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PTEN [cytosol]
Stable Identifier
R-SSC-199420
Type
Protein [EntityWithAccessionedSequence]
Species
Sus scrofa
Compartment
cytosol
Synonyms
PTEN, F2Z5H1
Locations in the PathwayBrowser
Expand all
Immune System (Sus scrofa)
Adaptive Immune System (Sus scrofa)
TCR signaling (Sus scrofa)
Downstream TCR signaling (Sus scrofa)
PTEN dephosphorylates PIP3 (Sus scrofa)
PTEN [cytosol] (Sus scrofa)
Metabolism (Sus scrofa)
Inositol phosphate metabolism (Sus scrofa)
Synthesis of IP3 and IP4 in the cytosol (Sus scrofa)
I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol (Sus scrofa)
PTEN:Mg2+ [cytosol] (Sus scrofa)
PTEN [cytosol] (Sus scrofa)
Metabolism of lipids (Sus scrofa)
Phospholipid metabolism (Sus scrofa)
PI Metabolism (Sus scrofa)
Synthesis of PIPs at the plasma membrane (Sus scrofa)
PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane (Sus scrofa)
PTEN [cytosol] (Sus scrofa)
PTEN dephosphorylates PIP3 (Sus scrofa)
PTEN [cytosol] (Sus scrofa)
Metabolism of proteins (Sus scrofa)
Post-translational protein modification (Sus scrofa)
Deubiquitination (Sus scrofa)
Ovarian tumor domain proteases (Sus scrofa)
OTUD3 deubiquitinates PTEN (Sus scrofa)
PTEN [cytosol] (Sus scrofa)
Signal Transduction (Sus scrofa)
Intracellular signaling by second messengers (Sus scrofa)
PIP3 activates AKT signaling (Sus scrofa)
Negative regulation of the PI3K/AKT network (Sus scrofa)
PTEN dephosphorylates PIP3 (Sus scrofa)
PTEN [cytosol] (Sus scrofa)
PTEN Regulation (Sus scrofa)
Regulation of PTEN localization (Sus scrofa)
Deubiquitinated PTEN translocates to the cytosol (Sus scrofa)
PTEN [cytosol] (Sus scrofa)
PTEN undergoes monoubiquitination (Sus scrofa)
PTEN [cytosol] (Sus scrofa)
Regulation of PTEN stability and activity (Sus scrofa)
Casein kinase II phosphorylates PTEN (Sus scrofa)
PTEN [cytosol] (Sus scrofa)
FRK phosphorylates PTEN (Sus scrofa)
PTEN:p-Y387-FRK [cytosol] (Sus scrofa)
PTEN [cytosol] (Sus scrofa)
MKRN1 polyubiquitinates PTEN (Sus scrofa)
PTEN [cytosol] (Sus scrofa)
NEDD4, WWP2, CHIP and XIAP polyubiquitinate PTEN (Sus scrofa)
PTEN [cytosol] (Sus scrofa)
PREX2 binds PTEN and inhibits it (Sus scrofa)
PREX2:PTEN,p-3S,2T-PTEN [cytosol] (Sus scrofa)
PTEN, p-3S,2T-PTEN [cytosol] (Sus scrofa)
PTEN [cytosol] (Sus scrofa)
PTEN, p-3S,2T-PTEN [cytosol] (Sus scrofa)
PTEN [cytosol] (Sus scrofa)
PTEN binds FRK (Sus scrofa)
PTEN [cytosol] (Sus scrofa)
PTEN:p-Y387-FRK [cytosol] (Sus scrofa)
PTEN [cytosol] (Sus scrofa)
TRIM27 binds PTEN (Sus scrofa)
PTEN [cytosol] (Sus scrofa)
PTEN:TRIM27 [cytosol] (Sus scrofa)
PTEN [cytosol] (Sus scrofa)
TRIM27 polyubiquitinates PTEN (Sus scrofa)
PTEN:TRIM27 [cytosol] (Sus scrofa)
PTEN [cytosol] (Sus scrofa)
USP13 and OTUD3 deubiquitinate PTEN (Sus scrofa)
PTEN [cytosol] (Sus scrofa)
External Reference Information
External Reference
UniProt:F2Z5H1
Gene Names
PTEN
Reference Genes
ENSEMBL:ENSSSCG00000010440.3
UCSC:F2Z5H1 PTEN
Other Identifiers
100156264
GO:0003824
GO:0004721
GO:0004725
GO:0005634
GO:0005737
GO:0005829
GO:0005886
GO:0006629
GO:0006915
GO:0007399
GO:0008285
GO:0009966
GO:0010604
GO:0010648
GO:0014069
GO:0016311
GO:0016314
GO:0016605
GO:0016787
GO:0016791
GO:0019899
GO:0023057
GO:0042995
GO:0043197
GO:0043226
GO:0043491
GO:0045202
GO:0045595
GO:0046856
GO:0048856
GO:0048870
GO:0051093
GO:0051129
GO:0051241
GO:0051726
GO:0051896
GO:0065008
GO:0140096
Ssc.7652.1.A1_at
Participates
as an output of
OTUD3 deubiquitinates PTEN (Sus scrofa)
USP13 and OTUD3 deubiquitinate PTEN (Sus scrofa)
Deubiquitinated PTEN translocates to the cytosol (Sus scrofa)
as a member of
PTEN, p-3S,2T-PTEN [cytosol] (Sus scrofa)
as an input of
MKRN1 polyubiquitinates PTEN (Sus scrofa)
PTEN binds FRK (Sus scrofa)
Casein kinase II phosphorylates PTEN (Sus scrofa)
TRIM27 binds PTEN (Sus scrofa)
NEDD4, WWP2, CHIP and XIAP polyubiquitinate PTEN (Sus scrofa)
PTEN undergoes monoubiquitination (Sus scrofa)
as a component of
PTEN:p-Y387-FRK [cytosol] (Sus scrofa)
PTEN:TRIM27 [cytosol] (Sus scrofa)
PTEN:Mg2+ [cytosol] (Sus scrofa)
Other forms of this molecule
PTEN [cytosol]
PTEN [nucleoplasm]
phospho-PTEN [cytosol]
phospho-PTEN [cytosol]
phospho-PTEN [cytosol]
phospho-PTEN [cytosol]
PTEN [cytosol]
PTEN [cytosol]
PTEN [cytosol]
PTEN [cytosol]
PTEN [nucleoplasm]
PTEN [nucleoplasm]
Inferred From
PTEN [cytosol]
(Homo sapiens)
Cross References
ENSEMBL
ENSSSCP00000011128
,
ENSSSCG00000010440
,
ENSSSCT00000011425
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