Reactome | GRPR [plasma membrane]

GRPR [plasma membrane]

Stable Identifier

R-SSC-375363

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

plasma membrane

Synonyms

GRPR, K7GR81

Locations in the PathwayBrowser

Expand all

Signal Transduction (Sus scrofa)

- Signaling by GPCR (Sus scrofa)
  - GPCR downstream signalling (Sus scrofa)
    - G alpha (q) signalling events (Sus scrofa)
      - Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Sus scrofa)
        
        Bombesin-like receptor:bombesin-like peptide [plasma membrane] (Sus scrofa)
        
        Bombesin-like receptor [plasma membrane] (Sus scrofa)
        
        GRPR [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Sus scrofa)
        
        Bombesin-like receptor:bombesin-like peptide [plasma membrane] (Sus scrofa)
        
        Bombesin-like receptor [plasma membrane] (Sus scrofa)
        
        GRPR [plasma membrane] (Sus scrofa)
      - Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Sus scrofa)
        
        Bombesin-like receptor:bombesin-like peptide [plasma membrane] (Sus scrofa)
        
        Bombesin-like receptor [plasma membrane] (Sus scrofa)
        
        GRPR [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Sus scrofa)
        
        Bombesin-like receptor:bombesin-like peptide [plasma membrane] (Sus scrofa)
        
        Bombesin-like receptor [plasma membrane] (Sus scrofa)
        
        GRPR [plasma membrane] (Sus scrofa)
      - The Ligand:GPCR:Gq complex dissociates (Sus scrofa)
        
        GPCRs that activate Gq/11 [plasma membrane] (Sus scrofa)
        
        Bombesin-like receptor [plasma membrane] (Sus scrofa)
        
        GRPR [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Sus scrofa)
        
        Bombesin-like receptor:bombesin-like peptide [plasma membrane] (Sus scrofa)
        
        Bombesin-like receptor [plasma membrane] (Sus scrofa)
        
        GRPR [plasma membrane] (Sus scrofa)
  - GPCR ligand binding (Sus scrofa)
    - Class A/1 (Rhodopsin-like receptors) (Sus scrofa)
      - Peptide ligand-binding receptors (Sus scrofa)
        
        Bombesin-like receptors bind bombesin homologues (Sus scrofa)
        
        Bombesin-like receptor [plasma membrane] (Sus scrofa)
        
        GRPR [plasma membrane] (Sus scrofa)
        
        Bombesin-like receptor:bombesin-like peptide [plasma membrane] (Sus scrofa)
        
        Bombesin-like receptor [plasma membrane] (Sus scrofa)
        
        GRPR [plasma membrane] (Sus scrofa)

External Reference Information

External Reference

UniProt:K7GR81

Gene Names

GRPR

Reference Genes

BioGPS Gene:100517439 GRPR

ENSEMBL:ENSSSCG00000012144.6

KEGG Gene (Sus scrofa):100517439 GRPR

Monarch:100517439 GRPR

NCBI Gene:100517439 GRPR

Reference Transcript

RefSeq:NM_001315640.1 GRPR

Other Identifiers

100517439

GO:0004930

GO:0005886

GO:0007165

GO:0007186

GO:0007200

GO:0007218

GO:0008188

GO:0008528

GO:0016020

GO:0023052

GO:0035176

GO:0036343

GO:0042127

GO:0043207

GO:0060089

GO:0061744

GO:1903942

GO:2000987

Participates

as a member of

Bombesin-like receptor [plasma membrane] (Sus scrofa)

Inferred From

GRPR [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_001302569.1

OpenTargets

ENSG00000126010

Ensembl

ENSSSCP00000012927, ENSSSCT00000013283, ENSSSCG00000012144