Reactome | ICE1 [nucleoplasm]

ICE1 [nucleoplasm]

Stable Identifier

R-SSC-6807433

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

nucleoplasm

Synonyms

ICE1, A0A287A0W8

Locations in the PathwayBrowser

Expand all

Gene expression (Transcription) (Sus scrofa)

- RNA Polymerase II Transcription (Sus scrofa)
  - RNA polymerase II transcribes snRNA genes (Sus scrofa)
    - CBCAP complex binds 7-methylguanosine cap of snRNA (Sus scrofa)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Sus scrofa)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Sus scrofa)
        
        LEC [nucleoplasm] (Sus scrofa)
        
        ICE1 [nucleoplasm] (Sus scrofa)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Sus scrofa)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Sus scrofa)
        
        LEC [nucleoplasm] (Sus scrofa)
        
        ICE1 [nucleoplasm] (Sus scrofa)
    - Integrator complex processes the 3' end of snRNA (Sus scrofa)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Sus scrofa)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Sus scrofa)
        
        LEC [nucleoplasm] (Sus scrofa)
        
        ICE1 [nucleoplasm] (Sus scrofa)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:Initiation factors:snRNA gene [nucleoplasm] (Sus scrofa)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Sus scrofa)
        
        LEC [nucleoplasm] (Sus scrofa)
        
        ICE1 [nucleoplasm] (Sus scrofa)
    - Pre-snRNA is elongated and capped with 7-methylguanosine (Sus scrofa)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Sus scrofa)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Sus scrofa)
        
        LEC [nucleoplasm] (Sus scrofa)
        
        ICE1 [nucleoplasm] (Sus scrofa)
      - RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Sus scrofa)
        
        RNA polymerase II (phospho-Ser5,7 CTD):RDRP1A,B:RDRP2:RPAP2:Integrator:LEC [nucleoplasm] (Sus scrofa)
        
        LEC [nucleoplasm] (Sus scrofa)
        
        ICE1 [nucleoplasm] (Sus scrofa)
    - Pre-snRNA transcript initiation, Integrator binding, LEC binding (Sus scrofa)
      - LEC [nucleoplasm] (Sus scrofa)
        
        ICE1 [nucleoplasm] (Sus scrofa)
      - RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Sus scrofa)
        
        RNA polymerase II (phospho-Ser5,7 CTD):RDRP1A,B:RDRP2:RPAP2:Integrator:LEC [nucleoplasm] (Sus scrofa)
        
        LEC [nucleoplasm] (Sus scrofa)
        
        ICE1 [nucleoplasm] (Sus scrofa)

External Reference Information

External Reference

UniProt:A0A287A0W8

Gene Names

ICE1

Reference Genes

ENSEMBL:ENSSSCG00000031547.3

Other Identifiers

102164398

GO:0000791

GO:0005634

GO:0005654

GO:0005694

GO:0006351

GO:0006355

GO:0006886

GO:0008023

GO:0015030

GO:0016073

GO:0016604

GO:0030674

GO:0031334

GO:0035363

GO:0042795

GO:0042796

GO:0043226

GO:0045945

GO:0060090

GO:0065003

GO:0090316

Ssc.10656.1.A1_at

Ssc.10656.2.S1_at

Ssc.27930.1.S1_at

Participates

as a component of

LEC [nucleoplasm] (Sus scrofa)

Inferred From

ICE1 [nucleoplasm] (Homo sapiens)

Cross References

OpenTargets

ENSG00000164151

Ensembl

ENSSSCP00000037569, ENSSSCG00000031547, ENSSSCT00000062767