Reactome | phospho-HIST1H3E [nucleoplasm]

phospho-HIST1H3E [nucleoplasm]

Stable Identifier

R-SSC-5625859

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

nucleoplasm

Synonyms

p-T12,MeK-10-HIST1H3A, F1RVA0

Locations in the PathwayBrowser

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Signal Transduction (Sus scrofa)

- Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Sus scrofa)
  - Signaling by Rho GTPases (Sus scrofa)
    - RHO GTPase Effectors (Sus scrofa)
      - RHO GTPases activate PKNs (Sus scrofa)
        
        Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 (Sus scrofa)
        
        KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters (Sus scrofa)
        
        p-T774-PKN1:AR:Androgen:KLK2,KLK3 Gene:Nucleosome with p-T12,MeK-10-H3:KDM1A [nucleoplasm] (Sus scrofa)
        
        p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12,MeK-10-H3 [nucleoplasm] (Sus scrofa)
        
        Nucleosome with p-T12, MeK-10-H3 [nucleoplasm] (Sus scrofa)
        
        p-T12,MeK-10-H3 [nucleoplasm] (Sus scrofa)
        
        phospho-HIST1H3E [nucleoplasm] (Sus scrofa)
        
        KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters (Sus scrofa)
        
        p-T774-PKN1:AR:Androgen:KLK2,KLK3 Gene:Nucleosome with p-T12,MeK-10-H3:KDM1A [nucleoplasm] (Sus scrofa)
        
        p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12,MeK-10-H3 [nucleoplasm] (Sus scrofa)
        
        Nucleosome with p-T12, MeK-10-H3 [nucleoplasm] (Sus scrofa)
        
        p-T12,MeK-10-H3 [nucleoplasm] (Sus scrofa)
        
        phospho-HIST1H3E [nucleoplasm] (Sus scrofa)

External Reference Information

External Reference

UniProt:F1RVA0

Gene Names

HIST1H3E

Reference Genes

BioGPS Gene:100154511 HIST1H3E

BioGPS Gene:106504121 HIST1H3E

ENSEMBL:ENSSSCG00000052704.1 HIST1H3E

ENSEMBL:ENSSSCG00000053072.1 HIST1H3E

ENSEMBL:ENSSSCG00000056496.1 HIST1H3E

ENSEMBL:ENSSSCG00000059210.1

ENSEMBL:ENSSSCG00000060961.1 HIST1H3E

ENSEMBL:ENSSSCG00000061876.1 HIST1H3E

KEGG Gene (Sus scrofa):100154511 HIST1H3E

KEGG Gene (Sus scrofa):106504121 HIST1H3E

Monarch:100154511 HIST1H3E

Monarch:106504121 HIST1H3E

NCBI Gene:100154511 HIST1H3E

NCBI Gene:106504121 HIST1H3E

Reference Transcript

Other Identifiers

100154511

106504121

110261664

GO:0000786

GO:0003677

GO:0005198

GO:0005634

GO:0005654

GO:0005694

GO:0006325

GO:0006334

GO:0010467

GO:0030527

GO:0032991

GO:0040029

GO:0043226

GO:0046982

GO:0065003

Participates

as a member of

p-T12,MeK-10-H3 [nucleoplasm] (Sus scrofa)

Other forms of this molecule

HIST1H3E [nucleoplasm]

phospho-HIST1H3E [nucleoplasm]

HIST1H3E [nucleoplasm]

HIST1H3E [cytosol]

HIST1H3E [nucleoplasm]

phospho-HIST1H3E [nucleoplasm]

HIST1H3E [nucleoplasm]

Inferred From

p-T12,MeK-10-HIST1H3A [nucleoplasm] (Homo sapiens)

Modified Residues

Name

N6-methyl-L-lysine at 10 (in Homo sapiens)

Coordinate

PsiMod Name

N6-methyl-L-lysine [MOD:00085]

PsiMod Definition

A protein modification that effectively converts an L-lysine residue to N6-methyl-L-lysine.

Name

O-phospho-L-threonine at 12 (in Homo sapiens)

Coordinate

PsiMod Name

O-phospho-L-threonine [MOD:00047]

PsiMod Definition

A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.

Cross References

RefSeq

NP_001274345.1, XP_013844399.1

Ensembl

ENSSSCG00000061876, ENSSSCT00000093155, ENSSSCG00000060961, ENSSSCP00000075397, ENSSSCP00000080818, ENSSSCT00000103518, ENSSSCG00000052704, ENSSSCT00000093227, ENSSSCP00000076483, ENSSSCP00000080899, ENSSSCT00000096945, ENSSSCP00000080631, ENSSSCG00000056496, ENSSSCP00000080830, ENSSSCG00000053072, ENSSSCG00000059210, ENSSSCT00000100037, ENSSSCT00000097116

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