Reactome | ANAPC15 [cytosol]

ANAPC15 [cytosol]

Stable Identifier

R-SSC-6805140

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

cytosol

Synonyms

ANAPC15, F1SUX1

Locations in the PathwayBrowser

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Cell Cycle (Sus scrofa)

- Cell Cycle Checkpoints (Sus scrofa)
  - Mitotic Spindle Checkpoint (Sus scrofa)
    - Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components (Sus scrofa)
      - Inactivation of APC/C via direct inhibition of the APC/C complex (Sus scrofa)
        
        Binding of the MCC complex to the APC/C complex (Sus scrofa)
        
        MCC:APC/C complex [cytosol] (Sus scrofa)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Sus scrofa)
        
        ANAPC15 [cytosol] (Sus scrofa)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Sus scrofa)
        
        ANAPC15 [cytosol] (Sus scrofa)
- Cell Cycle, Mitotic (Sus scrofa)
  - M Phase (Sus scrofa)
    - Mitotic Metaphase and Anaphase (Sus scrofa)
      - Mitotic Anaphase (Sus scrofa)
        
        Separation of Sister Chromatids (Sus scrofa)
        
        Association of Securin with Cdc20:APC/C complex (Sus scrofa)
        
        CDC20:p-APC/C [cytosol] (Sus scrofa)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Sus scrofa)
        
        ANAPC15 [cytosol] (Sus scrofa)
        
        CDC20:p-APC/C:PTTG1 [cytosol] (Sus scrofa)
        
        CDC20:p-APC/C [cytosol] (Sus scrofa)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Sus scrofa)
        
        ANAPC15 [cytosol] (Sus scrofa)
        
        Degradation of multiubiquitinated Securin (Sus scrofa)
        
        CDC20:p-APC/C [cytosol] (Sus scrofa)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Sus scrofa)
        
        ANAPC15 [cytosol] (Sus scrofa)
        
        CDC20:pAPC/C:K11polyUb-PTTG1 [cytosol] (Sus scrofa)
        
        CDC20:p-APC/C [cytosol] (Sus scrofa)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Sus scrofa)
        
        ANAPC15 [cytosol] (Sus scrofa)
        
        Ubiquitination of Securin by phospho-APC/C:Cdc20 complex (Sus scrofa)
        
        CDC20:p-APC/C:PTTG1 [cytosol] (Sus scrofa)
        
        CDC20:p-APC/C [cytosol] (Sus scrofa)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Sus scrofa)
        
        ANAPC15 [cytosol] (Sus scrofa)
        
        CDC20:pAPC/C:K11polyUb-PTTG1 [cytosol] (Sus scrofa)
        
        CDC20:p-APC/C [cytosol] (Sus scrofa)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Sus scrofa)
        
        ANAPC15 [cytosol] (Sus scrofa)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Sus scrofa)
        
        ANAPC15 [cytosol] (Sus scrofa)
  - Regulation of mitotic cell cycle (Sus scrofa)
    - APC/C-mediated degradation of cell cycle proteins (Sus scrofa)
      - APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 (Sus scrofa)
        
        Association of cell cycle proteins with the APC/C:Cdh1 complex (Sus scrofa)
        
        cell cycle proteins:phospho-APC/C:Cdh1 complex [cytosol] (Sus scrofa)
        
        phospho-APC/C:Cdh1 complex [cytosol] (Sus scrofa)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Sus scrofa)
        
        ANAPC15 [cytosol] (Sus scrofa)
        
        phospho-APC/C:Cdh1 complex [cytosol] (Sus scrofa)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Sus scrofa)
        
        ANAPC15 [cytosol] (Sus scrofa)
        
        Degradation of multiubiquitinated cell cycle proteins (Sus scrofa)
        
        multiubiquitinated cell cycle protein:APC/C:Cdh1 complex [cytosol] (Sus scrofa)
        
        cell cycle proteins:phospho-APC/C:Cdh1 complex [cytosol] (Sus scrofa)
        
        phospho-APC/C:Cdh1 complex [cytosol] (Sus scrofa)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Sus scrofa)
        
        ANAPC15 [cytosol] (Sus scrofa)
        
        phospho-APC/C:Cdh1 complex [cytosol] (Sus scrofa)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Sus scrofa)
        
        ANAPC15 [cytosol] (Sus scrofa)
        
        Ubiquitination of cell cycle proteins targeted by the APC/C:Cdh1complex (Sus scrofa)
        
        cell cycle proteins:phospho-APC/C:Cdh1 complex [cytosol] (Sus scrofa)
        
        phospho-APC/C:Cdh1 complex [cytosol] (Sus scrofa)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Sus scrofa)
        
        ANAPC15 [cytosol] (Sus scrofa)
        
        multiubiquitinated cell cycle protein:APC/C:Cdh1 complex [cytosol] (Sus scrofa)
        
        cell cycle proteins:phospho-APC/C:Cdh1 complex [cytosol] (Sus scrofa)
        
        phospho-APC/C:Cdh1 complex [cytosol] (Sus scrofa)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Sus scrofa)
        
        ANAPC15 [cytosol] (Sus scrofa)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Sus scrofa)
        
        ANAPC15 [cytosol] (Sus scrofa)
      - Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins (Sus scrofa)
        
        APC/C:Cdc20 mediated degradation of mitotic proteins (Sus scrofa)
        
        APC/C:Cdc20 mediated degradation of Cyclin B (Sus scrofa)
        
        Association of Cyclin B:Cdc2 with Cdc20:APC/C complex (Sus scrofa)
        
        CDC20:p-APC/C [cytosol] (Sus scrofa)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Sus scrofa)
        
        ANAPC15 [cytosol] (Sus scrofa)
        
        Cdc20:phospho-APC/C:Cyclin B:Cdc2 complex [cytosol] (Sus scrofa)
        
        CDC20:p-APC/C [cytosol] (Sus scrofa)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Sus scrofa)
        
        ANAPC15 [cytosol] (Sus scrofa)
        
        Degradation of multiubiquitinated Cyclin B (Sus scrofa)
        
        CDC20:p-APC/C [cytosol] (Sus scrofa)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Sus scrofa)
        
        ANAPC15 [cytosol] (Sus scrofa)
        
        multiubiquitinated Cyclin B:Cdc2:Cdc20:phospho-APC/C complex [cytosol] (Sus scrofa)
        
        Cdc20:phospho-APC/C:Cyclin B:Cdc2 complex [cytosol] (Sus scrofa)
        
        CDC20:p-APC/C [cytosol] (Sus scrofa)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Sus scrofa)
        
        ANAPC15 [cytosol] (Sus scrofa)
        
        Ubiquitination of Cyclin B by phospho-APC/C:Cdc20 complex (Sus scrofa)
        
        Cdc20:phospho-APC/C:Cyclin B:Cdc2 complex [cytosol] (Sus scrofa)
        
        CDC20:p-APC/C [cytosol] (Sus scrofa)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Sus scrofa)
        
        ANAPC15 [cytosol] (Sus scrofa)
        
        multiubiquitinated Cyclin B:Cdc2:Cdc20:phospho-APC/C complex [cytosol] (Sus scrofa)
        
        Cdc20:phospho-APC/C:Cyclin B:Cdc2 complex [cytosol] (Sus scrofa)
        
        CDC20:p-APC/C [cytosol] (Sus scrofa)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Sus scrofa)
        
        ANAPC15 [cytosol] (Sus scrofa)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Sus scrofa)
        
        ANAPC15 [cytosol] (Sus scrofa)
        
        APC/C:Cdc20 mediated degradation of Securin (Sus scrofa)
        
        Association of Securin with Cdc20:APC/C complex (Sus scrofa)
        
        CDC20:p-APC/C [cytosol] (Sus scrofa)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Sus scrofa)
        
        ANAPC15 [cytosol] (Sus scrofa)
        
        CDC20:p-APC/C:PTTG1 [cytosol] (Sus scrofa)
        
        CDC20:p-APC/C [cytosol] (Sus scrofa)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Sus scrofa)
        
        ANAPC15 [cytosol] (Sus scrofa)
        
        Degradation of multiubiquitinated Securin (Sus scrofa)
        
        CDC20:p-APC/C [cytosol] (Sus scrofa)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Sus scrofa)
        
        ANAPC15 [cytosol] (Sus scrofa)
        
        CDC20:pAPC/C:K11polyUb-PTTG1 [cytosol] (Sus scrofa)
        
        CDC20:p-APC/C [cytosol] (Sus scrofa)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Sus scrofa)
        
        ANAPC15 [cytosol] (Sus scrofa)
        
        Ubiquitination of Securin by phospho-APC/C:Cdc20 complex (Sus scrofa)
        
        CDC20:p-APC/C:PTTG1 [cytosol] (Sus scrofa)
        
        CDC20:p-APC/C [cytosol] (Sus scrofa)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Sus scrofa)
        
        ANAPC15 [cytosol] (Sus scrofa)
        
        CDC20:pAPC/C:K11polyUb-PTTG1 [cytosol] (Sus scrofa)
        
        CDC20:p-APC/C [cytosol] (Sus scrofa)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Sus scrofa)
        
        ANAPC15 [cytosol] (Sus scrofa)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Sus scrofa)
        
        ANAPC15 [cytosol] (Sus scrofa)
        
        APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint (Sus scrofa)
        
        APC-Cdc20 mediated degradation of Nek2A (Sus scrofa)
        
        Degradation of multiubiquitinated Nek2A (Sus scrofa)
        
        MCC:APC/C complex [cytosol] (Sus scrofa)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Sus scrofa)
        
        ANAPC15 [cytosol] (Sus scrofa)
        
        Multiubiquitinated Nek2A [cytosol] (Sus scrofa)
        
        Nek2A:MCC:APC/C complex [cytosol] (Sus scrofa)
        
        MCC:APC/C complex [cytosol] (Sus scrofa)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Sus scrofa)
        
        ANAPC15 [cytosol] (Sus scrofa)
        
        Multiubiquitination of Nek2A (Sus scrofa)
        
        Multiubiquitinated Nek2A [cytosol] (Sus scrofa)
        
        Nek2A:MCC:APC/C complex [cytosol] (Sus scrofa)
        
        MCC:APC/C complex [cytosol] (Sus scrofa)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Sus scrofa)
        
        ANAPC15 [cytosol] (Sus scrofa)
        
        Nek2A:MCC:APC/C complex [cytosol] (Sus scrofa)
        
        MCC:APC/C complex [cytosol] (Sus scrofa)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Sus scrofa)
        
        ANAPC15 [cytosol] (Sus scrofa)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Sus scrofa)
        
        ANAPC15 [cytosol] (Sus scrofa)
        
        Cdc20:Phospho-APC/C mediated degradation of Cyclin A (Sus scrofa)
        
        Association of Cyclin A with the APC/C (Sus scrofa)
        
        Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Sus scrofa)
        
        MCC:APC/C complex [cytosol] (Sus scrofa)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Sus scrofa)
        
        ANAPC15 [cytosol] (Sus scrofa)
        
        MCC:APC/C complex [cytosol] (Sus scrofa)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Sus scrofa)
        
        ANAPC15 [cytosol] (Sus scrofa)
        
        Degradation multiubiquitinated Cyclin A (Sus scrofa)
        
        MCC:APC/C complex [cytosol] (Sus scrofa)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Sus scrofa)
        
        ANAPC15 [cytosol] (Sus scrofa)
        
        multiubiquitinated Cyclin A associated with MCC:APC/C complex [cytosol] (Sus scrofa)
        
        Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Sus scrofa)
        
        MCC:APC/C complex [cytosol] (Sus scrofa)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Sus scrofa)
        
        ANAPC15 [cytosol] (Sus scrofa)
        
        Ubiquitination of Cyclin A by APC/C:Cdc20 complex (Sus scrofa)
        
        Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Sus scrofa)
        
        MCC:APC/C complex [cytosol] (Sus scrofa)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Sus scrofa)
        
        ANAPC15 [cytosol] (Sus scrofa)
        
        MCC:APC/C complex [cytosol] (Sus scrofa)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Sus scrofa)
        
        ANAPC15 [cytosol] (Sus scrofa)
        
        multiubiquitinated Cyclin A associated with MCC:APC/C complex [cytosol] (Sus scrofa)
        
        Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Sus scrofa)
        
        MCC:APC/C complex [cytosol] (Sus scrofa)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Sus scrofa)
        
        ANAPC15 [cytosol] (Sus scrofa)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Sus scrofa)
        
        ANAPC15 [cytosol] (Sus scrofa)
        
        Activation of APC/C:Cdc20 by dissociation of Cdc20:phospho-APC/C from Cdc20:phospho-APC/C:Mad2:Bub3:BubR1 (Sus scrofa)
        
        CDC20:p-APC/C [cytosol] (Sus scrofa)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Sus scrofa)
        
        ANAPC15 [cytosol] (Sus scrofa)
        
        MCC:APC/C complex [cytosol] (Sus scrofa)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Sus scrofa)
        
        ANAPC15 [cytosol] (Sus scrofa)
      - Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase (Sus scrofa)
        
        Association of Cdh1 with the APC/C (Sus scrofa)
        
        phospho-APC/C:Cdh1 complex [cytosol] (Sus scrofa)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Sus scrofa)
        
        ANAPC15 [cytosol] (Sus scrofa)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Sus scrofa)
        
        ANAPC15 [cytosol] (Sus scrofa)
        
        Dissociation of Cdc20 from APC/C complex (Sus scrofa)
        
        CDC20:p-APC/C [cytosol] (Sus scrofa)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Sus scrofa)
        
        ANAPC15 [cytosol] (Sus scrofa)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Sus scrofa)
        
        ANAPC15 [cytosol] (Sus scrofa)
      - Regulation of APC/C activators between G1/S and early anaphase (Sus scrofa)
        
        Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components (Sus scrofa)
        
        Inactivation of APC/C via direct inhibition of the APC/C complex (Sus scrofa)
        
        Binding of the MCC complex to the APC/C complex (Sus scrofa)
        
        MCC:APC/C complex [cytosol] (Sus scrofa)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Sus scrofa)
        
        ANAPC15 [cytosol] (Sus scrofa)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Sus scrofa)
        
        ANAPC15 [cytosol] (Sus scrofa)
  - S Phase (Sus scrofa)
    - Synthesis of DNA (Sus scrofa)
      - Switching of origins to a post-replicative state (Sus scrofa)
        
        CDK-mediated phosphorylation and removal of Cdc6 (Sus scrofa)
        
        Cytoplasmic phosphorylated Cdc6 is ubiquitinated by the anaphase-promoting complex (Sus scrofa)
        
        phospho-APC/C:Cdh1 complex [cytosol] (Sus scrofa)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Sus scrofa)
        
        ANAPC15 [cytosol] (Sus scrofa)

External Reference Information

External Reference

UniProt:F1SUX1

Gene Names

ANAPC15

Reference Genes

BioGPS Gene:100520682 ANAPC15

ENSEMBL:ENSSSCG00000014806.5

Monarch:100520682 ANAPC15

NCBI Gene:100520682 ANAPC15

UCSC:F1SUX1 ANAPC15

Reference Transcript

Other Identifiers

GO:0005680

GO:0030163

GO:0031145

GO:0051301

GO:0070936

GO:0070979

GO:0090266

GO:0141198

Ssc.11211.1.A1_at

Participates

as a component of

phosphorylated anaphase promoting complex (APC/C) [cytosol] (Sus scrofa)

Other forms of this molecule

ANAPC15 [nucleoplasm]

Inferred From

ANAPC15 [cytosol] (Homo sapiens)

Cross References

RefSeq

XP_005653739.1, XP_005653735.1, XP_020918119.1, XP_020918118.1, XP_020918120.1, XP_020918123.1, XP_020918122.1, XP_020918121.1, XP_020918124.1, XP_005653734.1, XP_005653733.1

ENSEMBL

ENSSSCT00000045153, ENSSSCP00000056099, ENSSSCG00000014806

VGNC

85295

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