Reactome | AREG [ER to Golgi transport vesicle membrane]

AREG [ER to Golgi transport vesicle membrane]

Stable Identifier

R-SSC-5689771

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

ER to Golgi transport vesicle membrane

Synonyms

AREG precursor, Q9BDH4

Locations in the PathwayBrowser

Expand all

Metabolism of proteins (Sus scrofa)

- Post-translational protein modification (Sus scrofa)
  - Asparagine N-linked glycosylation (Sus scrofa)
    - Transport to the Golgi and subsequent modification (Sus scrofa)
      - ER to Golgi Anterograde Transport (Sus scrofa)
        
        COPII-mediated vesicle transport (Sus scrofa)
        
        BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle (Sus scrofa)
        
        COPII cargo:receptors:v:SNAREs:GOLGA2:GORASP1:USO1 homodimer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Sus scrofa)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        CNIH1:TFGA,AREG precursors [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        TFGA, AREG precursors [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        AREG [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        Nucleotide exchange on RAB1 (Sus scrofa)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Sus scrofa)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        CNIH1:TFGA,AREG precursors [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        TFGA, AREG precursors [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        AREG [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Sus scrofa)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        CNIH1:TFGA,AREG precursors [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        TFGA, AREG precursors [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        AREG [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        RAB1:GTP binds USO1 and GORASP1:GOLGA2 (Sus scrofa)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Sus scrofa)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        CNIH1:TFGA,AREG precursors [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        TFGA, AREG precursors [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        AREG [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Sus scrofa)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Sus scrofa)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        CNIH1:TFGA,AREG precursors [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        TFGA, AREG precursors [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        AREG [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        Vesicle budding (Sus scrofa)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        CNIH1:TFGA,AREG precursors [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        TFGA, AREG precursors [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        AREG [ER to Golgi transport vesicle membrane] (Sus scrofa)

Vesicle-mediated transport (Sus scrofa)

- Membrane Trafficking (Sus scrofa)
  - ER to Golgi Anterograde Transport (Sus scrofa)
    - COPII-mediated vesicle transport (Sus scrofa)
      - BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle (Sus scrofa)
        
        COPII cargo:receptors:v:SNAREs:GOLGA2:GORASP1:USO1 homodimer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Sus scrofa)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        CNIH1:TFGA,AREG precursors [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        TFGA, AREG precursors [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        AREG [ER to Golgi transport vesicle membrane] (Sus scrofa)
      - Nucleotide exchange on RAB1 (Sus scrofa)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Sus scrofa)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        CNIH1:TFGA,AREG precursors [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        TFGA, AREG precursors [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        AREG [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Sus scrofa)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        CNIH1:TFGA,AREG precursors [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        TFGA, AREG precursors [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        AREG [ER to Golgi transport vesicle membrane] (Sus scrofa)
      - RAB1:GTP binds USO1 and GORASP1:GOLGA2 (Sus scrofa)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Sus scrofa)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        CNIH1:TFGA,AREG precursors [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        TFGA, AREG precursors [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        AREG [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Sus scrofa)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Sus scrofa)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        CNIH1:TFGA,AREG precursors [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        TFGA, AREG precursors [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        AREG [ER to Golgi transport vesicle membrane] (Sus scrofa)
      - Vesicle budding (Sus scrofa)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        CNIH1:TFGA,AREG precursors [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        TFGA, AREG precursors [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        AREG [ER to Golgi transport vesicle membrane] (Sus scrofa)

External Reference Information

External Reference

UniProt:Q9BDH4

Gene Names

AREG

Reference Genes

BioGPS Gene:397668 AREG

ENSEMBL:ENSSSCG00000008963.4

KEGG:ssc:397668 AREG

Monarch:397668 AREG

NCBI Gene:397668 AREG

UCSC:Q9BDH4 AREG

Reference Transcript

RefSeq:NM_214376.1 AREG

Other Identifiers

397668

GO:0005102

GO:0005154

GO:0005576

GO:0005615

GO:0005634

GO:0005737

GO:0007165

GO:0007173

GO:0007186

GO:0008083

GO:0008284

GO:0009986

GO:0016020

GO:0022414

GO:0023052

GO:0030297

GO:0032355

GO:0036211

GO:0038134

GO:0043226

GO:0048018

GO:0048856

GO:0050731

GO:0060598

GO:0060744

GO:0060749

GO:0060750

GO:0098772

Ssc.14467.2.S1_a_at

Participates

as a member of

TFGA, AREG precursors [ER to Golgi transport vesicle membrane] (Sus scrofa)

Other forms of this molecule

AREG [clathrin-coated endocytic vesicle membrane]

AREG [endoplasmic reticulum-Golgi intermediate compartment membrane]

AREG [endoplasmic reticulum membrane]

AREG [extracellular region]

Inferred From

AREG precursor [ER to Golgi transport vesicle membrane] (Homo sapiens)

Cross References

RefSeq

NP_999541.1

ENSEMBL

ENSSSCT00000009818, ENSSSCP00000009565, ENSSSCG00000008963

VGNC

85444

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