Reactome | YWHAH [cytosol]

YWHAH [cytosol]

Stable Identifier

R-SSC-1445107

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

cytosol

Synonyms

YWHAH, F2Z4Y1

Locations in the PathwayBrowser

Expand all

Cell Cycle (Sus scrofa)

- Cell Cycle Checkpoints (Sus scrofa)
  - G2/M Checkpoints (Sus scrofa)
    - G2/M DNA damage checkpoint (Sus scrofa)
      - Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex (Sus scrofa)
        
        Association of p-S216-CDC25C with 14-3-3 proteins (Sus scrofa)
        
        14-3-3 dimer [cytosol] (Sus scrofa)
        
        YWHAH dimer [cytosol] (Sus scrofa)
        
        YWHAH [cytosol] (Sus scrofa)
        
        p-S216-CDC25C:14-3-3 protein complex [cytosol] (Sus scrofa)
        
        14-3-3 dimer [cytosol] (Sus scrofa)
        
        YWHAH dimer [cytosol] (Sus scrofa)
        
        YWHAH [cytosol] (Sus scrofa)

Programmed Cell Death (Sus scrofa)

- Apoptosis (Sus scrofa)
  - Intrinsic Pathway for Apoptosis (Sus scrofa)
    - Activation of BH3-only proteins (Sus scrofa)
      - Activation of BAD and translocation to mitochondria (Sus scrofa)
        
        Activation of BAD by calcineurin (Sus scrofa)
        
        14-3-3 dimer [cytosol] (Sus scrofa)
        
        YWHAH dimer [cytosol] (Sus scrofa)
        
        YWHAH [cytosol] (Sus scrofa)
        
        14-3-3 proteins:p-S99-BAD complex [cytosol] (Sus scrofa)
        
        14-3-3 dimer [cytosol] (Sus scrofa)
        
        YWHAH dimer [cytosol] (Sus scrofa)
        
        YWHAH [cytosol] (Sus scrofa)
        
        Sequestration of BAD protein by 14-3-3 (Sus scrofa)
        
        14-3-3 dimer [cytosol] (Sus scrofa)
        
        YWHAH dimer [cytosol] (Sus scrofa)
        
        YWHAH [cytosol] (Sus scrofa)
        
        14-3-3 proteins:p-S99-BAD complex [cytosol] (Sus scrofa)
        
        14-3-3 dimer [cytosol] (Sus scrofa)
        
        YWHAH dimer [cytosol] (Sus scrofa)
        
        YWHAH [cytosol] (Sus scrofa)

Signal Transduction (Sus scrofa)

- Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Sus scrofa)
  - Signaling by Rho GTPases (Sus scrofa)
    - RHO GTPase Effectors (Sus scrofa)
      - RHO GTPases activate PKNs (Sus scrofa)
        
        Association of p-S216-CDC25C with 14-3-3 proteins (Sus scrofa)
        
        14-3-3 dimer [cytosol] (Sus scrofa)
        
        YWHAH dimer [cytosol] (Sus scrofa)
        
        YWHAH [cytosol] (Sus scrofa)
        
        p-S216-CDC25C:14-3-3 protein complex [cytosol] (Sus scrofa)
        
        14-3-3 dimer [cytosol] (Sus scrofa)
        
        YWHAH dimer [cytosol] (Sus scrofa)
        
        YWHAH [cytosol] (Sus scrofa)

External Reference Information

External Reference

UniProt:F2Z4Y1

Gene Names

YWHAH

Reference Genes

ENSEMBL:ENSSSCG00000010035.5

Other Identifiers

100155504

GO:0002028

GO:0003779

GO:0005737

GO:0005886

GO:0006351

GO:0006355

GO:0006629

GO:0006713

GO:0006886

GO:0007165

GO:0008092

GO:0017080

GO:0019899

GO:0019904

GO:0023052

GO:0030154

GO:0035259

GO:0042802

GO:0042921

GO:0044325

GO:0045893

GO:0046982

GO:0048856

GO:0050774

GO:0086010

GO:0098772

GO:0098793

GO:0098978

GO:0099171

GO:0150048

Ssc.6924.1.S1_at

Participates

as a component of

YWHAH dimer [cytosol] (Sus scrofa)

Inferred From

YWHAH [cytosol] (Homo sapiens)

Cross References

OpenTargets

ENSG00000128245

Ensembl

ENSSSCT00000010992, ENSSSCP00000010705, ENSSSCG00000010035

VGNC

95045