Reactome | TAS2R4 [plasma membrane]

TAS2R4 [plasma membrane]

Stable Identifier

R-SSC-3299613

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

plasma membrane

Synonyms

TAS2R4, I3LE78

Locations in the PathwayBrowser

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Sensory Perception (Sus scrofa)

- Sensory perception of taste (Sus scrofa)
  - Sensory perception of sweet, bitter, and umami (glutamate) taste (Sus scrofa)
    - Bitter compound binds bitter taste receptor (TAS2R) (Sus scrofa)
      - TAS2R:GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Sus scrofa)
        
        TAS2R (non-orphan) [plasma membrane] (Sus scrofa)
        
        TAS2R4 [plasma membrane] (Sus scrofa)
      - TAS2R:ligand:GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Sus scrofa)
        
        TAS2R (non-orphan):ligand [plasma membrane] (Sus scrofa)
        
        TAS2R4:ligand [plasma membrane] (Sus scrofa)
        
        TAS2R4 [plasma membrane] (Sus scrofa)

Signal Transduction (Sus scrofa)

- Signaling by GPCR (Sus scrofa)
  - GPCR downstream signalling (Sus scrofa)
    - G alpha (i) signalling events (Sus scrofa)
      - Liganded Gi-activating GPCR acts as a GEF for Gi (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Sus scrofa)
        
        TAS2Rs:Bitter-tasting compounds [plasma membrane] (Sus scrofa)
        
        TAS2Rs [plasma membrane] (Sus scrofa)
        
        TAS2R4 [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Sus scrofa)
        
        TAS2Rs:Bitter-tasting compounds [plasma membrane] (Sus scrofa)
        
        TAS2Rs [plasma membrane] (Sus scrofa)
        
        TAS2R4 [plasma membrane] (Sus scrofa)
  - GPCR ligand binding (Sus scrofa)
    - Class C/3 (Metabotropic glutamate/pheromone receptors) (Sus scrofa)
      - T2Rs bind bitter-tasting compounds (Sus scrofa)
        
        TAS2Rs [plasma membrane] (Sus scrofa)
        
        TAS2R4 [plasma membrane] (Sus scrofa)
        
        TAS2Rs:Bitter-tasting compounds [plasma membrane] (Sus scrofa)
        
        TAS2Rs [plasma membrane] (Sus scrofa)
        
        TAS2R4 [plasma membrane] (Sus scrofa)

External Reference Information

External Reference

UniProt:I3LE78

Gene Names

TAS2R4

Reference Genes

BioGPS Gene:100620853 TAS2R4

ENSEMBL:ENSSSCG00000021525.2

KEGG:ssc:100620853 TAS2R4

Monarch:100620853 TAS2R4

NCBI Gene:100620853 TAS2R4

UCSC:I3LE78 TAS2R4

Reference Transcript

RefSeq:XM_021078593.1 TAS2R4

Other Identifiers

100620853

GO:0001580

GO:0004930

GO:0007165

GO:0007186

GO:0007585

GO:0016020

GO:0033038

GO:0050877

GO:0050909

Participates

as a member of

as a component of

TAS2R4:ligand [plasma membrane] (Sus scrofa)

Inferred From

TAS2R4 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

XP_020934252.1

ENSEMBL

ENSSSCT00000023151, ENSSSCG00000021525, ENSSSCP00000022364

VGNC

93746

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