Reactome | SF3B1 [nucleoplasm]

SF3B1 [nucleoplasm]

Stable Identifier

R-SSC-71968

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

nucleoplasm

Synonyms

SF3B1, A0A287AV35

Locations in the PathwayBrowser

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Metabolism of RNA (Sus scrofa)

- Processing of Capped Intron-Containing Pre-mRNA (Sus scrofa)
  - mRNA 3'-end processing (Sus scrofa)
    - mRNA Polyadenylation (Sus scrofa)
      - Core CPA complex binds capped pre-mRNA (Sus scrofa)
        
        Core CPA complex:Spliceosomal A complex (uncleaved pre-mRNA) [nucleoplasm] (Sus scrofa)
        
        Spliceosomal A complex (capped, methylated pre-mRNA) [nucleoplasm] (Sus scrofa)
        
        U2 snRNP [nucleoplasm] (Sus scrofa)
        
        SF3B [nucleoplasm] (Sus scrofa)
        
        SF3B1 [nucleoplasm] (Sus scrofa)
        
        Spliceosomal A complex (capped, methylated pre-mRNA) [nucleoplasm] (Sus scrofa)
        
        U2 snRNP [nucleoplasm] (Sus scrofa)
        
        SF3B [nucleoplasm] (Sus scrofa)
        
        SF3B1 [nucleoplasm] (Sus scrofa)
      - PABPN1-stimulated PAPOL synthesizes polyA tail at distal 3'UTR PAS (Sus scrofa)
        
        Ub-K63-CPA:PABPN1:Spliceosomal A complex (pre-mRNA polyadenylated at distal 3'UTR PAS) [nucleoplasm] (Sus scrofa)
        
        Spliceosomal A complex (pre-mRNA polyadenylated at distal 3'UTR PAS) [nucleoplasm] (Sus scrofa)
        
        U2 snRNP [nucleoplasm] (Sus scrofa)
        
        SF3B [nucleoplasm] (Sus scrofa)
        
        SF3B1 [nucleoplasm] (Sus scrofa)
        
        Ub-K63-CPA:Spliceosomal A complex (pre-mRNA cleaved at distal 3'UTR PAS) [nucleoplasm] (Sus scrofa)
        
        Spliceosomal A complex (pre-mRNA cleaved at distal 3'UTR PAS) [nucleoplasm] (Sus scrofa)
        
        U2 snRNP [nucleoplasm] (Sus scrofa)
        
        SF3B [nucleoplasm] (Sus scrofa)
        
        SF3B1 [nucleoplasm] (Sus scrofa)
      - PABPN1-stimulated PAPOL synthesizes polyA tail at intronic PAS (Sus scrofa)
        
        Ub-K63-CPA:PABPN1:Spliceosomal A complex (pre-mRNA polyadenylated at intronic PAS) [nucleoplasm] (Sus scrofa)
        
        Spliceosomal A complex (pre-mRNA polyadenylated at intronic PAS) [nucleoplasm] (Sus scrofa)
        
        U2 snRNP [nucleoplasm] (Sus scrofa)
        
        SF3B [nucleoplasm] (Sus scrofa)
        
        SF3B1 [nucleoplasm] (Sus scrofa)
        
        Ub-K63-CPA:Spliceosomal A complex (pre-mRNA cleaved at intronic PAS) [nucleoplasm] (Sus scrofa)
        
        Spliceosomal A complex (pre-mRNA cleaved at intronal PAS) [nucleoplasm] (Sus scrofa)
        
        U2 snRNP [nucleoplasm] (Sus scrofa)
        
        SF3B [nucleoplasm] (Sus scrofa)
        
        SF3B1 [nucleoplasm] (Sus scrofa)
      - PABPN1-stimulated PAPOL synthesizes polyA tail at proximal 3'UTR PAS (Sus scrofa)
        
        Ub-K63-CPA:PABPN1:Spliceosomal A complex (pre-mRNA polyadenylated at proximal 3'UTR PAS) [nucleoplasm] (Sus scrofa)
        
        Spliceosomal A complex (pre-mRNA polyadenylated at proximal 3'UTR PAS) [nucleoplasm] (Sus scrofa)
        
        U2 snRNP [nucleoplasm] (Sus scrofa)
        
        SF3B [nucleoplasm] (Sus scrofa)
        
        SF3B1 [nucleoplasm] (Sus scrofa)
        
        Ub-K63-CPA:Spliceosomal A complex (pre-mRNA cleaved at proximal 3'UTR PAS) [nucleoplasm] (Sus scrofa)
        
        Spliceosomal A complex (pre-mRNA cleaved at proximal 3'UTR PAS) [nucleoplasm] (Sus scrofa)
        
        U2 snRNP [nucleoplasm] (Sus scrofa)
        
        SF3B [nucleoplasm] (Sus scrofa)
        
        SF3B1 [nucleoplasm] (Sus scrofa)
      - PP1 dephosphorylates RNA Pol II (Sus scrofa)
        
        CPA:Spliceosomal A complex (uncleaved pre-mRNA) [nucleoplasm] (Sus scrofa)
        
        Spliceosomal A complex (capped, methylated pre-mRNA) [nucleoplasm] (Sus scrofa)
        
        U2 snRNP [nucleoplasm] (Sus scrofa)
        
        SF3B [nucleoplasm] (Sus scrofa)
        
        SF3B1 [nucleoplasm] (Sus scrofa)
        
        CPA:Spliceosomal A complex (uncleaved pre-mRNA, RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Sus scrofa)
        
        Spliceosomal A complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Sus scrofa)
        
        U2 snRNP [nucleoplasm] (Sus scrofa)
        
        SF3B [nucleoplasm] (Sus scrofa)
        
        SF3B1 [nucleoplasm] (Sus scrofa)
      - RBBP6 activates CPSF complex (Sus scrofa)
        
        CPA:Spliceosomal A complex (uncleaved pre-mRNA, RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Sus scrofa)
        
        Spliceosomal A complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Sus scrofa)
        
        U2 snRNP [nucleoplasm] (Sus scrofa)
        
        SF3B [nucleoplasm] (Sus scrofa)
        
        SF3B1 [nucleoplasm] (Sus scrofa)
        
        Ub-K63-CPA:Spliceosomal A complex (uncleaved pre-mRNA, RNA Pol II Ser2 dephosphorylated) [nucleoplasm] (Sus scrofa)
        
        Spliceosomal A complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Sus scrofa)
        
        U2 snRNP [nucleoplasm] (Sus scrofa)
        
        SF3B [nucleoplasm] (Sus scrofa)
        
        SF3B1 [nucleoplasm] (Sus scrofa)
  - mRNA Splicing (Sus scrofa)
    - mRNA Splicing - Minor Pathway (Sus scrofa)
      - ATAC spliceosome mediated 3' splice site cleavage, exon ligation (Sus scrofa)
        
        ATAC C Complex [nucleoplasm] (Sus scrofa)
        
        U12 snRNP [nucleoplasm] (Sus scrofa)
        
        SF3B [nucleoplasm] (Sus scrofa)
        
        SF3B1 [nucleoplasm] (Sus scrofa)
        
        U12 snRNP [nucleoplasm] (Sus scrofa)
        
        SF3B [nucleoplasm] (Sus scrofa)
        
        SF3B1 [nucleoplasm] (Sus scrofa)
      - ATAC spliceosome mediated Lariat formation,5' splice site cleavage (Sus scrofa)
        
        ATAC C Complex [nucleoplasm] (Sus scrofa)
        
        U12 snRNP [nucleoplasm] (Sus scrofa)
        
        SF3B [nucleoplasm] (Sus scrofa)
        
        SF3B1 [nucleoplasm] (Sus scrofa)
      - Formation of AT-AC B Complex (Sus scrofa)
        
        ATAC A Complex [nucleoplasm] (Sus scrofa)
        
        U12 snRNP [nucleoplasm] (Sus scrofa)
        
        SF3B [nucleoplasm] (Sus scrofa)
        
        SF3B1 [nucleoplasm] (Sus scrofa)
        
        ATAC B Complex [nucleoplasm] (Sus scrofa)
        
        ATAC A Complex [nucleoplasm] (Sus scrofa)
        
        U12 snRNP [nucleoplasm] (Sus scrofa)
        
        SF3B [nucleoplasm] (Sus scrofa)
        
        SF3B1 [nucleoplasm] (Sus scrofa)
      - Formation of AT-AC C complex (Sus scrofa)
        
        ATAC B Complex [nucleoplasm] (Sus scrofa)
        
        ATAC A Complex [nucleoplasm] (Sus scrofa)
        
        U12 snRNP [nucleoplasm] (Sus scrofa)
        
        SF3B [nucleoplasm] (Sus scrofa)
        
        SF3B1 [nucleoplasm] (Sus scrofa)
        
        ATAC C Complex [nucleoplasm] (Sus scrofa)
        
        U12 snRNP [nucleoplasm] (Sus scrofa)
        
        SF3B [nucleoplasm] (Sus scrofa)
        
        SF3B1 [nucleoplasm] (Sus scrofa)

External Reference Information

External Reference

UniProt:A0A287AV35

Gene Names

SF3B1

Reference Genes

BioGPS Gene:100157887 SF3B1

ENSEMBL:ENSSSCG00000016075.5

Monarch:100157887 SF3B1

NCBI Gene:100157887 SF3B1

UCSC:A0A287AV35 SF3B1

Reference Transcript

Other Identifiers

100157887

GO:0000245

GO:0000398

GO:0000785

GO:0003729

GO:0005634

GO:0005681

GO:0005686

GO:0005689

GO:0006397

GO:0008380

GO:0016071

GO:0016607

GO:0031981

GO:0065003

GO:0071004

GO:0071013

Ssc.12295.1.A1_at

Ssc.3000.1.S1_at

Participates

as a component of

Inferred From

SF3B1 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

XP_020931173.1, XP_020931174.1

ENSEMBL

ENSSSCP00000047792, ENSSSCG00000016075, ENSSSCT00000055542

VGNC

95492

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