Reactome | DNAJC6 [cytosol]

DNAJC6 [cytosol]

Stable Identifier

R-SSC-264472

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

cytosol

Synonyms

DNAJC6, A0A480ZET4

Locations in the PathwayBrowser

Expand all

Vesicle-mediated transport (Sus scrofa)

- Membrane Trafficking (Sus scrofa)
  - Clathrin-mediated endocytosis (Sus scrofa)
    - Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle (Sus scrofa)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        GAK,DNAJC6 [cytosol] (Sus scrofa)
        
        DNAJC6 [cytosol] (Sus scrofa)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        GAK,DNAJC6 [cytosol] (Sus scrofa)
        
        DNAJC6 [cytosol] (Sus scrofa)
    - Clathrin recruits auxilins to the clathrin-coated vesicle (Sus scrofa)
      - GAK,DNAJC6 [cytosol] (Sus scrofa)
        
        DNAJC6 [cytosol] (Sus scrofa)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        GAK,DNAJC6 [cytosol] (Sus scrofa)
        
        DNAJC6 [cytosol] (Sus scrofa)
    - HSPA8-mediated ATP hydrolysis promotes vesicle uncoating (Sus scrofa)
      - PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        GAK,DNAJC6 [cytosol] (Sus scrofa)
        
        DNAJC6 [cytosol] (Sus scrofa)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        GAK,DNAJC6 [cytosol] (Sus scrofa)
        
        DNAJC6 [cytosol] (Sus scrofa)
    - RAB5 and GAPVD1 bind AP-2 (Sus scrofa)
      - PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        GAK,DNAJC6 [cytosol] (Sus scrofa)
        
        DNAJC6 [cytosol] (Sus scrofa)

External Reference Information

External Reference

UniProt:A0A480ZET4

Gene Names

DNAJC6

Reference Genes

BioGPS Gene:406190 DNAJC6

ENSEMBL:ENSSSCG00000003807.4

Monarch:406190 DNAJC6

NCBI Gene:406190 DNAJC6

UCSC:A0A480ZET4 DNAJC6

Reference Transcript

RefSeq:XM_005656152.3 DNAJC6

Other Identifiers

406190

GO:0003824

GO:0004721

GO:0005737

GO:0014069

GO:0016191

GO:0016192

GO:0016311

GO:0016787

GO:0017124

GO:0030136

GO:0030276

GO:0031410

GO:0031982

GO:0036465

GO:0043226

GO:0045202

GO:0072318

GO:0072583

GO:0098793

GO:0098894

GO:0140096

GO:1905443

GO:2000369

Ssc.8233.1.A1_at

Participates

as a component of

HSC70:Auxillin Complex [cytosol] (Sus scrofa)

as a member of

GAK,DNAJC6 [cytosol] (Sus scrofa)

Inferred From

DNAJC6 [cytosol] (Homo sapiens)

Cross References

RefSeq

XP_005656209.1

ENSEMBL

ENSSSCP00000044192, ENSSSCT00000043320, ENSSSCG00000003807