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IL35 [extracellular region]
Stable Identifier
R-SSC-622267
Type
Complex
Species
Sus scrofa
Compartment
extracellular region
Locations in the PathwayBrowser
Expand all
Immune System (Sus scrofa)
Cytokine Signaling in Immune system (Sus scrofa)
Signaling by Interleukins (Sus scrofa)
Interleukin-12 family signaling (Sus scrofa)
Interleukin-35 Signalling (Sus scrofa)
IL35 binds IL-12RB2:IL6ST receptor (Sus scrofa)
IL35 [extracellular region] (Sus scrofa)
IL35:IL6ST:JAK1:IL12RB2:JAK2 [plasma membrane] (Sus scrofa)
IL35 [extracellular region] (Sus scrofa)
IL35 binds IL12RB2:IL12RB2 receptor (Sus scrofa)
IL35 [extracellular region] (Sus scrofa)
IL35:(IL12RB2:JAK2 dimer) [plasma membrane] (Sus scrofa)
IL35 [extracellular region] (Sus scrofa)
IL35 binds IL27RA:IL12RB2 receptor (Sus scrofa)
IL35 [extracellular region] (Sus scrofa)
IL35:IL27RA:JAK1:IL12RB2:JAK2 [plasma membrane] (Sus scrofa)
IL35 [extracellular region] (Sus scrofa)
IL35 binds IL6ST:IL6ST receptor (Sus scrofa)
IL-35:(IL6ST:JAK1:JAK2) dimer [plasma membrane] (Sus scrofa)
IL35 [extracellular region] (Sus scrofa)
IL35 [extracellular region] (Sus scrofa)
Interleukin-35 translocates from the ER lumen to the extracellular region (Sus scrofa)
IL35 [extracellular region] (Sus scrofa)
JAK1,JAK2 bound to IL27RA:IL12RB2 receptor are phosphorylated (Sus scrofa)
IL35:IL27RA:JAK1:IL12RB2:JAK2 [plasma membrane] (Sus scrofa)
IL35 [extracellular region] (Sus scrofa)
IL35:IL27RA:p-JAK1:IL12RB2:p-JAK2 [plasma membrane] (Sus scrofa)
IL35 [extracellular region] (Sus scrofa)
JAK1,JAK2 bound to IL27RA:IL12RB2 receptor phosphorylate STAT1,STAT3 (Sus scrofa)
IL-35:IL27RA:p-JAK1:IL12RB2:p-JAK2:p-STAT1:p-STAT3 [plasma membrane] (Sus scrofa)
IL12A:EBI3:IL12RB2:p-JAK1:IL27RA:p-JAK2 [plasma membrane] (Sus scrofa)
IL35 [extracellular region] (Sus scrofa)
IL35:IL27RA:p-JAK1:IL12RB2:p-JAK2:STAT1:STAT3 [plasma membrane] (Sus scrofa)
IL12A:EBI3:IL12RB2:p-JAK1:IL27RA:p-JAK2 [plasma membrane] (Sus scrofa)
IL35 [extracellular region] (Sus scrofa)
JAK1/JAK2 bound to IL12RB2:IL6ST receptor phosphorylates STAT1 and STAT4 (Sus scrofa)
IL35:IL6ST:p-JAK1:IL12RB2:p-JAK2:STAT1:STAT4 [plasma membrane] (Sus scrofa)
STAT1:IL12A:EBI3:IL6ST:p-JAK1:IL12RB2:p-JAK2 [plasma membrane] (Sus scrofa)
IL35:IL6ST:p-JAK1:IL12RB2:p-JAK2 [plasma membrane] (Sus scrofa)
IL35 [extracellular region] (Sus scrofa)
IL35:IL6ST:p-JAK1:IL12RB2:p-JAK2:p-STAT1:p-STAT4 [plasma membrane] (Sus scrofa)
IL35:IL6ST:p-JAK1:IL12RB2:p-JAK2 [plasma membrane] (Sus scrofa)
IL35 [extracellular region] (Sus scrofa)
JAK1/JAK2 bound to IL35:IL6ST:IL12RB2 receptor are phosphorylated (Sus scrofa)
IL35:IL6ST:JAK1:IL12RB2:JAK2 [plasma membrane] (Sus scrofa)
IL35 [extracellular region] (Sus scrofa)
IL35:IL6ST:p-JAK1:IL12RB2:p-JAK2 [plasma membrane] (Sus scrofa)
IL35 [extracellular region] (Sus scrofa)
JAK1/JAK2/TYK2 bound to IL6ST:IL6ST are phosphorylated (Sus scrofa)
IL-35:(IL6ST:JAK1:JAK2) dimer [plasma membrane] (Sus scrofa)
IL35 [extracellular region] (Sus scrofa)
IL35:(IL6ST:p-JAK1:p-JAK2:p-TYK2) dimer [plasma membrane] (Sus scrofa)
IL35 [extracellular region] (Sus scrofa)
JAK1/JAK2/TYK2 bound to IL6ST:IL6ST phosphorylate STAT1 (Sus scrofa)
IL-35:(IL6ST:p-JAK1:p-JAK2) dimer: STAT1 [plasma membrane] (Sus scrofa)
IL-35:(IL6ST:p-JAK1:p-JAK2) dimer [plasma membrane] (Sus scrofa)
IL35 [extracellular region] (Sus scrofa)
IL-35:(IL6ST:p-JAK1:p-JAK2) dimer:p-STAT1 [plasma membrane] (Sus scrofa)
IL-35:(IL6ST:p-JAK1:p-JAK2) dimer [plasma membrane] (Sus scrofa)
IL35 [extracellular region] (Sus scrofa)
JAK2 bound to IL12RB2:IL12RB2 phosphorylate STAT4 (Sus scrofa)
IL35:(IL12RB2:p-JAK2) dimer:STAT4 [plasma membrane] (Sus scrofa)
IL35:(IL12RB2:p-JAK2) dimer [plasma membrane] (Sus scrofa)
IL35 [extracellular region] (Sus scrofa)
IL35:(IL12RB2:p-JAK2) dimer:p-STAT4 [plasma membrane] (Sus scrofa)
IL35:(IL12RB2:p-JAK2) dimer [plasma membrane] (Sus scrofa)
IL35 [extracellular region] (Sus scrofa)
JAK2 in IL12RB2:IL12RB2 receptor is phosphorylated (Sus scrofa)
IL35:(IL12RB2:JAK2 dimer) [plasma membrane] (Sus scrofa)
IL35 [extracellular region] (Sus scrofa)
IL35:(IL12RB2:p-JAK2) dimer [plasma membrane] (Sus scrofa)
IL35 [extracellular region] (Sus scrofa)
STAT1 and STAT4 associate with IL12RB2:IL6ST receptor (Sus scrofa)
IL35:IL6ST:p-JAK1:IL12RB2:p-JAK2 [plasma membrane] (Sus scrofa)
IL35 [extracellular region] (Sus scrofa)
IL35:IL6ST:p-JAK1:IL12RB2:p-JAK2:STAT1:STAT4 [plasma membrane] (Sus scrofa)
STAT1:IL12A:EBI3:IL6ST:p-JAK1:IL12RB2:p-JAK2 [plasma membrane] (Sus scrofa)
IL35:IL6ST:p-JAK1:IL12RB2:p-JAK2 [plasma membrane] (Sus scrofa)
IL35 [extracellular region] (Sus scrofa)
STAT1 associates with IL6ST:IL6ST (Sus scrofa)
IL-35:(IL6ST:p-JAK1:p-JAK2) dimer [plasma membrane] (Sus scrofa)
IL35 [extracellular region] (Sus scrofa)
IL-35:(IL6ST:p-JAK1:p-JAK2) dimer: STAT1 [plasma membrane] (Sus scrofa)
IL-35:(IL6ST:p-JAK1:p-JAK2) dimer [plasma membrane] (Sus scrofa)
IL35 [extracellular region] (Sus scrofa)
STAT1,STAT3 associate with IL27RA:IL12RB2 receptor (Sus scrofa)
IL35:IL27RA:p-JAK1:IL12RB2:p-JAK2 [plasma membrane] (Sus scrofa)
IL35 [extracellular region] (Sus scrofa)
IL35:IL27RA:p-JAK1:IL12RB2:p-JAK2:STAT1:STAT3 [plasma membrane] (Sus scrofa)
IL12A:EBI3:IL12RB2:p-JAK1:IL27RA:p-JAK2 [plasma membrane] (Sus scrofa)
IL35 [extracellular region] (Sus scrofa)
STAT4 binds IL12RB2:IL12RB2 (Sus scrofa)
IL35:(IL12RB2:p-JAK2) dimer [plasma membrane] (Sus scrofa)
IL35 [extracellular region] (Sus scrofa)
IL35:(IL12RB2:p-JAK2) dimer:STAT4 [plasma membrane] (Sus scrofa)
IL35:(IL12RB2:p-JAK2) dimer [plasma membrane] (Sus scrofa)
IL35 [extracellular region] (Sus scrofa)
p-STAT1 and p-STAT4 dissociate from IL12RB2:IL6ST receptor (Sus scrofa)
IL35:IL6ST:p-JAK1:IL12RB2:p-JAK2 [plasma membrane] (Sus scrofa)
IL35 [extracellular region] (Sus scrofa)
IL35:IL6ST:p-JAK1:IL12RB2:p-JAK2:p-STAT1:p-STAT4 [plasma membrane] (Sus scrofa)
IL35:IL6ST:p-JAK1:IL12RB2:p-JAK2 [plasma membrane] (Sus scrofa)
IL35 [extracellular region] (Sus scrofa)
p-STAT1 dissociates from IL6ST:IL6ST (Sus scrofa)
IL-35:(IL6ST:p-JAK1:p-JAK2) dimer [plasma membrane] (Sus scrofa)
IL35 [extracellular region] (Sus scrofa)
IL-35:(IL6ST:p-JAK1:p-JAK2) dimer:p-STAT1 [plasma membrane] (Sus scrofa)
IL-35:(IL6ST:p-JAK1:p-JAK2) dimer [plasma membrane] (Sus scrofa)
IL35 [extracellular region] (Sus scrofa)
p-STAT1, p-STAT3 dissociate from IL27RA:IL12RB2 receptor (Sus scrofa)
IL-35:IL27RA:p-JAK1:IL12RB2:p-JAK2:p-STAT1:p-STAT3 [plasma membrane] (Sus scrofa)
IL12A:EBI3:IL12RB2:p-JAK1:IL27RA:p-JAK2 [plasma membrane] (Sus scrofa)
IL35 [extracellular region] (Sus scrofa)
IL35:IL27RA:p-JAK1:IL12RB2:p-JAK2 [plasma membrane] (Sus scrofa)
IL35 [extracellular region] (Sus scrofa)
p-STAT4 dissociates from IL12RB2:IL12RB2 receptor (Sus scrofa)
IL35:(IL12RB2:p-JAK2) dimer [plasma membrane] (Sus scrofa)
IL35 [extracellular region] (Sus scrofa)
IL35:(IL12RB2:p-JAK2) dimer:p-STAT4 [plasma membrane] (Sus scrofa)
IL35:(IL12RB2:p-JAK2) dimer [plasma membrane] (Sus scrofa)
IL35 [extracellular region] (Sus scrofa)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
EBI3 [extracellular region]
(Sus scrofa)
IL12A [extracellular region]
(Sus scrofa)
Participates
as an input of
IL35 binds IL6ST:IL6ST receptor (Sus scrofa)
IL35 binds IL-12RB2:IL6ST receptor (Sus scrofa)
IL35 binds IL12RB2:IL12RB2 receptor (Sus scrofa)
IL35 binds IL27RA:IL12RB2 receptor (Sus scrofa)
as a component of
IL35:(IL6ST:p-JAK1:p-JAK2:p-TYK2) dimer [plasma membrane] (Sus scrofa)
IL-35:(IL6ST:JAK1:JAK2) dimer [plasma membrane] (Sus scrofa)
IL-35:(IL6ST:p-JAK1:p-JAK2) dimer [plasma membrane] (Sus scrofa)
IL35:IL6ST:JAK1:IL12RB2:JAK2 [plasma membrane] (Sus scrofa)
IL35:IL6ST:p-JAK1:IL12RB2:p-JAK2 [plasma membrane] (Sus scrofa)
IL35:(IL12RB2:JAK2 dimer) [plasma membrane] (Sus scrofa)
IL35:(IL12RB2:p-JAK2) dimer [plasma membrane] (Sus scrofa)
IL12A:EBI3:IL12RB2:p-JAK1:IL27RA:p-JAK2 [plasma membrane] (Sus scrofa)
IL35:IL27RA:p-JAK1:IL12RB2:p-JAK2 [plasma membrane] (Sus scrofa)
IL35:IL27RA:JAK1:IL12RB2:JAK2 [plasma membrane] (Sus scrofa)
as an output of
Interleukin-35 translocates from the ER lumen to the extracellular region (Sus scrofa)
Inferred From
IL35 [extracellular region]
(Homo sapiens)
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