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Shelterin complex [nucleoplasm]
Stable Identifier
R-SSC-174898
Type
Complex
Species
Sus scrofa
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
Cell Cycle (Sus scrofa)
Chromosome Maintenance (Sus scrofa)
Telomere Maintenance (Sus scrofa)
Extension of Telomeres (Sus scrofa)
Telomere C-strand (Lagging Strand) Synthesis (Sus scrofa)
Disassociation of Processive Complex and Completed Telomere End (Sus scrofa)
Extended And Processed Telomere End [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
Processive complex loaded on telomere:ligated C-strand Okazaki fragments [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
Polymerase switching on the C-strand of the telomere (Sus scrofa)
Formation of Processive Complex on the C-strand of the telomere (Sus scrofa)
Processive complex loaded on telomere [nucleoplasm] (Sus scrofa)
RNA primer-DNA primer:G-strand extended telomere:PCNA [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
RNA primer-DNA primer:G-strand extended telomere:PCNA [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere (Sus scrofa)
RFC Heteropentamer:RNA primer-DNA primer:G-strand extended telomere end [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
RFC Heteropentamer:RNA primer-DNA primer:G-strand extended telomere end duplex:PCNA homotrimer [nucleoplasm] (Sus scrofa)
RFC Heteropentamer:RNA primer-DNA primer:G-strand extended telomere end [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
RFC binding displaces Pol Alpha on the C-strand of the telomere (Sus scrofa)
RFC Heteropentamer:RNA primer-DNA primer:G-strand extended telomere end [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
RNA primer:DNA primer:G-strand extended telomere:POLA:primase [nucleoplasm] (Sus scrofa)
RNA primer:G-strand extended telomere end:POLA:primase [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
RFC dissociates after sliding clamp formation on the C-strand of the telomere (Sus scrofa)
RFC Heteropentamer:RNA primer-DNA primer:G-strand extended telomere end duplex:PCNA homotrimer [nucleoplasm] (Sus scrofa)
RFC Heteropentamer:RNA primer-DNA primer:G-strand extended telomere end [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
RNA primer-DNA primer:G-strand extended telomere:PCNA [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
Processive synthesis on the C-strand of the telomere (Sus scrofa)
Formation of C-strand Okazaki fragments (Sus scrofa)
Processive complex loaded on telomere [nucleoplasm] (Sus scrofa)
RNA primer-DNA primer:G-strand extended telomere:PCNA [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
Processive complex loaded on telomere:Okazaki fragment complex [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
Formation of the Flap Intermediate on the C-strand (Sus scrofa)
Processive complex loaded on telomere:Okazaki fragment complex [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
Processive complex loaded on telomere:Okazaki fragment:Flap [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
Joining of adjacent Okazaki fragments of the C-strand (Sus scrofa)
Processive complex loaded on telomere:ligated C-strand Okazaki fragments [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
Processive complex loaded on telomere:nicked DNA from adjacent Okazaki fragments [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
Removal of the Flap Intermediate from the C-strand (Sus scrofa)
RPA binds to the Flap on the C-strand (Sus scrofa)
Processive complex loaded on telomere:Okazaki fragment:Flap [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
Processive complex loaded on telomere:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Sus scrofa)
Processive complex loaded on telomere:Okazaki fragment:Flap [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
Recruitment of DNA2 endonuclease to the C strand (Sus scrofa)
Processive complex loaded on telomere:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Sus scrofa)
Processive complex loaded on telomere:Okazaki fragment:Flap [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
Processive complex loaded on telomere:Okazaki fragment:Flap:RPA heterotrimer:DNA2 [nucleoplasm] (Sus scrofa)
Processive complex loaded on telomere:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Sus scrofa)
Processive complex loaded on telomere:Okazaki fragment:Flap [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
Removal of RNA primer and dissociation of RPA and Dna2 from the C-strand (Sus scrofa)
Processive complex loaded on telomere:Okazaki fragment:Flap:RPA heterotrimer:DNA2 [nucleoplasm] (Sus scrofa)
Processive complex loaded on telomere:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Sus scrofa)
Processive complex loaded on telomere:Okazaki fragment:Flap [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
Processive complex loaded on telomere:Okazaki fragments:Remaining Flap [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
Removal of remaining Flap from the C-strand (Sus scrofa)
Processive complex loaded on telomere:Okazaki fragments:Remaining Flap [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
Processive complex loaded on telomere:nicked DNA from adjacent Okazaki fragments [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
Telomere C-strand synthesis initiation (Sus scrofa)
DNA polymerase:primase binds G-strand of the telomere (Sus scrofa)
POLA:primase:G-strand extended telomere end [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
Telomeric G-strand chromosome end with two additional single strand repeats [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere (Sus scrofa)
RNA primer:DNA primer:G-strand extended telomere:POLA:primase [nucleoplasm] (Sus scrofa)
RNA primer:G-strand extended telomere end:POLA:primase [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
RNA primer:G-strand extended telomere end:POLA:primase [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer on the G strand of the telomere (Sus scrofa)
POLA:primase:G-strand extended telomere end [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
RNA primer:G-strand extended telomere end:POLA:primase [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
Telomere Extension By Telomerase (Sus scrofa)
Alignment Of The RNA Template On The Telomeric Chromosome End (Sus scrofa)
Telomerase RNP Bound and base-paired to the Telomeric Chromosome End [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
Telomerase RNP:G-strand telomeric chromosome end [nucleoplasm] (Sus scrofa)
Telomeric G-strand chromosome end:Shelterin [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
CDK2:CCNA phosphorylates TERF2 (Sus scrofa)
Telomeric G-strand chromosome end:Shelterin [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
Disassociation of Telomerase RNP and the Chromosome End (Sus scrofa)
Telomerase Holoenzyme:Telomeric RNP End with Two Additional Single Stranded Telomere Repeats [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
Telomeric G-strand chromosome end with two additional single strand repeats [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
Elongation Of The Telomeric Chromosome End (Sus scrofa)
Telomerase RNP Bound and base-paired to the Telomeric Chromosome End [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
Telomerase RNP:Telomeric Chromosome End with an Additional single Stranded Telomere repeat [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
Elongation of Extended Telomeric Chromosome End (Sus scrofa)
Telomerase Holoenzyme:Telomeric RNP End with Two Additional Single Stranded Telomere Repeats [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
Telomerase RNP:Telomeric Chromosome End with an Additional single Stranded Telomere repeat [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
PP6-PPP6R3 dephosphorylates TERF2 (Sus scrofa)
Telomeric G-strand chromosome end:Shelterin [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
Recruitment of Telomerase RNP to the Telomeric Chromosome End (Sus scrofa)
Telomerase RNP:G-strand telomeric chromosome end [nucleoplasm] (Sus scrofa)
Telomeric G-strand chromosome end:Shelterin [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
Telomeric G-strand chromosome end:Shelterin [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
Translocation Of Telomerase RNP And Alignment Of RNA Template (TERC) To Extended Single Stranded Telomeric Chromosome-End (Sus scrofa)
Telomerase RNP:Telomeric Chromosome End with an Additional single Stranded Telomere repeat [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
Inhibition of DNA recombination at telomere (Sus scrofa)
ATRX:DAXX binds to subtelomeric chromosomal regions (Sus scrofa)
Extended And Processed Telomere End and Associated DNA Binding and Packaging Protein Complex Folded Into Higher Order Structure [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
Telomere:Shelterin:Nucleosome:ATRX:DAXX [nucleoplasm] (Sus scrofa)
Extended And Processed Telomere End and Associated DNA Binding and Packaging Protein Complex Folded Into Higher Order Structure [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
Cellular responses to stimuli (Sus scrofa)
Cellular responses to stress (Sus scrofa)
Cellular Senescence (Sus scrofa)
DNA Damage/Telomere Stress Induced Senescence (Sus scrofa)
Telomere shortening during replicative exhaustion (Sus scrofa)
Extended And Processed Telomere End and Associated DNA Binding and Packaging Protein Complex Folded Into Higher Order Structure [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
DNA Repair (Sus scrofa)
Base Excision Repair (Sus scrofa)
Base-Excision Repair, AP Site Formation (Sus scrofa)
Depurination (Sus scrofa)
Cleavage of the damaged purine (Sus scrofa)
NEIL3 cleaves 5-guanidinohydantoin (Gh) from damaged telomeric DNA (Sus scrofa)
NEIL3:AP-Telomeric DNA:Shelterin [nucleoplasm] (Sus scrofa)
AP-Telomeric DNA:Shelterin [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
NEIL3:Gh-Telomeric DNA:Shelterin [nucleoplasm] (Sus scrofa)
Gh-Telomeric DNA:Shelterin [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
Recognition and association of DNA glycosylase with site containing an affected purine (Sus scrofa)
NEIL3 recognizes and binds to 5-guanidinohydantoin (Gh) in telomeric DNA (Sus scrofa)
Gh-Telomeric DNA:Shelterin [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
NEIL3:Gh-Telomeric DNA:Shelterin [nucleoplasm] (Sus scrofa)
Gh-Telomeric DNA:Shelterin [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
ACD [nucleoplasm]
(Sus scrofa)
POT1 [nucleoplasm]
(Sus scrofa)
TERF1 homodimer [nucleoplasm]
(Sus scrofa)
TERF2 homodimer [nucleoplasm]
(Sus scrofa)
x 2
TERF2IP [nucleoplasm]
(Sus scrofa)
TINF2 [nucleoplasm]
(Sus scrofa)
Participates
as a component of
AP-Telomeric DNA:Shelterin [nucleoplasm] (Sus scrofa)
Gh-Telomeric DNA:Shelterin [nucleoplasm] (Sus scrofa)
Telomere:Shelterin:Nucleosome (H3F3A) [nucleoplasm] (Sus scrofa)
Telomeric G-strand chromosome end:Shelterin [nucleoplasm] (Sus scrofa)
Telomerase RNP Bound and base-paired to the Telomeric Chromosome End [nucleoplasm] (Sus scrofa)
Telomerase RNP:Telomeric Chromosome End with an Additional single Stranded Telomere repeat [nucleoplasm] (Sus scrofa)
Telomerase Holoenzyme:Telomeric RNP End with Two Additional Single Stranded Telomere Repeats [nucleoplasm] (Sus scrofa)
Telomeric G-strand chromosome end with two additional single strand repeats [nucleoplasm] (Sus scrofa)
POLA:primase:G-strand extended telomere end [nucleoplasm] (Sus scrofa)
RNA primer:G-strand extended telomere end:POLA:primase [nucleoplasm] (Sus scrofa)
RFC Heteropentamer:RNA primer-DNA primer:G-strand extended telomere end [nucleoplasm] (Sus scrofa)
RNA primer-DNA primer:G-strand extended telomere:PCNA [nucleoplasm] (Sus scrofa)
Processive complex loaded on telomere:Okazaki fragment complex [nucleoplasm] (Sus scrofa)
Processive complex loaded on telomere:Okazaki fragment:Flap [nucleoplasm] (Sus scrofa)
Processive complex loaded on telomere:Okazaki fragments:Remaining Flap [nucleoplasm] (Sus scrofa)
Processive complex loaded on telomere:nicked DNA from adjacent Okazaki fragments [nucleoplasm] (Sus scrofa)
Processive complex loaded on telomere:ligated C-strand Okazaki fragments [nucleoplasm] (Sus scrofa)
Extended And Processed Telomere End [nucleoplasm] (Sus scrofa)
Extended And Processed Telomere End and Associated DNA Binding and Packaging Protein Complex Folded Into Higher Order Structure [nucleoplasm] (Sus scrofa)
as an output of
Telomere shortening during replicative exhaustion (Sus scrofa)
Inferred From
Shelterin complex [nucleoplasm]
(Homo sapiens)
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