Reactome | MCM7 [nucleoplasm]

MCM7 [nucleoplasm]

Stable Identifier

R-SSC-68555

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

nucleoplasm

Synonyms

MCM7, A0A286ZJM4

Locations in the PathwayBrowser

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Cell Cycle (Sus scrofa)

- Cell Cycle Checkpoints (Sus scrofa)
  - G2/M Checkpoints (Sus scrofa)
    - Activation of ATR in response to replication stress (Sus scrofa)
      - Activation of claspin (Sus scrofa)
        
        Cdc45:CDK:DDK:Mcm10:Activated claspin:pre-replicative complex [nucleoplasm] (Sus scrofa)
        
        CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Sus scrofa)
        
        CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Sus scrofa)
        
        MCM10:active pre-replicative complex [nucleoplasm] (Sus scrofa)
        
        active pre-replicative complex [nucleoplasm] (Sus scrofa)
        
        MCM2-7 [nucleoplasm] (Sus scrofa)
        
        MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Sus scrofa)
        
        MCM4:MCM6:MCM7 [nucleoplasm] (Sus scrofa)
        
        MCM7 [nucleoplasm] (Sus scrofa)
        
        Cdc45:CDK:DDK:Mcm10:claspin:pre-replicative complex [nucleoplasm] (Sus scrofa)
        
        CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Sus scrofa)
        
        CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Sus scrofa)
        
        MCM10:active pre-replicative complex [nucleoplasm] (Sus scrofa)
        
        active pre-replicative complex [nucleoplasm] (Sus scrofa)
        
        MCM2-7 [nucleoplasm] (Sus scrofa)
        
        MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Sus scrofa)
        
        MCM4:MCM6:MCM7 [nucleoplasm] (Sus scrofa)
        
        MCM7 [nucleoplasm] (Sus scrofa)
      - Loading of claspin onto DNA during replication origin firing (Sus scrofa)
        
        CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Sus scrofa)
        
        CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Sus scrofa)
        
        MCM10:active pre-replicative complex [nucleoplasm] (Sus scrofa)
        
        active pre-replicative complex [nucleoplasm] (Sus scrofa)
        
        MCM2-7 [nucleoplasm] (Sus scrofa)
        
        MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Sus scrofa)
        
        MCM4:MCM6:MCM7 [nucleoplasm] (Sus scrofa)
        
        MCM7 [nucleoplasm] (Sus scrofa)
        
        Cdc45:CDK:DDK:Mcm10:claspin:pre-replicative complex [nucleoplasm] (Sus scrofa)
        
        CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Sus scrofa)
        
        CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Sus scrofa)
        
        MCM10:active pre-replicative complex [nucleoplasm] (Sus scrofa)
        
        active pre-replicative complex [nucleoplasm] (Sus scrofa)
        
        MCM2-7 [nucleoplasm] (Sus scrofa)
        
        MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Sus scrofa)
        
        MCM4:MCM6:MCM7 [nucleoplasm] (Sus scrofa)
        
        MCM7 [nucleoplasm] (Sus scrofa)
- Cell Cycle, Mitotic (Sus scrofa)
  - Mitotic G1 phase and G1/S transition (Sus scrofa)
    - G1/S Transition (Sus scrofa)
      - Activation of the pre-replicative complex (Sus scrofa)
        
        CDK and DDK associate with the Mcm10:pre-replicative complex (Sus scrofa)
        
        CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Sus scrofa)
        
        MCM10:active pre-replicative complex [nucleoplasm] (Sus scrofa)
        
        active pre-replicative complex [nucleoplasm] (Sus scrofa)
        
        MCM2-7 [nucleoplasm] (Sus scrofa)
        
        MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Sus scrofa)
        
        MCM4:MCM6:MCM7 [nucleoplasm] (Sus scrofa)
        
        MCM7 [nucleoplasm] (Sus scrofa)
        
        MCM10:active pre-replicative complex [nucleoplasm] (Sus scrofa)
        
        active pre-replicative complex [nucleoplasm] (Sus scrofa)
        
        MCM2-7 [nucleoplasm] (Sus scrofa)
        
        MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Sus scrofa)
        
        MCM4:MCM6:MCM7 [nucleoplasm] (Sus scrofa)
        
        MCM7 [nucleoplasm] (Sus scrofa)
        
        Cdc45 associates with the pre-replicative complex at the origin (Sus scrofa)
        
        CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Sus scrofa)
        
        MCM10:active pre-replicative complex [nucleoplasm] (Sus scrofa)
        
        active pre-replicative complex [nucleoplasm] (Sus scrofa)
        
        MCM2-7 [nucleoplasm] (Sus scrofa)
        
        MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Sus scrofa)
        
        MCM4:MCM6:MCM7 [nucleoplasm] (Sus scrofa)
        
        MCM7 [nucleoplasm] (Sus scrofa)
        
        CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Sus scrofa)
        
        CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Sus scrofa)
        
        MCM10:active pre-replicative complex [nucleoplasm] (Sus scrofa)
        
        active pre-replicative complex [nucleoplasm] (Sus scrofa)
        
        MCM2-7 [nucleoplasm] (Sus scrofa)
        
        MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Sus scrofa)
        
        MCM4:MCM6:MCM7 [nucleoplasm] (Sus scrofa)
        
        MCM7 [nucleoplasm] (Sus scrofa)
        
        Cdt1 is displaced from the pre-replicative complex (Sus scrofa)
        
        MCM10:active pre-replicative complex [nucleoplasm] (Sus scrofa)
        
        active pre-replicative complex [nucleoplasm] (Sus scrofa)
        
        MCM2-7 [nucleoplasm] (Sus scrofa)
        
        MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Sus scrofa)
        
        MCM4:MCM6:MCM7 [nucleoplasm] (Sus scrofa)
        
        MCM7 [nucleoplasm] (Sus scrofa)
        
        MCM10:pre-replicative complex [nucleoplasm] (Sus scrofa)
        
        pre-replicative complex [nucleoplasm] (Sus scrofa)
        
        MCM2-7 [nucleoplasm] (Sus scrofa)
        
        MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Sus scrofa)
        
        MCM4:MCM6:MCM7 [nucleoplasm] (Sus scrofa)
        
        MCM7 [nucleoplasm] (Sus scrofa)
        
        DNA Replication Factor A (RPA) associates with the pre-replicative complex at the origin (Sus scrofa)
        
        CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Sus scrofa)
        
        CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Sus scrofa)
        
        MCM10:active pre-replicative complex [nucleoplasm] (Sus scrofa)
        
        active pre-replicative complex [nucleoplasm] (Sus scrofa)
        
        MCM2-7 [nucleoplasm] (Sus scrofa)
        
        MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Sus scrofa)
        
        MCM4:MCM6:MCM7 [nucleoplasm] (Sus scrofa)
        
        MCM7 [nucleoplasm] (Sus scrofa)
        
        CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Sus scrofa)
        
        CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Sus scrofa)
        
        CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Sus scrofa)
        
        MCM10:active pre-replicative complex [nucleoplasm] (Sus scrofa)
        
        active pre-replicative complex [nucleoplasm] (Sus scrofa)
        
        MCM2-7 [nucleoplasm] (Sus scrofa)
        
        MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Sus scrofa)
        
        MCM4:MCM6:MCM7 [nucleoplasm] (Sus scrofa)
        
        MCM7 [nucleoplasm] (Sus scrofa)
        
        DNA polymerase alpha:primase binds at the origin (Sus scrofa)
        
        CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Sus scrofa)
        
        CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Sus scrofa)
        
        CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Sus scrofa)
        
        MCM10:active pre-replicative complex [nucleoplasm] (Sus scrofa)
        
        active pre-replicative complex [nucleoplasm] (Sus scrofa)
        
        MCM2-7 [nucleoplasm] (Sus scrofa)
        
        MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Sus scrofa)
        
        MCM4:MCM6:MCM7 [nucleoplasm] (Sus scrofa)
        
        MCM7 [nucleoplasm] (Sus scrofa)
        
        DNA polymerase epsilon binds at the origin (Sus scrofa)
        
        CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Sus scrofa)
        
        CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Sus scrofa)
        
        CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Sus scrofa)
        
        MCM10:active pre-replicative complex [nucleoplasm] (Sus scrofa)
        
        active pre-replicative complex [nucleoplasm] (Sus scrofa)
        
        MCM2-7 [nucleoplasm] (Sus scrofa)
        
        MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Sus scrofa)
        
        MCM4:MCM6:MCM7 [nucleoplasm] (Sus scrofa)
        
        MCM7 [nucleoplasm] (Sus scrofa)
        
        Mcm10 associates with the pre-replicative complex, stabilizing Mcm2-7 (Sus scrofa)
        
        MCM10:pre-replicative complex [nucleoplasm] (Sus scrofa)
        
        pre-replicative complex [nucleoplasm] (Sus scrofa)
        
        MCM2-7 [nucleoplasm] (Sus scrofa)
        
        MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Sus scrofa)
        
        MCM4:MCM6:MCM7 [nucleoplasm] (Sus scrofa)
        
        MCM7 [nucleoplasm] (Sus scrofa)
        
        pre-replicative complex [nucleoplasm] (Sus scrofa)
        
        MCM2-7 [nucleoplasm] (Sus scrofa)
        
        MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Sus scrofa)
        
        MCM4:MCM6:MCM7 [nucleoplasm] (Sus scrofa)
        
        MCM7 [nucleoplasm] (Sus scrofa)
        
        Mcm2-7 is phosphorylated by DDK (Sus scrofa)
        
        MCM2-7 [nucleoplasm] (Sus scrofa)
        
        MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Sus scrofa)
        
        MCM4:MCM6:MCM7 [nucleoplasm] (Sus scrofa)
        
        MCM7 [nucleoplasm] (Sus scrofa)
        
        p-MCM2-7 [nucleoplasm] (Sus scrofa)
        
        MCM2-7 [nucleoplasm] (Sus scrofa)
        
        MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Sus scrofa)
        
        MCM4:MCM6:MCM7 [nucleoplasm] (Sus scrofa)
        
        MCM7 [nucleoplasm] (Sus scrofa)
  - S Phase (Sus scrofa)
    - Synthesis of DNA (Sus scrofa)
      - Switching of origins to a post-replicative state (Sus scrofa)
        
        Mcm4,6,7 trimer forms and associates with the replication fork (Sus scrofa)
        
        MCM2-7 [nucleoplasm] (Sus scrofa)
        
        MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Sus scrofa)
        
        MCM4:MCM6:MCM7 [nucleoplasm] (Sus scrofa)
        
        MCM7 [nucleoplasm] (Sus scrofa)
        
        MCM4:MCM6:MCM7 [nucleoplasm] (Sus scrofa)
        
        MCM7 [nucleoplasm] (Sus scrofa)
        
        Orc1 removal from chromatin (Sus scrofa)
        
        Orc1 is phosphorylated by cyclin A/CDK2 (Sus scrofa)
        
        pre-replicative complex (Orc1-minus) [nucleoplasm] (Sus scrofa)
        
        MCM2-7 [nucleoplasm] (Sus scrofa)
        
        MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Sus scrofa)
        
        MCM4:MCM6:MCM7 [nucleoplasm] (Sus scrofa)
        
        MCM7 [nucleoplasm] (Sus scrofa)
        
        pre-replicative complex [nucleoplasm] (Sus scrofa)
        
        MCM2-7 [nucleoplasm] (Sus scrofa)
        
        MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Sus scrofa)
        
        MCM4:MCM6:MCM7 [nucleoplasm] (Sus scrofa)
        
        MCM7 [nucleoplasm] (Sus scrofa)

DNA Replication (Sus scrofa)

- DNA Replication Pre-Initiation (Sus scrofa)
  - Activation of the pre-replicative complex (Sus scrofa)
    - CDK and DDK associate with the Mcm10:pre-replicative complex (Sus scrofa)
      - CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Sus scrofa)
        
        MCM10:active pre-replicative complex [nucleoplasm] (Sus scrofa)
        
        active pre-replicative complex [nucleoplasm] (Sus scrofa)
        
        MCM2-7 [nucleoplasm] (Sus scrofa)
        
        MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Sus scrofa)
        
        MCM4:MCM6:MCM7 [nucleoplasm] (Sus scrofa)
        
        MCM7 [nucleoplasm] (Sus scrofa)
      - MCM10:active pre-replicative complex [nucleoplasm] (Sus scrofa)
        
        active pre-replicative complex [nucleoplasm] (Sus scrofa)
        
        MCM2-7 [nucleoplasm] (Sus scrofa)
        
        MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Sus scrofa)
        
        MCM4:MCM6:MCM7 [nucleoplasm] (Sus scrofa)
        
        MCM7 [nucleoplasm] (Sus scrofa)
    - Cdc45 associates with the pre-replicative complex at the origin (Sus scrofa)
      - CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Sus scrofa)
        
        MCM10:active pre-replicative complex [nucleoplasm] (Sus scrofa)
        
        active pre-replicative complex [nucleoplasm] (Sus scrofa)
        
        MCM2-7 [nucleoplasm] (Sus scrofa)
        
        MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Sus scrofa)
        
        MCM4:MCM6:MCM7 [nucleoplasm] (Sus scrofa)
        
        MCM7 [nucleoplasm] (Sus scrofa)
      - CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Sus scrofa)
        
        CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Sus scrofa)
        
        MCM10:active pre-replicative complex [nucleoplasm] (Sus scrofa)
        
        active pre-replicative complex [nucleoplasm] (Sus scrofa)
        
        MCM2-7 [nucleoplasm] (Sus scrofa)
        
        MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Sus scrofa)
        
        MCM4:MCM6:MCM7 [nucleoplasm] (Sus scrofa)
        
        MCM7 [nucleoplasm] (Sus scrofa)
    - Cdt1 is displaced from the pre-replicative complex (Sus scrofa)
      - MCM10:active pre-replicative complex [nucleoplasm] (Sus scrofa)
        
        active pre-replicative complex [nucleoplasm] (Sus scrofa)
        
        MCM2-7 [nucleoplasm] (Sus scrofa)
        
        MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Sus scrofa)
        
        MCM4:MCM6:MCM7 [nucleoplasm] (Sus scrofa)
        
        MCM7 [nucleoplasm] (Sus scrofa)
      - MCM10:pre-replicative complex [nucleoplasm] (Sus scrofa)
        
        pre-replicative complex [nucleoplasm] (Sus scrofa)
        
        MCM2-7 [nucleoplasm] (Sus scrofa)
        
        MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Sus scrofa)
        
        MCM4:MCM6:MCM7 [nucleoplasm] (Sus scrofa)
        
        MCM7 [nucleoplasm] (Sus scrofa)
    - DNA Replication Factor A (RPA) associates with the pre-replicative complex at the origin (Sus scrofa)
      - CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Sus scrofa)
        
        CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Sus scrofa)
        
        MCM10:active pre-replicative complex [nucleoplasm] (Sus scrofa)
        
        active pre-replicative complex [nucleoplasm] (Sus scrofa)
        
        MCM2-7 [nucleoplasm] (Sus scrofa)
        
        MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Sus scrofa)
        
        MCM4:MCM6:MCM7 [nucleoplasm] (Sus scrofa)
        
        MCM7 [nucleoplasm] (Sus scrofa)
      - CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Sus scrofa)
        
        CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Sus scrofa)
        
        CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Sus scrofa)
        
        MCM10:active pre-replicative complex [nucleoplasm] (Sus scrofa)
        
        active pre-replicative complex [nucleoplasm] (Sus scrofa)
        
        MCM2-7 [nucleoplasm] (Sus scrofa)
        
        MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Sus scrofa)
        
        MCM4:MCM6:MCM7 [nucleoplasm] (Sus scrofa)
        
        MCM7 [nucleoplasm] (Sus scrofa)
    - DNA polymerase alpha:primase binds at the origin (Sus scrofa)
      - CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Sus scrofa)
        
        CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Sus scrofa)
        
        CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Sus scrofa)
        
        MCM10:active pre-replicative complex [nucleoplasm] (Sus scrofa)
        
        active pre-replicative complex [nucleoplasm] (Sus scrofa)
        
        MCM2-7 [nucleoplasm] (Sus scrofa)
        
        MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Sus scrofa)
        
        MCM4:MCM6:MCM7 [nucleoplasm] (Sus scrofa)
        
        MCM7 [nucleoplasm] (Sus scrofa)
    - DNA polymerase epsilon binds at the origin (Sus scrofa)
      - CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Sus scrofa)
        
        CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Sus scrofa)
        
        CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Sus scrofa)
        
        MCM10:active pre-replicative complex [nucleoplasm] (Sus scrofa)
        
        active pre-replicative complex [nucleoplasm] (Sus scrofa)
        
        MCM2-7 [nucleoplasm] (Sus scrofa)
        
        MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Sus scrofa)
        
        MCM4:MCM6:MCM7 [nucleoplasm] (Sus scrofa)
        
        MCM7 [nucleoplasm] (Sus scrofa)
    - Mcm10 associates with the pre-replicative complex, stabilizing Mcm2-7 (Sus scrofa)
      - MCM10:pre-replicative complex [nucleoplasm] (Sus scrofa)
        
        pre-replicative complex [nucleoplasm] (Sus scrofa)
        
        MCM2-7 [nucleoplasm] (Sus scrofa)
        
        MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Sus scrofa)
        
        MCM4:MCM6:MCM7 [nucleoplasm] (Sus scrofa)
        
        MCM7 [nucleoplasm] (Sus scrofa)
      - pre-replicative complex [nucleoplasm] (Sus scrofa)
        
        MCM2-7 [nucleoplasm] (Sus scrofa)
        
        MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Sus scrofa)
        
        MCM4:MCM6:MCM7 [nucleoplasm] (Sus scrofa)
        
        MCM7 [nucleoplasm] (Sus scrofa)
    - Mcm2-7 is phosphorylated by DDK (Sus scrofa)
      - MCM2-7 [nucleoplasm] (Sus scrofa)
        
        MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Sus scrofa)
        
        MCM4:MCM6:MCM7 [nucleoplasm] (Sus scrofa)
        
        MCM7 [nucleoplasm] (Sus scrofa)
      - p-MCM2-7 [nucleoplasm] (Sus scrofa)
        
        MCM2-7 [nucleoplasm] (Sus scrofa)
        
        MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Sus scrofa)
        
        MCM4:MCM6:MCM7 [nucleoplasm] (Sus scrofa)
        
        MCM7 [nucleoplasm] (Sus scrofa)
  - Assembly of the pre-replicative complex (Sus scrofa)
    - Formation of MCM2-7 complex (Sus scrofa)
      - MCM2-7 [nucleoplasm] (Sus scrofa)
        
        MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Sus scrofa)
        
        MCM4:MCM6:MCM7 [nucleoplasm] (Sus scrofa)
        
        MCM7 [nucleoplasm] (Sus scrofa)
      - MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Sus scrofa)
        
        MCM4:MCM6:MCM7 [nucleoplasm] (Sus scrofa)
        
        MCM7 [nucleoplasm] (Sus scrofa)
    - MCM2 binds MCM4:MCM6:MCM7 heterotrimer (Sus scrofa)
      - MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Sus scrofa)
        
        MCM4:MCM6:MCM7 [nucleoplasm] (Sus scrofa)
        
        MCM7 [nucleoplasm] (Sus scrofa)
      - MCM4:MCM6:MCM7 [nucleoplasm] (Sus scrofa)
        
        MCM7 [nucleoplasm] (Sus scrofa)
    - MCM4, MCM6 and MCM7 form a heterotrimer (Sus scrofa)
      - MCM4:MCM6:MCM7 [nucleoplasm] (Sus scrofa)
        
        MCM7 [nucleoplasm] (Sus scrofa)
      - MCM7 [nucleoplasm] (Sus scrofa)
- Synthesis of DNA (Sus scrofa)
  - Switching of origins to a post-replicative state (Sus scrofa)
    - Mcm4,6,7 trimer forms and associates with the replication fork (Sus scrofa)
      - MCM2-7 [nucleoplasm] (Sus scrofa)
        
        MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Sus scrofa)
        
        MCM4:MCM6:MCM7 [nucleoplasm] (Sus scrofa)
        
        MCM7 [nucleoplasm] (Sus scrofa)
      - MCM4:MCM6:MCM7 [nucleoplasm] (Sus scrofa)
        
        MCM7 [nucleoplasm] (Sus scrofa)
    - Orc1 removal from chromatin (Sus scrofa)
      - Orc1 is phosphorylated by cyclin A/CDK2 (Sus scrofa)
        
        pre-replicative complex (Orc1-minus) [nucleoplasm] (Sus scrofa)
        
        MCM2-7 [nucleoplasm] (Sus scrofa)
        
        MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Sus scrofa)
        
        MCM4:MCM6:MCM7 [nucleoplasm] (Sus scrofa)
        
        MCM7 [nucleoplasm] (Sus scrofa)
        
        pre-replicative complex [nucleoplasm] (Sus scrofa)
        
        MCM2-7 [nucleoplasm] (Sus scrofa)
        
        MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Sus scrofa)
        
        MCM4:MCM6:MCM7 [nucleoplasm] (Sus scrofa)
        
        MCM7 [nucleoplasm] (Sus scrofa)

External Reference Information

External Reference

UniProt:A0A286ZJM4

Gene Names

MCM7

Reference Genes

BioGPS Gene:110259871 MCM7

ENSEMBL:ENSSSCG00000032180.2

KEGG:ssc:110259871 MCM7

Monarch:110259871 MCM7

NCBI Gene:110259871 MCM7

UCSC:A0A286ZJM4 MCM7

Reference Transcript

RefSeq:XM_021086193.1 MCM7

Other Identifiers

110259871

GO:0000166

GO:0000727

GO:0003677

GO:0003678

GO:0003697

GO:0003824

GO:0004386

GO:0005524

GO:0005634

GO:0005694

GO:0006260

GO:0006270

GO:0006271

GO:0006281

GO:0006310

GO:0006974

GO:0008283

GO:0016787

GO:0016887

GO:0017116

GO:0032991

GO:0042555

GO:0071162

GO:0071466

GO:0140097

GO:0140657

Ssc.17030.1.S1_at

Participates

as an input of

MCM4, MCM6 and MCM7 form a heterotrimer (Sus scrofa)

as a component of

MCM4:MCM6:MCM7 [nucleoplasm] (Sus scrofa)

Inferred From

MCM7 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

XP_020941852.1

ENSEMBL

ENSSSCG00000032180, ENSSSCT00000041433, ENSSSCP00000050669

VGNC

90076

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