Reactome | TC-NER incision complex: 5'-incised damaged DNA:trimmed nascent mRNA:(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm]

TC-NER incision complex: 5'-incised damaged DNA:trimmed nascent mRNA:(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm]

Stable Identifier

R-SSC-6782219

Type

Complex

Species

Sus scrofa

Compartment

nucleoplasm

Locations in the PathwayBrowser

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General

This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Participants

components

(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Sus scrofa)
5'-incised damaged DNA:trimmed nascent mRNA [nucleoplasm]
ERCC1:ERCC4 [nucleoplasm] (Sus scrofa)
ERCC5 [nucleoplasm] (Sus scrofa)
ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Sus scrofa)
Ghost homologue of ERCC6 [nucleoplasm] (Sus scrofa)
TCEA1 [nucleoplasm] (Sus scrofa)
TFIIH [nucleoplasm] (Sus scrofa)
Ubiquitinated RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Sus scrofa)
UVSSA:USP7 [nucleoplasm] (Sus scrofa)
XAB2 complex [nucleoplasm] (Sus scrofa)
XPA [nucleoplasm] (Sus scrofa)

Participates

as an input of

3' incision by ERCC5 (XPG) in TC-NER (Sus scrofa)

as an output of

DNA polymerases delta, epsilon or kappa bind the TC-NER site (Sus scrofa)

Inferred From

TC-NER incision complex: 5'-incised damaged DNA:trimmed nascent mRNA:(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)

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