Reactome | DSP [plasma membrane]

DSP [plasma membrane]

Stable Identifier

R-SSC-201580

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

plasma membrane

Synonyms

DSP, F1RW75

Locations in the PathwayBrowser

Expand all

Developmental Biology (Sus scrofa)

- Keratinization (Sus scrofa)
  - Formation of the cornified envelope (Sus scrofa)
    - CASP14 cleaves filaggrin (Sus scrofa)
      - Late cornified envelope [plasma membrane] (Sus scrofa)
        
        Cornified envelope:CDSN [plasma membrane] (Sus scrofa)
        
        Cornified envelope [plasma membrane] (Sus scrofa)
        
        Early cornified envelope [plasma membrane] (Sus scrofa)
        
        FLG-Keratin filament network [plasma membrane] (Sus scrofa)
        
        FLG(?-?):Keratin tonofilament:Desmosome [plasma membrane] (Sus scrofa)
        
        Keratin tonofilament:Desmosome [plasma membrane] (Sus scrofa)
        
        Desmosome [plasma membrane] (Sus scrofa)
        
        DSP [plasma membrane] (Sus scrofa)
      - Mature cornified envelope [plasma membrane] (Sus scrofa)
        
        No FGN-cornified envelope:CDSN [plasma membrane] (Sus scrofa)
        
        No FGN-Cornified envelope [plasma membrane] (Sus scrofa)
        
        No FGN-late cornified envelope [plasma membrane] (Sus scrofa)
        
        Keratin tonofilament:Desmosome network [plasma membrane] (Sus scrofa)
        
        Keratin tonofilament:Desmosome [plasma membrane] (Sus scrofa)
        
        Desmosome [plasma membrane] (Sus scrofa)
        
        DSP [plasma membrane] (Sus scrofa)
    - CDSN binds the cornified envelope (Sus scrofa)
      - Cornified envelope [plasma membrane] (Sus scrofa)
        
        Early cornified envelope [plasma membrane] (Sus scrofa)
        
        FLG-Keratin filament network [plasma membrane] (Sus scrofa)
        
        FLG(?-?):Keratin tonofilament:Desmosome [plasma membrane] (Sus scrofa)
        
        Keratin tonofilament:Desmosome [plasma membrane] (Sus scrofa)
        
        Desmosome [plasma membrane] (Sus scrofa)
        
        DSP [plasma membrane] (Sus scrofa)
      - Cornified envelope:CDSN [plasma membrane] (Sus scrofa)
        
        Cornified envelope [plasma membrane] (Sus scrofa)
        
        Early cornified envelope [plasma membrane] (Sus scrofa)
        
        FLG-Keratin filament network [plasma membrane] (Sus scrofa)
        
        FLG(?-?):Keratin tonofilament:Desmosome [plasma membrane] (Sus scrofa)
        
        Keratin tonofilament:Desmosome [plasma membrane] (Sus scrofa)
        
        Desmosome [plasma membrane] (Sus scrofa)
        
        DSP [plasma membrane] (Sus scrofa)
    - Filaggrin binds Keratin tonofilament:Desmosome (Sus scrofa)
      - FLG(?-?):Keratin tonofilament:Desmosome [plasma membrane] (Sus scrofa)
        
        Keratin tonofilament:Desmosome [plasma membrane] (Sus scrofa)
        
        Desmosome [plasma membrane] (Sus scrofa)
        
        DSP [plasma membrane] (Sus scrofa)
      - Keratin tonofilament:Desmosome [plasma membrane] (Sus scrofa)
        
        Desmosome [plasma membrane] (Sus scrofa)
        
        DSP [plasma membrane] (Sus scrofa)
    - Fillagrin and keratin intermediate filaments polymerize forming a network (Sus scrofa)
      - FLG(?-?):Keratin tonofilament:Desmosome [plasma membrane] (Sus scrofa)
        
        Keratin tonofilament:Desmosome [plasma membrane] (Sus scrofa)
        
        Desmosome [plasma membrane] (Sus scrofa)
        
        DSP [plasma membrane] (Sus scrofa)
      - FLG-Keratin filament network [plasma membrane] (Sus scrofa)
        
        FLG(?-?):Keratin tonofilament:Desmosome [plasma membrane] (Sus scrofa)
        
        Keratin tonofilament:Desmosome [plasma membrane] (Sus scrofa)
        
        Desmosome [plasma membrane] (Sus scrofa)
        
        DSP [plasma membrane] (Sus scrofa)
    - Lamellar bodies bind the early cornified envelope (Sus scrofa)
      - Cornified envelope [plasma membrane] (Sus scrofa)
        
        Early cornified envelope [plasma membrane] (Sus scrofa)
        
        FLG-Keratin filament network [plasma membrane] (Sus scrofa)
        
        FLG(?-?):Keratin tonofilament:Desmosome [plasma membrane] (Sus scrofa)
        
        Keratin tonofilament:Desmosome [plasma membrane] (Sus scrofa)
        
        Desmosome [plasma membrane] (Sus scrofa)
        
        DSP [plasma membrane] (Sus scrofa)
      - Early cornified envelope [plasma membrane] (Sus scrofa)
        
        FLG-Keratin filament network [plasma membrane] (Sus scrofa)
        
        FLG(?-?):Keratin tonofilament:Desmosome [plasma membrane] (Sus scrofa)
        
        Keratin tonofilament:Desmosome [plasma membrane] (Sus scrofa)
        
        Desmosome [plasma membrane] (Sus scrofa)
        
        DSP [plasma membrane] (Sus scrofa)
    - PERP binds desmosomes (Sus scrofa)
      - Desmosome [plasma membrane] (Sus scrofa)
        
        DSP [plasma membrane] (Sus scrofa)
      - Desmosome:PERP [plasma membrane] (Sus scrofa)
        
        Desmosome [plasma membrane] (Sus scrofa)
        
        DSP [plasma membrane] (Sus scrofa)
    - Plasma membrane resorption (Sus scrofa)
      - Mature cornified envelope [plasma membrane] (Sus scrofa)
        
        No FGN-cornified envelope:CDSN [plasma membrane] (Sus scrofa)
        
        No FGN-Cornified envelope [plasma membrane] (Sus scrofa)
        
        No FGN-late cornified envelope [plasma membrane] (Sus scrofa)
        
        Keratin tonofilament:Desmosome network [plasma membrane] (Sus scrofa)
        
        Keratin tonofilament:Desmosome [plasma membrane] (Sus scrofa)
        
        Desmosome [plasma membrane] (Sus scrofa)
        
        DSP [plasma membrane] (Sus scrofa)
  - Keratin filaments bind cell-cell adhesion complexes (Sus scrofa)
    - Desmosome [plasma membrane] (Sus scrofa)
      - DSP [plasma membrane] (Sus scrofa)
    - Keratin tonofilament:Desmosome [plasma membrane] (Sus scrofa)
      - Desmosome [plasma membrane] (Sus scrofa)
        
        DSP [plasma membrane] (Sus scrofa)

External Reference Information

External Reference

UniProt:F1RW75

Gene Names

DSP

Reference Genes

BioGPS Gene:100156744 DSP

ENSEMBL:ENSSSCG00000001025.5

KEGG:ssc:100156744 DSP

Monarch:100156744 DSP

NCBI Gene:100156744 DSP

UCSC:F1RW75 DSP

Reference Transcript

RefSeq:XM_003128168.4 DSP

Other Identifiers

GO:0001533

GO:0002934

GO:0003223

GO:0005080

GO:0005198

GO:0005515

GO:0005737

GO:0005856

GO:0005882

GO:0005886

GO:0005911

GO:0005912

GO:0007010

GO:0014704

GO:0016020

GO:0016323

GO:0030057

GO:0030154

GO:0030216

GO:0034330

GO:0034332

GO:0042060

GO:0043588

GO:0045104

GO:0045109

GO:0048856

GO:0070161

GO:0086073

GO:0086091

GO:0090136

GO:0097110

GO:0098609

GO:0098911

GO:0150105

Ssc.1623.1.S1_at

Ssc.27258.1.A1_at

Participates

as a candidate of

as a component of

Desmosome [plasma membrane] (Sus scrofa)

as a member of

Ficolin-rich granule membrane proteins [plasma membrane] (Sus scrofa)

as an input of

Caspase-mediated cleavage of Desmoplakin (Sus scrofa)

Other forms of this molecule

DSP [cornified envelope]

DSP [ficolin-1-rich granule membrane]

DSP [plasma membrane]

Inferred From

DSP [plasma membrane] (Homo sapiens)

Cross References

RefSeq

XP_003128216.2

ENSEMBL

ENSSSCG00000001025, ENSSSCT00000001118, ENSSSCP00000001096

VGNC

87459

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