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phospho-p-Y55-SPRY2 [cytosol]
Stable Identifier
R-SSC-182950
Type
Protein [EntityWithAccessionedSequence]
Species
Sus scrofa
Compartment
cytosol
Synonyms
F1RP67
Locations in the PathwayBrowser
Expand all
Signal Transduction (Sus scrofa)
Signaling by Receptor Tyrosine Kinases (Sus scrofa)
Signaling by EGFR (Sus scrofa)
EGFR downregulation (Sus scrofa)
CBL binds and ubiquitinates phosphorylated Sprouty (Sus scrofa)
EGF-like ligands:p-6Y-EGFR:CBL:Ub-p-Y53/55-SPRY1/2 [plasma membrane] (Sus scrofa)
Ub-p-Y53/55-SPRY1/2 [cytosol] (Sus scrofa)
p-Y53/55-SPRY1/2 [cytosol] (Sus scrofa)
phospho-p-Y55-SPRY2 [cytosol] (Sus scrofa)
CBL ubiquitinates Sprouty (Sus scrofa)
EGF-like ligands:p-6Y-EGFR:CBL:Ub-p-Y53/55-SPRY1/2 [plasma membrane] (Sus scrofa)
Ub-p-Y53/55-SPRY1/2 [cytosol] (Sus scrofa)
p-Y53/55-SPRY1/2 [cytosol] (Sus scrofa)
phospho-p-Y55-SPRY2 [cytosol] (Sus scrofa)
EGF-like ligands:p-6Y-EGFR:CBL:p-Y53/55-SPRY1/2 [plasma membrane] (Sus scrofa)
p-Y53/55-SPRY1/2 [cytosol] (Sus scrofa)
phospho-p-Y55-SPRY2 [cytosol] (Sus scrofa)
Sprouty lures CBL away from EGFR (Sus scrofa)
phospho-p-Y55-SPRY2 [cytosol] (Sus scrofa)
External Reference Information
External Reference
UniProt:F1RP67
Reference Genes
BioGPS Gene:100157266
ENSEMBL:ENSSSCG00000009482.4
ENSEMBL:ENSSSCG00005029787.1
KEGG Gene (Sus scrofa):100157266
Monarch:100157266
NCBI Gene:100157266
Reference Transcript
RefSeq:XM_001927097.4
Participates
as an input of
Sprouty lures CBL away from EGFR (Sus scrofa)
as a member of
p-Y53/55-SPRY1/2 [cytosol] (Sus scrofa)
Other forms of this molecule
phospho-p-S111,S120-SPRY2 [cytosol]
phospho-p-S112,S115-SPRY2 [cytosol]
SPRY2 [cytosol]
phospho-p-S112,S121-SPRY2 [plasma membrane]
SPRY2 [plasma membrane]
phospho-p-Y55,Y227-SPRY2 [plasma membrane]
Inferred From
p-Y55-SPRY2 [cytosol]
(Homo sapiens)
Modified Residues
Name
O4'-phospho-L-tyrosine at 55 (in Homo sapiens)
Coordinate
55
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Cross References
RefSeq
XP_001927132.1
VGNC
93425
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