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ACD [nucleoplasm]
Stable Identifier
R-SSC-174889
Type
Protein [EntityWithAccessionedSequence]
Species
Sus scrofa
Compartment
nucleoplasm
Synonyms
ACD, I3LST0
Locations in the PathwayBrowser
Expand all
Cell Cycle (Sus scrofa)
Chromosome Maintenance (Sus scrofa)
Telomere Maintenance (Sus scrofa)
Extension of Telomeres (Sus scrofa)
Telomere C-strand (Lagging Strand) Synthesis (Sus scrofa)
Disassociation of Processive Complex and Completed Telomere End (Sus scrofa)
Extended And Processed Telomere End [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
ACD [nucleoplasm] (Sus scrofa)
Processive complex loaded on telomere:ligated C-strand Okazaki fragments [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
ACD [nucleoplasm] (Sus scrofa)
Polymerase switching on the C-strand of the telomere (Sus scrofa)
Formation of Processive Complex on the C-strand of the telomere (Sus scrofa)
Processive complex loaded on telomere [nucleoplasm] (Sus scrofa)
RNA primer-DNA primer:G-strand extended telomere:PCNA [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
ACD [nucleoplasm] (Sus scrofa)
RNA primer-DNA primer:G-strand extended telomere:PCNA [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
ACD [nucleoplasm] (Sus scrofa)
Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere (Sus scrofa)
RFC Heteropentamer:RNA primer-DNA primer:G-strand extended telomere end [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
ACD [nucleoplasm] (Sus scrofa)
RFC Heteropentamer:RNA primer-DNA primer:G-strand extended telomere end duplex:PCNA homotrimer [nucleoplasm] (Sus scrofa)
RFC Heteropentamer:RNA primer-DNA primer:G-strand extended telomere end [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
ACD [nucleoplasm] (Sus scrofa)
RFC binding displaces Pol Alpha on the C-strand of the telomere (Sus scrofa)
RFC Heteropentamer:RNA primer-DNA primer:G-strand extended telomere end [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
ACD [nucleoplasm] (Sus scrofa)
RNA primer:DNA primer:G-strand extended telomere:POLA:primase [nucleoplasm] (Sus scrofa)
RNA primer:G-strand extended telomere end:POLA:primase [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
ACD [nucleoplasm] (Sus scrofa)
RFC dissociates after sliding clamp formation on the C-strand of the telomere (Sus scrofa)
RFC Heteropentamer:RNA primer-DNA primer:G-strand extended telomere end duplex:PCNA homotrimer [nucleoplasm] (Sus scrofa)
RFC Heteropentamer:RNA primer-DNA primer:G-strand extended telomere end [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
ACD [nucleoplasm] (Sus scrofa)
RNA primer-DNA primer:G-strand extended telomere:PCNA [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
ACD [nucleoplasm] (Sus scrofa)
Processive synthesis on the C-strand of the telomere (Sus scrofa)
Formation of C-strand Okazaki fragments (Sus scrofa)
Processive complex loaded on telomere [nucleoplasm] (Sus scrofa)
RNA primer-DNA primer:G-strand extended telomere:PCNA [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
ACD [nucleoplasm] (Sus scrofa)
Processive complex loaded on telomere:Okazaki fragment complex [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
ACD [nucleoplasm] (Sus scrofa)
Formation of the Flap Intermediate on the C-strand (Sus scrofa)
Processive complex loaded on telomere:Okazaki fragment complex [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
ACD [nucleoplasm] (Sus scrofa)
Processive complex loaded on telomere:Okazaki fragment:Flap [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
ACD [nucleoplasm] (Sus scrofa)
Joining of adjacent Okazaki fragments of the C-strand (Sus scrofa)
Processive complex loaded on telomere:ligated C-strand Okazaki fragments [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
ACD [nucleoplasm] (Sus scrofa)
Processive complex loaded on telomere:nicked DNA from adjacent Okazaki fragments [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
ACD [nucleoplasm] (Sus scrofa)
Removal of the Flap Intermediate from the C-strand (Sus scrofa)
RPA binds to the Flap on the C-strand (Sus scrofa)
Processive complex loaded on telomere:Okazaki fragment:Flap [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
ACD [nucleoplasm] (Sus scrofa)
Processive complex loaded on telomere:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Sus scrofa)
Processive complex loaded on telomere:Okazaki fragment:Flap [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
ACD [nucleoplasm] (Sus scrofa)
Recruitment of DNA2 endonuclease to the C strand (Sus scrofa)
Processive complex loaded on telomere:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Sus scrofa)
Processive complex loaded on telomere:Okazaki fragment:Flap [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
ACD [nucleoplasm] (Sus scrofa)
Processive complex loaded on telomere:Okazaki fragment:Flap:RPA heterotrimer:DNA2 [nucleoplasm] (Sus scrofa)
Processive complex loaded on telomere:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Sus scrofa)
Processive complex loaded on telomere:Okazaki fragment:Flap [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
ACD [nucleoplasm] (Sus scrofa)
Removal of RNA primer and dissociation of RPA and Dna2 from the C-strand (Sus scrofa)
Processive complex loaded on telomere:Okazaki fragment:Flap:RPA heterotrimer:DNA2 [nucleoplasm] (Sus scrofa)
Processive complex loaded on telomere:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Sus scrofa)
Processive complex loaded on telomere:Okazaki fragment:Flap [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
ACD [nucleoplasm] (Sus scrofa)
Processive complex loaded on telomere:Okazaki fragments:Remaining Flap [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
ACD [nucleoplasm] (Sus scrofa)
Removal of remaining Flap from the C-strand (Sus scrofa)
Processive complex loaded on telomere:Okazaki fragments:Remaining Flap [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
ACD [nucleoplasm] (Sus scrofa)
Processive complex loaded on telomere:nicked DNA from adjacent Okazaki fragments [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
ACD [nucleoplasm] (Sus scrofa)
Telomere C-strand synthesis initiation (Sus scrofa)
DNA polymerase:primase binds G-strand of the telomere (Sus scrofa)
POLA:primase:G-strand extended telomere end [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
ACD [nucleoplasm] (Sus scrofa)
Telomeric G-strand chromosome end with two additional single strand repeats [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
ACD [nucleoplasm] (Sus scrofa)
The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere (Sus scrofa)
RNA primer:DNA primer:G-strand extended telomere:POLA:primase [nucleoplasm] (Sus scrofa)
RNA primer:G-strand extended telomere end:POLA:primase [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
ACD [nucleoplasm] (Sus scrofa)
RNA primer:G-strand extended telomere end:POLA:primase [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
ACD [nucleoplasm] (Sus scrofa)
The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer on the G strand of the telomere (Sus scrofa)
POLA:primase:G-strand extended telomere end [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
ACD [nucleoplasm] (Sus scrofa)
RNA primer:G-strand extended telomere end:POLA:primase [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
ACD [nucleoplasm] (Sus scrofa)
Telomere Extension By Telomerase (Sus scrofa)
Alignment Of The RNA Template On The Telomeric Chromosome End (Sus scrofa)
Telomerase RNP Bound and base-paired to the Telomeric Chromosome End [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
ACD [nucleoplasm] (Sus scrofa)
Telomerase RNP:G-strand telomeric chromosome end [nucleoplasm] (Sus scrofa)
Telomeric G-strand chromosome end:Shelterin [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
ACD [nucleoplasm] (Sus scrofa)
CDK2:CCNA phosphorylates TERF2 (Sus scrofa)
Telomeric G-strand chromosome end:Shelterin (p-S365-TERF2) [nucleoplasm] (Sus scrofa)
Shelterin complex (p-S365-TERF2) [nucleoplasm] (Sus scrofa)
ACD [nucleoplasm] (Sus scrofa)
Telomeric G-strand chromosome end:Shelterin [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
ACD [nucleoplasm] (Sus scrofa)
Disassociation of Telomerase RNP and the Chromosome End (Sus scrofa)
Telomerase Holoenzyme:Telomeric RNP End with Two Additional Single Stranded Telomere Repeats [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
ACD [nucleoplasm] (Sus scrofa)
Telomeric G-strand chromosome end with two additional single strand repeats [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
ACD [nucleoplasm] (Sus scrofa)
Elongation Of The Telomeric Chromosome End (Sus scrofa)
Telomerase RNP Bound and base-paired to the Telomeric Chromosome End [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
ACD [nucleoplasm] (Sus scrofa)
Telomerase RNP:Telomeric Chromosome End with an Additional single Stranded Telomere repeat [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
ACD [nucleoplasm] (Sus scrofa)
Elongation of Extended Telomeric Chromosome End (Sus scrofa)
Telomerase Holoenzyme:Telomeric RNP End with Two Additional Single Stranded Telomere Repeats [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
ACD [nucleoplasm] (Sus scrofa)
Telomerase RNP:Telomeric Chromosome End with an Additional single Stranded Telomere repeat [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
ACD [nucleoplasm] (Sus scrofa)
PP6-PPP6R3 dephosphorylates TERF2 (Sus scrofa)
Telomeric G-strand chromosome end:Shelterin (p-S365-TERF2) [nucleoplasm] (Sus scrofa)
Shelterin complex (p-S365-TERF2) [nucleoplasm] (Sus scrofa)
ACD [nucleoplasm] (Sus scrofa)
Telomeric G-strand chromosome end:Shelterin [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
ACD [nucleoplasm] (Sus scrofa)
Recruitment of Telomerase RNP to the Telomeric Chromosome End (Sus scrofa)
Telomerase RNP:G-strand telomeric chromosome end [nucleoplasm] (Sus scrofa)
Telomeric G-strand chromosome end:Shelterin [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
ACD [nucleoplasm] (Sus scrofa)
Telomeric G-strand chromosome end:Shelterin [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
ACD [nucleoplasm] (Sus scrofa)
Translocation Of Telomerase RNP And Alignment Of RNA Template (TERC) To Extended Single Stranded Telomeric Chromosome-End (Sus scrofa)
Telomerase RNP:Telomeric Chromosome End with an Additional single Stranded Telomere repeat [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
ACD [nucleoplasm] (Sus scrofa)
Inhibition of DNA recombination at telomere (Sus scrofa)
ATRX:DAXX binds to subtelomeric chromosomal regions (Sus scrofa)
Extended And Processed Telomere End and Associated DNA Binding and Packaging Protein Complex Folded Into Higher Order Structure [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
ACD [nucleoplasm] (Sus scrofa)
Telomere:Shelterin:Nucleosome:ATRX:DAXX [nucleoplasm] (Sus scrofa)
Extended And Processed Telomere End and Associated DNA Binding and Packaging Protein Complex Folded Into Higher Order Structure [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
ACD [nucleoplasm] (Sus scrofa)
Histone H3.3 deposition at telomere (Sus scrofa)
Telomere:Shelterin:Nucleosome (H3F3A):ATRX:DAXX [nucleoplasm] (Sus scrofa)
Telomere:Shelterin:Nucleosome (H3F3A) [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
ACD [nucleoplasm] (Sus scrofa)
Telomere:Shelterin:Nucleosome:ATRX:DAXX [nucleoplasm] (Sus scrofa)
Extended And Processed Telomere End and Associated DNA Binding and Packaging Protein Complex Folded Into Higher Order Structure [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
ACD [nucleoplasm] (Sus scrofa)
Packaging Of Telomere Ends (Sus scrofa)
Incorporation Of Extended And Processed Telomere End Into Associated Protein Structure (Sus scrofa)
Extended And Processed Telomere End [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
ACD [nucleoplasm] (Sus scrofa)
Extended And Processed Telomere End and Associated DNA Binding and Packaging Protein Complex [nucleoplasm] (Sus scrofa)
Extended And Processed Telomere End [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
ACD [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
ACD [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
ACD [nucleoplasm] (Sus scrofa)
Incorporation Of Extended And Processed Telomere End Into Higher Order T-Loop And Associated Protein Structure (Sus scrofa)
Extended And Processed Telomere End and Associated DNA Binding and Packaging Protein Complex Folded Into Higher Order Structure [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
ACD [nucleoplasm] (Sus scrofa)
Extended And Processed Telomere End and Associated DNA Binding and Packaging Protein Complex [nucleoplasm] (Sus scrofa)
Extended And Processed Telomere End [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
ACD [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
ACD [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
ACD [nucleoplasm] (Sus scrofa)
Cellular responses to stimuli (Sus scrofa)
Cellular responses to stress (Sus scrofa)
Cellular Senescence (Sus scrofa)
DNA Damage/Telomere Stress Induced Senescence (Sus scrofa)
Telomere shortening during replicative exhaustion (Sus scrofa)
Extended And Processed Telomere End and Associated DNA Binding and Packaging Protein Complex Folded Into Higher Order Structure [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
ACD [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
ACD [nucleoplasm] (Sus scrofa)
DNA Repair (Sus scrofa)
Base Excision Repair (Sus scrofa)
Base-Excision Repair, AP Site Formation (Sus scrofa)
Depurination (Sus scrofa)
Cleavage of the damaged purine (Sus scrofa)
NEIL3 cleaves 5-guanidinohydantoin (Gh) from damaged telomeric DNA (Sus scrofa)
NEIL3:AP-Telomeric DNA:Shelterin [nucleoplasm] (Sus scrofa)
AP-Telomeric DNA:Shelterin [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
ACD [nucleoplasm] (Sus scrofa)
NEIL3:Gh-Telomeric DNA:Shelterin [nucleoplasm] (Sus scrofa)
Gh-Telomeric DNA:Shelterin [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
ACD [nucleoplasm] (Sus scrofa)
Recognition and association of DNA glycosylase with site containing an affected purine (Sus scrofa)
NEIL3 recognizes and binds to 5-guanidinohydantoin (Gh) in telomeric DNA (Sus scrofa)
Gh-Telomeric DNA:Shelterin [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
ACD [nucleoplasm] (Sus scrofa)
NEIL3:Gh-Telomeric DNA:Shelterin [nucleoplasm] (Sus scrofa)
Gh-Telomeric DNA:Shelterin [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
ACD [nucleoplasm] (Sus scrofa)
External Reference Information
External Reference
UniProt:I3LST0
Gene Names
ACD
Reference Genes
BioGPS Gene:100623181 ACD
ENSEMBL:ENSSSCG00000029590.4
KEGG:ssc:100623181 ACD
Monarch:100623181 ACD
NCBI Gene:100623181 ACD
UCSC:I3LST0 ACD
Reference Transcript
RefSeq:XM_021094092.1 ACD
Other Identifiers
100623181
GO:0000723
GO:0000781
GO:0000783
GO:0001501
GO:0001655
GO:0003677
GO:0005634
GO:0005654
GO:0005694
GO:0005697
GO:0006886
GO:0007004
GO:0010521
GO:0016233
GO:0016604
GO:0030326
GO:0031848
GO:0032200
GO:0032202
GO:0032211
GO:0035282
GO:0042162
GO:0044877
GO:0048856
GO:0070182
GO:0070187
GO:0070198
GO:0070200
GO:0070203
Participates
as a component of
Shelterin complex (p-S365-TERF2) [nucleoplasm] (Sus scrofa)
Shelterin complex [nucleoplasm] (Sus scrofa)
Inferred From
ACD [nucleoplasm]
(Homo sapiens)
Cross References
RefSeq
XP_020949751.1
ENSEMBL
ENSSSCG00000029590
,
ENSSSCP00000027173
,
ENSSSCT00000027655
VGNC
85007
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