Reactome | TAS2R3 [plasma membrane]

TAS2R3 [plasma membrane]

Stable Identifier

R-SSC-3299621

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

plasma membrane

Synonyms

TAS2R3, I3LF46

Locations in the PathwayBrowser

Expand all

Sensory Perception (Sus scrofa)

- Sensory perception of taste (Sus scrofa)
  - Sensory perception of sweet, bitter, and umami (glutamate) taste (Sus scrofa)
    - Bitter compound binds bitter taste receptor (TAS2R) (Sus scrofa)
      - TAS2R:GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Sus scrofa)
        
        TAS2R (non-orphan) [plasma membrane] (Sus scrofa)
        
        TAS2R3 [plasma membrane] (Sus scrofa)
      - TAS2R:ligand:GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Sus scrofa)
        
        TAS2R (non-orphan):ligand [plasma membrane] (Sus scrofa)
        
        TAS2R3:ligand [plasma membrane] (Sus scrofa)
        
        TAS2R3 [plasma membrane] (Sus scrofa)

Signal Transduction (Sus scrofa)

- Signaling by GPCR (Sus scrofa)
  - GPCR downstream signalling (Sus scrofa)
    - G alpha (i) signalling events (Sus scrofa)
      - Liganded Gi-activating GPCR acts as a GEF for Gi (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Sus scrofa)
        
        TAS2Rs:Bitter-tasting compounds [plasma membrane] (Sus scrofa)
        
        TAS2Rs [plasma membrane] (Sus scrofa)
        
        TAS2R3 [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Sus scrofa)
        
        TAS2Rs:Bitter-tasting compounds [plasma membrane] (Sus scrofa)
        
        TAS2Rs [plasma membrane] (Sus scrofa)
        
        TAS2R3 [plasma membrane] (Sus scrofa)
      - Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Sus scrofa)
        
        TAS2Rs:Bitter-tasting compounds [plasma membrane] (Sus scrofa)
        
        TAS2Rs [plasma membrane] (Sus scrofa)
        
        TAS2R3 [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Sus scrofa)
        
        TAS2Rs:Bitter-tasting compounds [plasma membrane] (Sus scrofa)
        
        TAS2Rs [plasma membrane] (Sus scrofa)
        
        TAS2R3 [plasma membrane] (Sus scrofa)
      - The Ligand:GPCR:Gi complex dissociates (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Sus scrofa)
        
        TAS2Rs:Bitter-tasting compounds [plasma membrane] (Sus scrofa)
        
        TAS2Rs [plasma membrane] (Sus scrofa)
        
        TAS2R3 [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Sus scrofa)
        
        TAS2Rs:Bitter-tasting compounds [plasma membrane] (Sus scrofa)
        
        TAS2Rs [plasma membrane] (Sus scrofa)
        
        TAS2R3 [plasma membrane] (Sus scrofa)
  - GPCR ligand binding (Sus scrofa)
    - Class C/3 (Metabotropic glutamate/pheromone receptors) (Sus scrofa)
      - T2Rs bind bitter-tasting compounds (Sus scrofa)
        
        TAS2Rs [plasma membrane] (Sus scrofa)
        
        TAS2R3 [plasma membrane] (Sus scrofa)
        
        TAS2Rs:Bitter-tasting compounds [plasma membrane] (Sus scrofa)
        
        TAS2Rs [plasma membrane] (Sus scrofa)
        
        TAS2R3 [plasma membrane] (Sus scrofa)

External Reference Information

External Reference

UniProt:I3LF46

Gene Names

TAS2R3

Reference Genes

ENSEMBL:ENSSSCG00000028394.2

Other Identifiers

100621051

GO:0001580

GO:0004930

GO:0007165

GO:0007186

GO:0016020

GO:0023052

GO:0033038

GO:0050877

GO:0050896

GO:0050909

GO:0060089

Participates

as a member of

as a component of

TAS2R3:ligand [plasma membrane] (Sus scrofa)

Inferred From

TAS2R3 [plasma membrane] (Homo sapiens)

Cross References

OpenTargets

ENSG00000127362

Ensembl

ENSSSCP00000022686, ENSSSCT00000030179, ENSSSCG00000028394

VGNC

93744