Reactome | FFAR4 [plasma membrane]

FFAR4 [plasma membrane]

Stable Identifier

R-SSC-400502

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

plasma membrane

Synonyms

FFAR4, E7EDN1

Locations in the PathwayBrowser

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Signal Transduction (Sus scrofa)

- Signaling by GPCR (Sus scrofa)
  - GPCR downstream signalling (Sus scrofa)
    - G alpha (q) signalling events (Sus scrofa)
      - Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Sus scrofa)
        
        FFAR4:FFAR4 ligands [plasma membrane] (Sus scrofa)
        
        FFAR4 [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Sus scrofa)
        
        FFAR4:FFAR4 ligands [plasma membrane] (Sus scrofa)
        
        FFAR4 [plasma membrane] (Sus scrofa)
      - Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Sus scrofa)
        
        FFAR4:FFAR4 ligands [plasma membrane] (Sus scrofa)
        
        FFAR4 [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Sus scrofa)
        
        FFAR4:FFAR4 ligands [plasma membrane] (Sus scrofa)
        
        FFAR4 [plasma membrane] (Sus scrofa)
      - The Ligand:GPCR:Gq complex dissociates (Sus scrofa)
        
        GPCRs that activate Gq/11 [plasma membrane] (Sus scrofa)
        
        FFAR4 [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Sus scrofa)
        
        FFAR4:FFAR4 ligands [plasma membrane] (Sus scrofa)
        
        FFAR4 [plasma membrane] (Sus scrofa)

External Reference Information

External Reference

UniProt:E7EDN1

Gene Names

FFAR4

Reference Genes

BioGPS Gene:116183081 FFAR4

ENSEMBL:ENSSSCG00000010478.5

ENSEMBL:ENSSSCG00005016626.1 FFAR4

KEGG Gene (Sus scrofa):100135678 FFAR4

Monarch:116183081 FFAR4

NCBI Gene:116183081 FFAR4

Reference Transcript

RefSeq:NM_001204766.1 FFAR4

Other Identifiers

116183081

GO:0001818

GO:0004930

GO:0005504

GO:0005886

GO:0005929

GO:0006954

GO:0007186

GO:0007200

GO:0007204

GO:0008289

GO:0008527

GO:0010827

GO:0012501

GO:0016020

GO:0023052

GO:0030139

GO:0030154

GO:0031410

GO:0032691

GO:0032870

GO:0036321

GO:0042277

GO:0043066

GO:0043226

GO:0043950

GO:0045444

GO:0045669

GO:0046879

GO:0050728

GO:0050872

GO:0050873

GO:0050877

GO:0050912

GO:0055085

GO:0060089

GO:0070094

GO:0070374

GO:0090275

GO:0090336

GO:0120162

Ssc.9938.1.A1_at

Participates

as a member of

GPCRs that activate Gq/11 [plasma membrane] (Sus scrofa)

as a component of

FFAR4:FFAR4 ligands [plasma membrane] (Sus scrofa)

Inferred From

FFAR4 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_001191695.1

OpenTargets

ENSG00000186188

Ensembl

ENSSSCG00000010478, ENSSSCT00000054114, ENSSSCP00000059157

VGNC

107392