CYP17A1 cleaves 17aHPREG to DHA

Stable Identifier
Reaction [transition]
Sus scrofa
Side chain cleavage of 17alpha-hydroxypregnenolone to yield DHA, 17alpha-hydroxyprenenolone + NADPH + H+ + O2 => DHA (dehydroepiandrostenedione) + NADP+ + H2O + acetaldehyde
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This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also:

Catalyst Activity

steroid 17-alpha-monooxygenase activity of CYP17A1 [endoplasmic reticulum membrane]

This event is regulated
Positively by
Inferred From
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