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60S ribosomal complex [cytosol]
Stable Identifier
R-SSC-72499
Type
Complex
Species
Sus scrofa
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Metabolism of RNA (Sus scrofa)
Nonsense-Mediated Decay (NMD) (Sus scrofa)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Sus scrofa)
SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Sus scrofa)
SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Sus scrofa)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Sus scrofa)
80S ribosome [cytosol] (Sus scrofa)
60S ribosomal complex [cytosol] (Sus scrofa)
SMG1:UPF1:EJC:Translated mRNP [cytosol] (Sus scrofa)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Sus scrofa)
80S ribosome [cytosol] (Sus scrofa)
60S ribosomal complex [cytosol] (Sus scrofa)
SMG6 hydrolyzes mRNA with premature termination codon (Sus scrofa)
Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Sus scrofa)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Sus scrofa)
80S ribosome [cytosol] (Sus scrofa)
60S ribosomal complex [cytosol] (Sus scrofa)
UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex (Sus scrofa)
SMG1:UPF1:EJC:Translated mRNP [cytosol] (Sus scrofa)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Sus scrofa)
80S ribosome [cytosol] (Sus scrofa)
60S ribosomal complex [cytosol] (Sus scrofa)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Sus scrofa)
80S ribosome [cytosol] (Sus scrofa)
60S ribosomal complex [cytosol] (Sus scrofa)
p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A (Sus scrofa)
Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Sus scrofa)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Sus scrofa)
80S ribosome [cytosol] (Sus scrofa)
60S ribosomal complex [cytosol] (Sus scrofa)
SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Sus scrofa)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Sus scrofa)
80S ribosome [cytosol] (Sus scrofa)
60S ribosomal complex [cytosol] (Sus scrofa)
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) (Sus scrofa)
Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex (Sus scrofa)
Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Sus scrofa)
80S ribosome [cytosol] (Sus scrofa)
60S ribosomal complex [cytosol] (Sus scrofa)
UPF1:eRF3 Complex on Translated mRNA [cytosol] (Sus scrofa)
Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Sus scrofa)
80S ribosome [cytosol] (Sus scrofa)
60S ribosomal complex [cytosol] (Sus scrofa)
rRNA processing (Sus scrofa)
rRNA processing in the nucleus and cytosol (Sus scrofa)
Major pathway of rRNA processing in the nucleolus and cytosol (Sus scrofa)
12S pre-rRNA is nucleolytically processed to yield 5.8S rRNA (Sus scrofa)
60S ribosomal complex [cytosol] (Sus scrofa)
Metabolism of proteins (Sus scrofa)
Translation (Sus scrofa)
Eukaryotic Translation Initiation (Sus scrofa)
Cap-dependent Translation Initiation (Sus scrofa)
Formation of a pool of free 40S subunits (Sus scrofa)
Release of 40S and 60S subunits from the 80S ribosome (Sus scrofa)
60S ribosomal complex [cytosol] (Sus scrofa)
80S ribosome [cytosol] (Sus scrofa)
60S ribosomal complex [cytosol] (Sus scrofa)
GTP hydrolysis and joining of the 60S ribosomal subunit (Sus scrofa)
The 60S subunit joins the translation initiation complex (Sus scrofa)
60S ribosomal complex [cytosol] (Sus scrofa)
80S:Met-tRNAi:mRNA:eIF5B:GTP [cytosol] (Sus scrofa)
80S ribosome [cytosol] (Sus scrofa)
60S ribosomal complex [cytosol] (Sus scrofa)
eIF5B:GTP is hydrolyzed and released (Sus scrofa)
80S:Met-tRNAi:mRNA [cytosol] (Sus scrofa)
80S ribosome [cytosol] (Sus scrofa)
60S ribosomal complex [cytosol] (Sus scrofa)
80S:Met-tRNAi:mRNA:eIF5B:GTP [cytosol] (Sus scrofa)
80S ribosome [cytosol] (Sus scrofa)
60S ribosomal complex [cytosol] (Sus scrofa)
L13a-mediated translational silencing of Ceruloplasmin expression (Sus scrofa)
Dissociation of L13a from the 60s ribosomal subunit (Sus scrofa)
60S ribosomal complex [cytosol] (Sus scrofa)
Ribosome-associated quality control (Sus scrofa)
PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA (Sus scrofa)
ABCE1:ATP binds PELO:HBS1L-1:GTP:80S ribosome:non-stop mRNA:peptidyl-tRNA with nascent peptide and HBS1L-1:GDP is released (Sus scrofa)
ABCE1:ATP:PELO:80S Ribosome:non-stop mRNA:peptidyl-tRNA with elongating peptide [cytosol] (Sus scrofa)
80S Ribosome:non-stop mRNA:peptidyl-tRNA with elongating peptide [cytosol] (Sus scrofa)
80S ribosome [cytosol] (Sus scrofa)
60S ribosomal complex [cytosol] (Sus scrofa)
PELO:HBS1L-1:GTP:80S ribosome:non-stop mRNA:peptidyl-tRNA with nascent peptide [cytosol] (Sus scrofa)
80S Ribosome:non-stop mRNA:peptidyl-tRNA with elongating peptide [cytosol] (Sus scrofa)
80S ribosome [cytosol] (Sus scrofa)
60S ribosomal complex [cytosol] (Sus scrofa)
ABCE1:PELO:80S Ribosome:non-stop mRNA:peptidyl-tRNA with elongating peptide dissociates yielding ABCE1:40S ribosomal subunit, PELO, and 60S ribosomal subunit:peptidyl-tRNA with nascent peptide (Sus scrofa)
60S ribosomal subunit:peptidyl-tRNA with nascent peptide [cytosol] (Sus scrofa)
60S ribosomal complex [cytosol] (Sus scrofa)
ABCE1:ATP:PELO:80S Ribosome:non-stop mRNA:peptidyl-tRNA with elongating peptide [cytosol] (Sus scrofa)
80S Ribosome:non-stop mRNA:peptidyl-tRNA with elongating peptide [cytosol] (Sus scrofa)
80S ribosome [cytosol] (Sus scrofa)
60S ribosomal complex [cytosol] (Sus scrofa)
PELO:HBS1L-1:GTP binds 80S ribosome:non-stop mRNA:peptidyl-tRNA with nascent peptide (Sus scrofa)
80S Ribosome:non-stop mRNA:peptidyl-tRNA with elongating peptide [cytosol] (Sus scrofa)
80S ribosome [cytosol] (Sus scrofa)
60S ribosomal complex [cytosol] (Sus scrofa)
PELO:HBS1L-1:GTP:80S ribosome:non-stop mRNA:peptidyl-tRNA with nascent peptide [cytosol] (Sus scrofa)
80S Ribosome:non-stop mRNA:peptidyl-tRNA with elongating peptide [cytosol] (Sus scrofa)
80S ribosome [cytosol] (Sus scrofa)
60S ribosomal complex [cytosol] (Sus scrofa)
Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide (Sus scrofa)
LTN1 K48 polyubiquitinates the nascent peptide in NEMF:60S ribosomal subunit:peptidyl-tRNA with nascent peptide (Sus scrofa)
LTN1:TCF25:NEMF:60S ribosomal subunit:peptidyl-tRNA with K48polyUb-nascent peptide-Ala [cytosol] (Sus scrofa)
60S ribosomal complex [cytosol] (Sus scrofa)
LTN1:TCF25:NEMF:60S ribosomal subunit:peptidyl-tRNA with nascent peptide-Ala [cytosol] (Sus scrofa)
60S ribosomal complex [cytosol] (Sus scrofa)
LTN1 and TCF25 bind NEMF:60S ribosomal subunit:peptidyl-tRNA with nascent peptide-Ala (Sus scrofa)
LTN1:TCF25:NEMF:60S ribosomal subunit:peptidyl-tRNA with nascent peptide-Ala [cytosol] (Sus scrofa)
60S ribosomal complex [cytosol] (Sus scrofa)
NEMF:60S ribosomal subunit:peptidyl-tRNA with nascent peptide-Ala [cytosol] (Sus scrofa)
60S ribosomal complex [cytosol] (Sus scrofa)
NEDD8-K699-CUL2:ELOB:ELOC:RBX1:KLHDC10 binds alanine-tailed nascent peptide (Sus scrofa)
NEMF:60S ribosomal subunit:peptidyl-tRNA with nascent peptide-Ala [cytosol] (Sus scrofa)
60S ribosomal complex [cytosol] (Sus scrofa)
NEMF binds 60S ribosomal subunit:peptidyl-tRNA with nascent peptide (Sus scrofa)
60S ribosomal subunit:peptidyl-tRNA with nascent peptide [cytosol] (Sus scrofa)
60S ribosomal complex [cytosol] (Sus scrofa)
NEMF:60S ribosomal subunit:peptidyl-tRNA with nascent peptide [cytosol] (Sus scrofa)
60S ribosomal complex [cytosol] (Sus scrofa)
RCHY1 binds alanine-tailed nascent peptide and Ub:UBE2D2 (Sus scrofa)
NEMF:60S ribosomal subunit:peptidyl-tRNA with nascent peptide-Ala [cytosol] (Sus scrofa)
60S ribosomal complex [cytosol] (Sus scrofa)
ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA (Sus scrofa)
RQT complex binds K63polyUb-80S ribosome:no-go mRNA:peptidyl-tRNA with nascent peptide (Sus scrofa)
K63polyUb-80S Ribosome:no-go mRNA:peptidyl-tRNA with elongating peptide [cytosol] (Sus scrofa)
K63polyUb-80S ribosome [cytosol] (Sus scrofa)
60S ribosomal complex [cytosol] (Sus scrofa)
RQT complex:K63polyUb-80S Ribosome:no-go mRNA:peptidyl tRNA with nascent peptide [cytosol] (Sus scrofa)
K63polyUb-80S Ribosome:no-go mRNA:peptidyl-tRNA with elongating peptide [cytosol] (Sus scrofa)
K63polyUb-80S ribosome [cytosol] (Sus scrofa)
60S ribosomal complex [cytosol] (Sus scrofa)
ZNF598 K63 polyubiquitinates RPS10 (eS10) and RPS20 (uS10) of the 40S ribosomal subunit (Sus scrofa)
K63polyUb-80S Ribosome:no-go mRNA:peptidyl-tRNA with elongating peptide [cytosol] (Sus scrofa)
K63polyUb-80S ribosome [cytosol] (Sus scrofa)
60S ribosomal complex [cytosol] (Sus scrofa)
ZNF598:Ub:UBE2D1,2,3:80S Ribosome:mRNA:peptidyl-tRNA with nascent peptide [cytosol] (Sus scrofa)
80S Ribosome:no-go mRNA:peptidyl-tRNA with elongating peptide [cytosol] (Sus scrofa)
80S ribosome [cytosol] (Sus scrofa)
60S ribosomal complex [cytosol] (Sus scrofa)
ZNF598 and Ub:UBE2D1,2,3 bind stalled 80S ribosome (Sus scrofa)
80S Ribosome:no-go mRNA:peptidyl-tRNA with elongating peptide [cytosol] (Sus scrofa)
80S ribosome [cytosol] (Sus scrofa)
60S ribosomal complex [cytosol] (Sus scrofa)
ZNF598:Ub:UBE2D1,2,3:80S Ribosome:mRNA:peptidyl-tRNA with nascent peptide [cytosol] (Sus scrofa)
80S Ribosome:no-go mRNA:peptidyl-tRNA with elongating peptide [cytosol] (Sus scrofa)
80S ribosome [cytosol] (Sus scrofa)
60S ribosomal complex [cytosol] (Sus scrofa)
SRP-dependent cotranslational protein targeting to membrane (Sus scrofa)
Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP) (Sus scrofa)
SRP:polypeptide+signal:ribosome [cytosol] (Sus scrofa)
ribosome:mRNA:polypeptide+signal [cytosol] (Sus scrofa)
80S ribosome [cytosol] (Sus scrofa)
60S ribosomal complex [cytosol] (Sus scrofa)
ribosome:mRNA:polypeptide+signal [cytosol] (Sus scrofa)
80S ribosome [cytosol] (Sus scrofa)
60S ribosomal complex [cytosol] (Sus scrofa)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
Ghost homologue of 28S rRNA [cytosol]
(Sus scrofa)
Ghost homologue of 5.8S rRNA [cytosol]
(Sus scrofa)
Ghost homologue of 5S rRNA [cytosol]
(Sus scrofa)
Ghost homologue of RPL37A [cytosol]
(Sus scrofa)
Ghost homologue of RPL41 [cytosol]
(Sus scrofa)
Ghost homologue of RPL6 [cytosol]
(Sus scrofa)
Ghost homologue of RPLP0 [cytosol]
(Sus scrofa)
Homologues of RPL13A [cytosol]
(Sus scrofa)
RPL10,RPL10L [cytosol]
(Sus scrofa)
RPL10A [cytosol]
(Sus scrofa)
RPL11 [cytosol]
(Sus scrofa)
RPL12 [cytosol]
(Sus scrofa)
RPL13 [cytosol]
(Sus scrofa)
RPL14 [cytosol]
(Sus scrofa)
RPL15 [cytosol]
(Sus scrofa)
RPL17 [cytosol]
(Sus scrofa)
RPL18 [cytosol]
(Sus scrofa)
RPL18A [cytosol]
(Sus scrofa)
RPL19 [cytosol]
(Sus scrofa)
RPL21 [cytosol]
(Sus scrofa)
RPL22,RPL22L1 [cytosol]
(Sus scrofa)
RPL23 [cytosol]
(Sus scrofa)
RPL23A [cytosol]
(Sus scrofa)
RPL24 [cytosol]
(Sus scrofa)
RPL26,RPL26L1 [cytosol]
(Sus scrofa)
RPL27 [cytosol]
(Sus scrofa)
RPL27A [cytosol]
(Sus scrofa)
RPL28 [cytosol]
(Sus scrofa)
RPL29 [cytosol]
(Sus scrofa)
RPL3,RPL3L [cytosol]
(Sus scrofa)
RPL30 [cytosol]
(Sus scrofa)
RPL31 [cytosol]
(Sus scrofa)
RPL32 [cytosol]
(Sus scrofa)
RPL34 [cytosol]
(Sus scrofa)
RPL35 [cytosol]
(Sus scrofa)
RPL35A [cytosol]
(Sus scrofa)
RPL36 [cytosol]
(Sus scrofa)
RPL36A,RPL36AL [cytosol]
(Sus scrofa)
RPL37 [cytosol]
(Sus scrofa)
RPL38 [cytosol]
(Sus scrofa)
RPL39,RPL39L [cytosol]
(Sus scrofa)
RPL4 [cytosol]
(Sus scrofa)
RPL5 [cytosol]
(Sus scrofa)
RPL7 [cytosol]
(Sus scrofa)
RPL7A [cytosol]
(Sus scrofa)
RPL8 [cytosol]
(Sus scrofa)
RPL9 [cytosol]
(Sus scrofa)
RPLP1 [cytosol]
(Sus scrofa)
RPLP2 [cytosol]
(Sus scrofa)
UBA52 [cytosol]
(Sus scrofa)
Participates
as a component of
VCP hexamer:UFD1:NPLOC4:LTN1:NEMF:TCF25:60S ribosome subunit:peptidyl-tRNA with K48polyUb-nascent peptide-Ala [cytosol] (Sus scrofa)
LTN1:TCF25:NEMF:60S ribosomal subunit:peptidyl-tRNA with K48polyUb-nascent peptide-Ala [cytosol] (Sus scrofa)
60S ribosomal subunit:peptidyl-tRNA with nascent peptide [cytosol] (Sus scrofa)
K63polyUb-80S ribosome [cytosol] (Sus scrofa)
LTN1:TCF25:NEMF:60S ribosomal subunit:peptidyl-tRNA with nascent peptide-Ala [cytosol] (Sus scrofa)
NEMF:60S ribosomal subunit:peptidyl-tRNA with nascent peptide [cytosol] (Sus scrofa)
NEMF:60S ribosomal subunit:peptidyl-tRNA with nascent peptide-Ala [cytosol] (Sus scrofa)
80S ribosome [cytosol] (Sus scrofa)
as an input of
Dissociation of L13a from the 60s ribosomal subunit (Sus scrofa)
The 60S subunit joins the translation initiation complex (Sus scrofa)
as an output of
12S pre-rRNA is nucleolytically processed to yield 5.8S rRNA (Sus scrofa)
Release of 40S and 60S subunits from the 80S ribosome (Sus scrofa)
Inferred From
60S ribosomal complex [cytosol]
(Homo sapiens)
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