus scrofa)
EIF2S1:EIF2S2:EIF2S3 [cytosol] (Sus scrofa)
Metabolism of proteins (Sus scrofa)
Translation (Sus scrofa)
Eukaryotic Translation Initiation (Sus scrofa)
Cap-dependent Translation Initiation (Sus scrofa)
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S (Sus scrofa)
Translation initiation complex formation (Sus scrofa)
Formation of translation initiation complexes containing mRNA that does not circularize (Sus scrofa)
43S complex [cytosol] (Sus scrofa)
ternary complex [cytosol] (Sus scrofa)
eIF2:GTP [cytosol] (Sus scrofa)
EIF2S1:EIF2S2:EIF2S3 [cytosol] (Sus scrofa)
48S complex [cytosol] (Sus scrofa)
43S complex [cytosol] (Sus scrofa)
ternary complex [cytosol] (Sus scrofa)
eIF2:GTP [cytosol] (Sus scrofa)
EIF2S1:EIF2S2:EIF2S3 [cytosol] (Sus scrofa)
Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation (Sus scrofa)
43S complex [cytosol] (Sus scrofa)
ternary complex [cytosol] (Sus scrofa)
eIF2:GTP [cytosol] (Sus scrofa)
EIF2S1:EIF2S2:EIF2S3 [cytosol] (Sus scrofa)
43S: Ceruloplasmin mRNA:eIF4F:eIF4B:eIF4H:PABP [cytosol] (Sus scrofa)
43S complex [cytosol] (Sus scrofa)
ternary complex [cytosol] (Sus scrofa)
eIF2:GTP [cytosol] (Sus scrofa)
EIF2S1:EIF2S2:EIF2S3 [cytosol] (Sus scrofa)
Formation of the ternary complex, and subsequently, the 43S complex (Sus scrofa)
De novo formation of eIF2:GTP (Sus scrofa)
EIF2S1:EIF2S2:EIF2S3 [cytosol] (Sus scrofa)
eIF2:GTP [cytosol] (Sus scrofa)
EIF2S1:EIF2S2:EIF2S3 [cytosol] (Sus scrofa)
Formation of the 43S pre-initiation complex (Sus scrofa)
43S complex [cytosol] (Sus scrofa)
ternary complex [cytosol] (Sus scrofa)
eIF2:GTP [cytosol] (Sus scrofa)
EIF2S1:EIF2S2:EIF2S3 [cytosol] (Sus scrofa)
ternary complex [cytosol] (Sus scrofa)
eIF2:GTP [cytosol] (Sus scrofa)
EIF2S1:EIF2S2:EIF2S3 [cytosol] (Sus scrofa)
Met-tRNAi binds to eIF2:GTP to form the ternary complex (Sus scrofa)
eIF2:GTP [cytosol] (Sus scrofa)
EIF2S1:EIF2S2:EIF2S3 [cytosol] (Sus scrofa)
ternary complex [cytosol] (Sus scrofa)
eIF2:GTP [cytosol] (Sus scrofa)
EIF2S1:EIF2S2:EIF2S3 [cytosol] (Sus scrofa)
Recycling of eIF2:GDP (Sus scrofa)
Formation of eIF2:GDP:eIF2B intermediate (Sus scrofa)
eIF2:GDP [cytosol] (Sus scrofa)
EIF2S1:EIF2S2:EIF2S3 [cytosol] (Sus scrofa)
eIF2:GDP: eIF2B [cytosol] (Sus scrofa)
EIF2S1:EIF2S2:EIF2S3 [cytosol] (Sus scrofa)
eIF2 activation (Sus scrofa)
eIF2:GDP: eIF2B [cytosol] (Sus scrofa)
EIF2S1:EIF2S2:EIF2S3 [cytosol] (Sus scrofa)
eIF2:GTP [cytosol] (Sus scrofa)
EIF2S1:EIF2S2:EIF2S3 [cytosol] (Sus scrofa)
Ribosomal scanning and start codon recognition (Sus scrofa)
Ribosomal scanning (Sus scrofa)
48S complex [cytosol] (Sus scrofa)
43S complex [cytosol] (Sus scrofa)
ternary complex [cytosol] (Sus scrofa)
eIF2:GTP [cytosol] (Sus scrofa)
EIF2S1:EIF2S2:EIF2S3 [cytosol] (Sus scrofa)
Start codon recognition (Sus scrofa)
48S complex [cytosol] (Sus scrofa)
43S complex [cytosol] (Sus scrofa)
ternary complex [cytosol] (Sus scrofa)
eIF2:GTP [cytosol] (Sus scrofa)
EIF2S1:EIF2S2:EIF2S3 [cytosol] (Sus scrofa)
EIF2S1:EIF2S2:EIF2S3 [cytosol] (Sus scrofa)
L13a-mediated translational silencing of Ceruloplasmin expression (Sus scrofa)
Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA (Sus scrofa)
43S: Ceruloplasmin mRNA:eIF4F:eIF4B:eIF4H:PABP [cytosol] (Sus scrofa)
43S complex [cytosol] (Sus scrofa)
ternary complex [cytosol] (Sus scrofa)
eIF2:GTP [cytosol] (Sus scrofa)
EIF2S1:EIF2S2:EIF2S3 [cytosol] (Sus scrofa)
phospho-L13a associated wth the 3' UTR GAIT element of ceruloplasmin mRNA within the translation initiation complex [cytosol] (Sus scrofa)
43S: Ceruloplasmin mRNA:eIF4F:eIF4B:eIF4H:PABP [cytosol] (Sus scrofa)
43S complex [cytosol] (Sus scrofa)
ternary complex [cytosol] (Sus scrofa)
eIF2:GTP [cytosol] (Sus scrofa)
EIF2S1:EIF2S2:EIF2S3 [cytosol] (Sus scrofa)
Transport of small molecules (Sus scrofa)
ABC-family proteins mediated transport (Sus scrofa)
ABCF1 binds EIF2 (Sus scrofa)
ABCF1:EIF2S1:EIF2S2:EIF2S3 [cytosol] (Sus scrofa)
EIF2S1:EIF2S2:EIF2S3 [cytosol] (Sus scrofa)
EIF2S1:EIF2S2:EIF2S3 [cytosol] (Sus scrofa)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
EIF2S1 [cytosol]
(Sus scrofa)
EIF2S2 [cytosol]
(Sus scrofa)
EIF2S3B [cytosol]
(Sus scrofa)
Participates
as an input of
ABCF1 binds EIF2 (Sus scrofa)
EIF2AK3 (PERK) phosphorylates EIF2S1 (eIF2-alpha)Phosphorylation of eIF2-alpha by PERK (Sus scrofa)
DELE1(143-515):EIF2AK1 enhances phosphorylation of EIF2S1 (EIF2alpha) (Sus scrofa)
De novo formation of eIF2:GTP (Sus scrofa)
Start codon recognition (Sus scrofa)
as a component of
ABCF1:EIF2S1:EIF2S2:EIF2S3 [cytosol] (Sus scrofa)
eIF2:GDP: eIF2B [cytosol] (Sus scrofa)
eIF2:GDP [cytosol] (Sus scrofa)
eIF2:GTP [cytosol] (Sus scrofa)
as an output of
Start codon recognition (Sus scrofa)
Inferred From
EIF2S1:EIF2S2:EIF2S3 [cytosol]
(Homo sapiens)
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