Reactome | ASH2L [nucleoplasm]

ASH2L [nucleoplasm]

Stable Identifier

R-SSC-1629834

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

nucleoplasm

Synonyms

ASH2L, A0A4X1VQD7

Locations in the PathwayBrowser

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Immune System (Sus scrofa)

- Adaptive Immune System (Sus scrofa)
  - Regulation of T cell activation by CD28 family (Sus scrofa)
    - Co-inhibition by PD-1 (Sus scrofa)
      - Regulation of PD-L1(CD274) expression (Sus scrofa)
        
        Regulation of PD-L1(CD274) transcription (Sus scrofa)
        
        MLL1,MLL3 complex binding to CD274 gene chromatin (Sus scrofa)
        
        CD274 gene chromatin:MLL1,MLL3 complex [nucleoplasm] (Sus scrofa)
        
        MLL1,MLL3 complex [nucleoplasm] (Sus scrofa)
        
        MLL1 complex [nucleoplasm] (Sus scrofa)
        
        WRAD complex [nucleoplasm] (Sus scrofa)
        
        ASH2L [nucleoplasm] (Sus scrofa)
        
        MLL3 complex [nucleoplasm] (Sus scrofa)
        
        WRAD complex [nucleoplasm] (Sus scrofa)
        
        ASH2L [nucleoplasm] (Sus scrofa)
        
        MLL1,MLL3 complex [nucleoplasm] (Sus scrofa)
        
        MLL1 complex [nucleoplasm] (Sus scrofa)
        
        WRAD complex [nucleoplasm] (Sus scrofa)
        
        ASH2L [nucleoplasm] (Sus scrofa)
        
        MLL3 complex [nucleoplasm] (Sus scrofa)
        
        WRAD complex [nucleoplasm] (Sus scrofa)
        
        ASH2L [nucleoplasm] (Sus scrofa)
        
        Trimethylation of CD274 gene chromatin by MLL1/3 complex (Sus scrofa)
        
        CD274 gene chromatin:MLL1,MLL3 complex [nucleoplasm] (Sus scrofa)
        
        MLL1,MLL3 complex [nucleoplasm] (Sus scrofa)
        
        MLL1 complex [nucleoplasm] (Sus scrofa)
        
        WRAD complex [nucleoplasm] (Sus scrofa)
        
        ASH2L [nucleoplasm] (Sus scrofa)
        
        MLL3 complex [nucleoplasm] (Sus scrofa)
        
        WRAD complex [nucleoplasm] (Sus scrofa)
        
        ASH2L [nucleoplasm] (Sus scrofa)
        
        MLL1,MLL3 complex [nucleoplasm] (Sus scrofa)
        
        MLL1 complex [nucleoplasm] (Sus scrofa)
        
        WRAD complex [nucleoplasm] (Sus scrofa)
        
        ASH2L [nucleoplasm] (Sus scrofa)
        
        MLL3 complex [nucleoplasm] (Sus scrofa)
        
        WRAD complex [nucleoplasm] (Sus scrofa)
        
        ASH2L [nucleoplasm] (Sus scrofa)
        
        MLL1,MLL3_complex:CD274 gene H3K4me3 chromatin [nucleoplasm] (Sus scrofa)
        
        MLL1,MLL3 complex [nucleoplasm] (Sus scrofa)
        
        MLL1 complex [nucleoplasm] (Sus scrofa)
        
        WRAD complex [nucleoplasm] (Sus scrofa)
        
        ASH2L [nucleoplasm] (Sus scrofa)
        
        MLL3 complex [nucleoplasm] (Sus scrofa)
        
        WRAD complex [nucleoplasm] (Sus scrofa)
        
        ASH2L [nucleoplasm] (Sus scrofa)

Signal Transduction (Sus scrofa)

- Signaling by WNT (Sus scrofa)
  - TCF dependent signaling in response to WNT (Sus scrofa)
    - Formation of the beta-catenin:TCF transactivating complex (Sus scrofa)
      - MLL2 complex trimethylates H3K4 at the MYC gene (Sus scrofa)
        
        TCF/LEF:CTNNB1:BCL9:PYGO:MLL2:MEN1 complex [nucleoplasm] (Sus scrofa)
        
        MLL2 complex:MEN1 [nucleoplasm] (Sus scrofa)
        
        MLL2 complex [nucleoplasm] (Sus scrofa)
        
        WRAD complex [nucleoplasm] (Sus scrofa)
        
        ASH2L [nucleoplasm] (Sus scrofa)
      - Recruitment of MLL2 methyltransferase complex (Sus scrofa)
        
        MLL2 complex:MEN1 [nucleoplasm] (Sus scrofa)
        
        MLL2 complex [nucleoplasm] (Sus scrofa)
        
        WRAD complex [nucleoplasm] (Sus scrofa)
        
        ASH2L [nucleoplasm] (Sus scrofa)
        
        TCF/LEF:CTNNB1:BCL9:PYGO:MLL2:MEN1 complex [nucleoplasm] (Sus scrofa)
        
        MLL2 complex:MEN1 [nucleoplasm] (Sus scrofa)
        
        MLL2 complex [nucleoplasm] (Sus scrofa)
        
        WRAD complex [nucleoplasm] (Sus scrofa)
        
        ASH2L [nucleoplasm] (Sus scrofa)

External Reference Information

External Reference

UniProt:A0A4X1VQD7

Gene Names

ASH2L

Reference Genes

BioGPS Gene:100627423 ASH2L

ENSEMBL:ENSSSCG00005037320.1

Monarch:100627423 ASH2L

NCBI Gene:100627423 ASH2L

UCSC:A0A4X1VQD7 ASH2L

Reference Transcript

RefSeq:XM_021074652.1 ASH2L

Other Identifiers

100627423

GO:0000976

GO:0003677

GO:0005515

GO:0005634

GO:0006325

GO:0006974

GO:0008013

GO:0008168

GO:0008270

GO:0008284

GO:0010468

GO:0010557

GO:0016740

GO:0032259

GO:0035097

GO:0043627

GO:0044665

GO:0044666

GO:0045815

GO:0046872

GO:0048188

GO:0071339

Ssc.5076.1.A1_at

Ssc.5076.2.S1_at

Participates

as an input of

Formation of the RBBP5:ASH2L heterodimer (Sus scrofa)

as a component of

Inferred From

ASH2L [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

XP_020930311.1

ENSEMBL

ENSSSCG00000021898, ENSSSCT00000023044, ENSSSCP00000019990

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