Reactome | ACKR3 [plasma membrane]

ACKR3 [plasma membrane]

Stable Identifier

R-SSC-373859

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

plasma membrane

Synonyms

CXCR7, F1SM08

Locations in the PathwayBrowser

Expand all

Signal Transduction (Sus scrofa)

- Signaling by GPCR (Sus scrofa)
  - GPCR downstream signalling (Sus scrofa)
    - G alpha (i) signalling events (Sus scrofa)
      - Liganded Gi-activating GPCR acts as a GEF for Gi (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Sus scrofa)
        
        CXCR4,7:CXCL12 [plasma membrane] (Sus scrofa)
        
        CXCR4,7 [plasma membrane] (Sus scrofa)
        
        ACKR3 [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Sus scrofa)
        
        CXCR4,7:CXCL12 [plasma membrane] (Sus scrofa)
        
        CXCR4,7 [plasma membrane] (Sus scrofa)
        
        ACKR3 [plasma membrane] (Sus scrofa)
  - GPCR ligand binding (Sus scrofa)
    - Class A/1 (Rhodopsin-like receptors) (Sus scrofa)
      - Peptide ligand-binding receptors (Sus scrofa)
        
        Chemokine receptors bind chemokines (Sus scrofa)
        
        Receptors CXCR4 and 7 bind CXCL12 ligand (Sus scrofa)
        
        CXCR4,7 [plasma membrane] (Sus scrofa)
        
        ACKR3 [plasma membrane] (Sus scrofa)
        
        CXCR4,7:CXCL12 [plasma membrane] (Sus scrofa)
        
        CXCR4,7 [plasma membrane] (Sus scrofa)
        
        ACKR3 [plasma membrane] (Sus scrofa)

External Reference Information

External Reference

UniProt:F1SM08

Gene Names

ACKR3

Reference Genes

BioGPS Gene:100515346 ACKR3

ENSEMBL:ENSSSCG00005009789.1

KEGG:ssc:100515346 ACKR3

Monarch:100515346 ACKR3

NCBI Gene:100515346 ACKR3

UCSC:F1SM08 ACKR3

Reference Transcript

RefSeq:XM_003133759.4 ACKR3

Other Identifiers

100515346

GO:0001525

GO:0001570

GO:0002376

GO:0004930

GO:0005044

GO:0005768

GO:0005886

GO:0005905

GO:0006935

GO:0006955

GO:0007165

GO:0007186

GO:0007204

GO:0008285

GO:0009897

GO:0009986

GO:0015026

GO:0016020

GO:0016192

GO:0016493

GO:0016494

GO:0019722

GO:0019956

GO:0019957

GO:0019958

GO:0021557

GO:0030154

GO:0031623

GO:0038024

GO:0048856

GO:0048870

GO:0060326

GO:0070098

GO:0070374

GO:1902230

Ssc.28673.1.S1_at

Participates

as a member of

CXCR4,7 [plasma membrane] (Sus scrofa)

Inferred From

CXCR7 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

XP_003133807.1

ENSEMBL

ENSSSCT00000017775, ENSSSCP00000017294, ENSSSCG00000016322

VGNC

96017

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