Reactome | phospho-PPP2R5B [cytosol]

phospho-PPP2R5B [cytosol]

Stable Identifier

R-SSC-6811453

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

cytosol

Synonyms

p-S368-PPP2R5B, F1RQR5

Locations in the PathwayBrowser

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Signal Transduction (Sus scrofa)

- Intracellular signaling by second messengers (Sus scrofa)
  - PIP3 activates AKT signaling (Sus scrofa)
    - Negative regulation of the PI3K/AKT network (Sus scrofa)
      - PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Sus scrofa)
        
        MAPKs phosphorylate PP2A (Sus scrofa)
        
        p-S368-PPP2R5B,p-S337-PPP2R5C [cytosol] (Sus scrofa)
        
        phospho-PPP2R5B [cytosol] (Sus scrofa)

External Reference Information

External Reference

UniProt:F1RQR5

Gene Names

PPP2R5B

Reference Genes

BioGPS Gene:100516242 PPP2R5B

ENSEMBL:ENSSSCG00000013016.4

KEGG Gene (Sus scrofa):100516242 PPP2R5B

Monarch:100516242 PPP2R5B

NCBI Gene:100516242 PPP2R5B

Reference Transcript

RefSeq:XM_005660724.2 PPP2R5B

Other Identifiers

100516242

GO:0000159

GO:0005634

GO:0005829

GO:0007165

GO:0019888

GO:0023052

GO:0043226

GO:0072542

GO:0098772

Ssc.4642.1.S1_at

Participates

as a member of

p-S368-PPP2R5B,p-S337-PPP2R5C [cytosol] (Sus scrofa)

Other forms of this molecule

PPP2R5B [cytosol]

Inferred From

p-S368-PPP2R5B [cytosol] (Homo sapiens)

Modified Residues

Name

O-phospho-L-serine at 368 (in Homo sapiens)

Coordinate

368

PsiMod Name

O-phospho-L-serine [MOD:00046]

PsiMod Definition

A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.

Cross References

RefSeq

XP_005660781.1

OpenTargets

ENSG00000068971

Ensembl

ENSSSCT00000014227, ENSSSCG00000013016, ENSSSCP00000013841

VGNC

91752

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