Reactome | TAS1R2 [plasma membrane]

TAS1R2 [plasma membrane]

Stable Identifier

R-SSC-444622

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

plasma membrane

Synonyms

TAS1R2, A0A287AFV6

Locations in the PathwayBrowser

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Sensory Perception (Sus scrofa)

- Sensory perception of taste (Sus scrofa)
  - Sensory perception of sweet, bitter, and umami (glutamate) taste (Sus scrofa)
    - Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) (Sus scrofa)
      - TAS1R2:TAS1R3:GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Sus scrofa)
        
        TAS1R2:TAS1R3 [plasma membrane] (Sus scrofa)
        
        TAS1R2 [plasma membrane] (Sus scrofa)
      - TAS1R2:TAS1R3:Sweet compound:GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Sus scrofa)
        
        TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Sus scrofa)
        
        TAS1R2:TAS1R3 [plasma membrane] (Sus scrofa)
        
        TAS1R2 [plasma membrane] (Sus scrofa)

Signal Transduction (Sus scrofa)

- Signaling by GPCR (Sus scrofa)
  - GPCR downstream signalling (Sus scrofa)
    - G alpha (i) signalling events (Sus scrofa)
      - Liganded Gi-activating GPCR acts as a GEF for Gi (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Sus scrofa)
        
        TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Sus scrofa)
        
        TAS1R2:TAS1R3 [plasma membrane] (Sus scrofa)
        
        TAS1R2 [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Sus scrofa)
        
        TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Sus scrofa)
        
        TAS1R2:TAS1R3 [plasma membrane] (Sus scrofa)
        
        TAS1R2 [plasma membrane] (Sus scrofa)
  - GPCR ligand binding (Sus scrofa)
    - Class C/3 (Metabotropic glutamate/pheromone receptors) (Sus scrofa)
      - T1R2/T1R3 dimer is a sweet taste receptor (Sus scrofa)
        
        TAS1R2:TAS1R3 [plasma membrane] (Sus scrofa)
        
        TAS1R2 [plasma membrane] (Sus scrofa)
        
        TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Sus scrofa)
        
        TAS1R2:TAS1R3 [plasma membrane] (Sus scrofa)
        
        TAS1R2 [plasma membrane] (Sus scrofa)

External Reference Information

External Reference

UniProt:A0A287AFV6

Gene Names

TAS1R2

Reference Genes

BioGPS Gene:100913086 TAS1R2

ENSEMBL:ENSSSCG00000039973.1

Monarch:100913086 TAS1R2

NCBI Gene:100913086 TAS1R2

UCSC:A0A287AFV6 TAS1R2

Reference Transcript

RefSeq:XM_021093444.1 TAS1R2

Other Identifiers

100913086

GO:0001582

GO:0004888

GO:0004930

GO:0005886

GO:0007165

GO:0007186

GO:0008527

GO:0016020

GO:0032467

GO:0033041

GO:0043235

GO:0050877

GO:0050909

GO:0050916

GO:1903767

Participates

as a component of

TAS1R2:TAS1R3 [plasma membrane] (Sus scrofa)

Inferred From

TAS1R2 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

XP_020949103.1

ENSEMBL

ENSSSCG00000039973, ENSSSCP00000042780, ENSSSCT00000060794

VGNC

93741

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