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PTEN [cytosol]
Stable Identifier
R-SSC-8948777
Type
Protein [EntityWithAccessionedSequence]
Species
Sus scrofa
Compartment
cytosol
Synonyms
K48polyUb-K289-PTEN, F2Z5H1
Locations in the PathwayBrowser
Expand all
Signal Transduction (Sus scrofa)
Intracellular signaling by second messengers (Sus scrofa)
PIP3 activates AKT signaling (Sus scrofa)
PTEN Regulation (Sus scrofa)
Regulation of PTEN stability and activity (Sus scrofa)
MKRN1 polyubiquitinates PTEN (Sus scrofa)
PTEN [cytosol] (Sus scrofa)
Proteasome degrades polyubiquitinated PTEN (Sus scrofa)
PolyUb-PTEN, K48polyUb-K289-PTEN, PolyUb-K324,K344,K349-RibC-E40,E150,D326-PTEN [cytosol] (Sus scrofa)
PTEN [cytosol] (Sus scrofa)
USP13 and OTUD3 deubiquitinate PTEN (Sus scrofa)
PTEN [cytosol] (Sus scrofa)
External Reference Information
External Reference
UniProt:F2Z5H1
Gene Names
PTEN
Reference Genes
ENSEMBL:ENSSSCG00000010440.3
Other Identifiers
100156264
GO:0003824
GO:0004725
GO:0005634
GO:0005829
GO:0005886
GO:0006629
GO:0008285
GO:0016311
GO:0016314
GO:0016787
GO:0016791
GO:0023052
GO:0042995
GO:0043226
GO:0043491
GO:0046856
GO:0048870
GO:0051896
GO:0052866
GO:0140096
Ssc.7652.1.A1_at
Participates
as a member of
PolyUb-PTEN, K48polyUb-K289-PTEN, PolyUb-K324,K344,K349-RibC-E40,E150,D326-PTEN [cytosol] (Sus scrofa)
as an output of
MKRN1 polyubiquitinates PTEN (Sus scrofa)
as an input of
USP13 and OTUD3 deubiquitinate PTEN (Sus scrofa)
Other forms of this molecule
PTEN [cytosol]
PTEN [nucleoplasm]
phospho-PTEN [cytosol]
phospho-PTEN [cytosol]
phospho-PTEN [cytosol]
phospho-PTEN [cytosol]
PTEN [cytosol]
PTEN [cytosol]
PTEN [cytosol]
PTEN [nucleoplasm]
PTEN [nucleoplasm]
PTEN [cytosol]
Inferred From
PolyUb-PTEN,K48polyUb-K289-PTEN [cytosol]
(Homo sapiens)
K48polyUb-K289-PTEN [cytosol]
(Homo sapiens)
Modified Residues
Name
ubiquitinylated lysine (K48polyUb [cytosol]) at 289 (in Homo sapiens)
Coordinate
289
Modification
K48polyUb [cytosol]
PsiMod Name
ubiquitinylated lysine [MOD:01148]
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin.
Cross References
OpenTargets
ENSG00000171862
Ensembl
ENSSSCG00000010440
,
ENSSSCP00000011128
,
ENSSSCT00000011425
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