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RBX1 [nucleoplasm]
Stable Identifier
R-SSC-1234142
Type
Protein [EntityWithAccessionedSequence]
Species
Sus scrofa
Compartment
nucleoplasm
Synonyms
RBX1, A0A287B501
Locations in the PathwayBrowser
Expand all
Cell Cycle (Sus scrofa)
Cell Cycle, Mitotic (Sus scrofa)
S Phase (Sus scrofa)
Synthesis of DNA (Sus scrofa)
Switching of origins to a post-replicative state (Sus scrofa)
Orc1 removal from chromatin (Sus scrofa)
Phosphorylated Orc1 is ubiquitinated while still associated with chromatin (Sus scrofa)
SCF (SKP2) complex [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
Cellular responses to stimuli (Sus scrofa)
Cellular responses to stress (Sus scrofa)
Cellular response to chemical stress (Sus scrofa)
KEAP1-NFE2L2 pathway (Sus scrofa)
Nuclear events mediated by NFE2L2 (Sus scrofa)
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 (Sus scrofa)
BTRC binds p-S344, 347 NFE2L2 (Sus scrofa)
BTRC:SKP1:CUL1:RBX1:p-S344, S347 NFE2L2 [nucleoplasm] (Sus scrofa)
BTRC:SKP1:RBX1:CUL1 [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
BTRC:SKP1:RBX1:CUL1 [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
NFE2L2 is ubiquitinated by BTRC:SKP1:CUL1:RBX1 (Sus scrofa)
BTRC:SKP1:CUL1:RBX1:p-S344, S347 NFE2L2 [nucleoplasm] (Sus scrofa)
BTRC:SKP1:RBX1:CUL1 [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
BTRC:SKP1:CUL1:RBX1:ub,p-S335, S338 NFE2L2 [nucleoplasm] (Sus scrofa)
BTRC:SKP1:RBX1:CUL1 [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
Ub,pS335,S338,T NFE2L2 is degraded (Sus scrofa)
BTRC:SKP1:CUL1:RBX1:ub,p-S335, S338 NFE2L2 [nucleoplasm] (Sus scrofa)
BTRC:SKP1:RBX1:CUL1 [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
BTRC:SKP1:RBX1:CUL1 [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
Regulation of BACH1 activity (Sus scrofa)
BACH1:FBXL17 binds SCF(SKP2) complex (Sus scrofa)
BACH1:FBXL17:SCF (SKP2) [nucleoplasm] (Sus scrofa)
SCF (SKP2) complex [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
SCF (SKP2) complex [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
FBXL17 ubiquitinates BACH1 (in BACH1:FBXL17:SCF (SKP2)) (Sus scrofa)
BACH1:FBXL17:SCF (SKP2) [nucleoplasm] (Sus scrofa)
SCF (SKP2) complex [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
SCF (SKP2) complex [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
Cellular response to hypoxia (Sus scrofa)
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha (Sus scrofa)
Nuclear VBC complex ubiquitinylates HIF-alpha (Sus scrofa)
hydroxyPro-HIF-alpha:VHL:EloB,C:CUL2:RBX1 [nucleoplasm] (Sus scrofa)
VHL:EloB,C:CUL2:RBX1 [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
ub-HIF-alpha:VHL:EloB,C:CUL2:RBX1 [nucleoplasm] (Sus scrofa)
VHL:EloB,C:CUL2:RBX1 [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
Nuclear VHL:EloB,C:CUL2:RBX1 binds hydroxyprolyl-HIF-alpha (Sus scrofa)
VHL:EloB,C:CUL2:RBX1 [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
hydroxyPro-HIF-alpha:VHL:EloB,C:CUL2:RBX1 [nucleoplasm] (Sus scrofa)
VHL:EloB,C:CUL2:RBX1 [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
ub-hydroxyPro-HIF-alpha:VHL:EloB,C:CUL2:RBX1 translocates from the nucleus to the cytosol (Sus scrofa)
ub-HIF-alpha:VHL:EloB,C:CUL2:RBX1 [nucleoplasm] (Sus scrofa)
VHL:EloB,C:CUL2:RBX1 [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
DNA Repair (Sus scrofa)
DNA Damage Bypass (Sus scrofa)
Recognition of DNA damage by PCNA-containing replication complex (Sus scrofa)
RAD18:UBE2B or RBX1:CUL4:DDB1:DTL monoubiquitinates PCNA (Sus scrofa)
RAD18:UBE2B,RBX1:CUL4:DDB1:DTL [nucleoplasm] (Sus scrofa)
RBX1:CUL4:DDB1:DTL [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
RAD18:UBE2B,RBX1:CUL4:DDB1:DTL:PCNA:POLD,POLE:RPA:RFC:Damaged DNA Template [nucleoplasm] (Sus scrofa)
RAD18:UBE2B,RBX1:CUL4:DDB1:DTL [nucleoplasm] (Sus scrofa)
RBX1:CUL4:DDB1:DTL [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
RAD18:UBE2B or RBX1:CUL4:DDB1:DTL ubiquitin ligase complex binds PCNA:POLD,POLE:RPA:RFC associated with damaged dsDNA (Sus scrofa)
RAD18:UBE2B,RBX1:CUL4:DDB1:DTL [nucleoplasm] (Sus scrofa)
RBX1:CUL4:DDB1:DTL [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
RAD18:UBE2B,RBX1:CUL4:DDB1:DTL:PCNA:POLD,POLE:RPA:RFC:Damaged DNA Template [nucleoplasm] (Sus scrofa)
RAD18:UBE2B,RBX1:CUL4:DDB1:DTL [nucleoplasm] (Sus scrofa)
RBX1:CUL4:DDB1:DTL [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
Nucleotide Excision Repair (Sus scrofa)
Global Genome Nucleotide Excision Repair (GG-NER) (Sus scrofa)
DNA Damage Recognition in GG-NER (Sus scrofa)
PARP1 or PARP2 PARylates DDB2 and autoPARylates (Sus scrofa)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Sus scrofa)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB [nucleoplasm] (Sus scrofa)
PAR-UV-DDB [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:UV-DDB:PARP1,PARP2 [nucleoplasm] (Sus scrofa)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:UV-DDB [nucleoplasm] (Sus scrofa)
UV-DDB [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
PARP1 or PARP2 binds DDB2 at GG-NER site (Sus scrofa)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:UV-DDB [nucleoplasm] (Sus scrofa)
UV-DDB [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:UV-DDB:PARP1,PARP2 [nucleoplasm] (Sus scrofa)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:UV-DDB [nucleoplasm] (Sus scrofa)
UV-DDB [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
UV-DDB ubiquitinates XPC (Sus scrofa)
UV-DDB [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:UV-DDB [nucleoplasm] (Sus scrofa)
UV-DDB [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
XPC:RAD23:CETN2:Distorted dsDNA:UV-DDB [nucleoplasm] (Sus scrofa)
UV-DDB [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
Dual Incision in GG-NER (Sus scrofa)
3'-incision of DNA by ERCC5 (XPG) in GG-NER (Sus scrofa)
GG-NER incision complex:5'-incised damaged DNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Sus scrofa)
PAR-UV-DDB [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
PAR-UV-DDB [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
5'- incision of DNA by ERCC1:ERCC4 in GG-NER (Sus scrofa)
GG-NER incision complex:5'-incised damaged DNA [nucleoplasm] (Sus scrofa)
PAR-UV-DDB [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
GG-NER incision complex:Open bubble dsDNA [nucleoplasm] (Sus scrofa)
GG-NER pre-incision complex:Open bubble-dsDNA [nucleoplasm] (Sus scrofa)
Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1, PAR-PARP2:CHD1L [nucleoplasm] (Sus scrofa)
PAR-UV-DDB [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
DNA polymerases delta, epsilon or kappa bind the GG-NER site (Sus scrofa)
GG-NER incision complex:5'-incised damaged DNA [nucleoplasm] (Sus scrofa)
PAR-UV-DDB [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
GG-NER incision complex:5'-incised damaged DNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Sus scrofa)
PAR-UV-DDB [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
Formation of Incision Complex in GG-NER (Sus scrofa)
Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in GG-NER (Sus scrofa)
GG-NER incision complex:Open bubble dsDNA [nucleoplasm] (Sus scrofa)
GG-NER pre-incision complex:Open bubble-dsDNA [nucleoplasm] (Sus scrofa)
Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1, PAR-PARP2:CHD1L [nucleoplasm] (Sus scrofa)
PAR-UV-DDB [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
GG-NER pre-incision complex:Open bubble-dsDNA [nucleoplasm] (Sus scrofa)
Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1, PAR-PARP2:CHD1L [nucleoplasm] (Sus scrofa)
PAR-UV-DDB [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
CHD1L is recruited to GG-NER site (Sus scrofa)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Sus scrofa)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Sus scrofa)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB [nucleoplasm] (Sus scrofa)
PAR-UV-DDB [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2:CHD1L [nucleoplasm] (Sus scrofa)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Sus scrofa)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Sus scrofa)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB [nucleoplasm] (Sus scrofa)
PAR-UV-DDB [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA (Sus scrofa)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2:CHD1L [nucleoplasm] (Sus scrofa)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Sus scrofa)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Sus scrofa)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB [nucleoplasm] (Sus scrofa)
PAR-UV-DDB [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
Ub:XPC:RAD23:CETN2:Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2:CHD1L [nucleoplasm] (Sus scrofa)
Ub:XPC:RAD23:CETN2:Open bubble-dsDNA:PAR-UV-DDB [nucleoplasm] (Sus scrofa)
PAR-UV-DDB [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
Formation of the pre-incision complex in GG-NER (Sus scrofa)
GG-NER pre-incision complex:Open bubble-dsDNA [nucleoplasm] (Sus scrofa)
Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1, PAR-PARP2:CHD1L [nucleoplasm] (Sus scrofa)
PAR-UV-DDB [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1, PAR-PARP2:CHD1L [nucleoplasm] (Sus scrofa)
PAR-UV-DDB [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
Recruitment of XPA and release of CAK (Sus scrofa)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Sus scrofa)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Sus scrofa)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB [nucleoplasm] (Sus scrofa)
PAR-UV-DDB [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Sus scrofa)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Sus scrofa)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB [nucleoplasm] (Sus scrofa)
PAR-UV-DDB [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
SUMOylation of XPC (Sus scrofa)
Ub,SUMO:XPC:RAD23:CETN2:Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1, PAR-PARP2:CHD1L [nucleoplasm] (Sus scrofa)
PAR-UV-DDB [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
Ub:XPC:RAD23:CETN2:Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2:CHD1L [nucleoplasm] (Sus scrofa)
Ub:XPC:RAD23:CETN2:Open bubble-dsDNA:PAR-UV-DDB [nucleoplasm] (Sus scrofa)
PAR-UV-DDB [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
TFIIH binds GG-NER site to form a verification complex (Sus scrofa)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Sus scrofa)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB [nucleoplasm] (Sus scrofa)
PAR-UV-DDB [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Sus scrofa)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Sus scrofa)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB [nucleoplasm] (Sus scrofa)
PAR-UV-DDB [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
Transcription-Coupled Nucleotide Excision Repair (TC-NER) (Sus scrofa)
Dual incision in TC-NER (Sus scrofa)
3' incision by ERCC5 (XPG) in TC-NER (Sus scrofa)
TC-NER incision complex: 5'-incised damaged DNA:trimmed nascent mRNA:(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Sus scrofa)
ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
TC-NER post-incision complex:incised DNA without lesion:trimmed nascent mRNA:PCNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Sus scrofa)
ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER (Sus scrofa)
TC-NER incision complex [nucleoplasm] (Sus scrofa)
TC-NER pre-incision complex:Open bubble damaged DNA template:RPA:ERCC5:trimmed nascent mRNA [nucleoplasm] (Sus scrofa)
TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Sus scrofa)
Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Sus scrofa)
ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
TC-NER incision complex:5'-incised damaged DNA:trimmed nascent mRNA [nucleoplasm] (Sus scrofa)
ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER (Sus scrofa)
TC-NER incision complex [nucleoplasm] (Sus scrofa)
TC-NER pre-incision complex:Open bubble damaged DNA template:RPA:ERCC5:trimmed nascent mRNA [nucleoplasm] (Sus scrofa)
TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Sus scrofa)
Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Sus scrofa)
ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
TC-NER pre-incision complex:Open bubble damaged DNA template:RPA:ERCC5:trimmed nascent mRNA [nucleoplasm] (Sus scrofa)
TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Sus scrofa)
Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Sus scrofa)
ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
DNA polymerases delta, epsilon or kappa bind the TC-NER site (Sus scrofa)
TC-NER incision complex: 5'-incised damaged DNA:trimmed nascent mRNA:(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Sus scrofa)
ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
TC-NER incision complex:5'-incised damaged DNA:trimmed nascent mRNA [nucleoplasm] (Sus scrofa)
ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
ERCC2-facilitated RNA Pol II backtracking in TC-NER (Sus scrofa)
TC-NER pre-incision complex [nucleoplasm] (Sus scrofa)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Sus scrofa)
ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
TC-NER pre-incision complex:Partially open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Sus scrofa)
Ubiquitinated,hyperphosphorylated RNA Pol II:Partially open bubble damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Sus scrofa)
ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
ERCC3-facilitated RNA Pol II backtracking in TC-NER (Sus scrofa)
TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Sus scrofa)
Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Sus scrofa)
ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
TC-NER pre-incision complex:Partially open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Sus scrofa)
Ubiquitinated,hyperphosphorylated RNA Pol II:Partially open bubble damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Sus scrofa)
ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
ERCC5 and RPA bind TC-NER site (Sus scrofa)
TC-NER pre-incision complex:Open bubble damaged DNA template:RPA:ERCC5:trimmed nascent mRNA [nucleoplasm] (Sus scrofa)
TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Sus scrofa)
Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Sus scrofa)
ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Sus scrofa)
Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Sus scrofa)
ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
Formation of TC-NER Pre-Incision Complex (Sus scrofa)
Assembly of the pre-incision complex in TC-NER (Sus scrofa)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:Ub:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Sus scrofa)
ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:Ub:ERCC6:ERCC8:DDB1:CUL4:RBX1:UVSSA:USP7:XAB2 complex:XPA:TCEA1:HMGN1:EP300 [nucleoplasm] (Sus scrofa)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:Ub:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Sus scrofa)
ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
ERCC8 (CSA) binds stalled RNA Pol II (Sus scrofa)
ERCC8:DDB1:CUL4:RBX1:COP9 Signalosome [nucleoplasm] (Sus scrofa)
ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
Hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Sus scrofa)
ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
ERCC8:DDB1:CUL4:RBX1 ubiquitinates ERCC6 and RNA Pol II (Sus scrofa)
ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
Hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Sus scrofa)
ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:Ub:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Sus scrofa)
ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
UVSSA:USP7 deubiquitinates ERCC6 (Sus scrofa)
TC-NER pre-incision complex [nucleoplasm] (Sus scrofa)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Sus scrofa)
ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:Ub:ERCC6:ERCC8:DDB1:CUL4:RBX1:UVSSA:USP7:XAB2 complex:XPA:TCEA1:HMGN1:EP300 [nucleoplasm] (Sus scrofa)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:Ub:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Sus scrofa)
ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
Gap-filling DNA repair synthesis and ligation in TC-NER (Sus scrofa)
Ligation of newly synthesized repair patch to incised DNA in TC-NER (Sus scrofa)
TC-NER post-incision complex:SSB-dsDNA:trimmed nascent mRNA: (PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Sus scrofa)
ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
TC-NER post-incision complex:dsDNA with transcription bubble [nucleoplasm] (Sus scrofa)
ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER (Sus scrofa)
TC-NER post-incision complex:SSB-dsDNA:trimmed nascent mRNA: (PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Sus scrofa)
ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
TC-NER post-incision complex:incised DNA without lesion:trimmed nascent mRNA:PCNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Sus scrofa)
ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
DNA Replication (Sus scrofa)
Synthesis of DNA (Sus scrofa)
Switching of origins to a post-replicative state (Sus scrofa)
Orc1 removal from chromatin (Sus scrofa)
Phosphorylated Orc1 is ubiquitinated while still associated with chromatin (Sus scrofa)
SCF (SKP2) complex [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
Gene expression (Transcription) (Sus scrofa)
RNA Polymerase II Transcription (Sus scrofa)
Generic Transcription Pathway (Sus scrofa)
Transcriptional regulation by RUNX2 (Sus scrofa)
Regulation of RUNX2 expression and activity (Sus scrofa)
SCF(SKP2) complex binds RUNX2 (Sus scrofa)
RUNX2:SCF(SKP2) [nucleoplasm] (Sus scrofa)
SCF (SKP2) complex [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
SCF (SKP2) complex [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
SCF(SKP2) polyubiquitinates RUNX2 (Sus scrofa)
RUNX2:SCF(SKP2) [nucleoplasm] (Sus scrofa)
SCF (SKP2) complex [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
SCF (SKP2) complex [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
Metabolism of proteins (Sus scrofa)
Post-translational protein modification (Sus scrofa)
Neddylation (Sus scrofa)
AcM-UBE2M transfers NEDD8 to CRL4 E3 ubiquitin ligase complex (Sus scrofa)
NEDD8-AcM-UBE2M:CRL4 E3 ubiquitin ligase:COMMDs:CCDC22:DCUND1,2,4,5 [nucleoplasm] (Sus scrofa)
CRL4 E3 ubiquitin ligase:COMMDs:CCDC22 [nucleoplasm] (Sus scrofa)
RBX1:CUL4:DDB1:DCAFs [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
NEDD8-CRL4 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [nucleoplasm] (Sus scrofa)
NEDD8-CRL4 E3 ligase complex [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
CAND1 binds CRL4 E3 ubiquitin ligase in the nucleus (Sus scrofa)
CRL4 E3 ubiquitin ligase:CAND1 [nucleoplasm] (Sus scrofa)
RBX1:CUL4:DDB1:DCAFs [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
RBX1:CUL4:DDB1:DCAFs [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
COMMDs displace CAND1 from CRL4 E3 ubiquitin ligase complex (Sus scrofa)
CRL4 E3 ubiquitin ligase:CAND1 [nucleoplasm] (Sus scrofa)
RBX1:CUL4:DDB1:DCAFs [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
CRL4 E3 ubiquitin ligase:COMMDs:CCDC22 [nucleoplasm] (Sus scrofa)
RBX1:CUL4:DDB1:DCAFs [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
COP9 signalosome deneddylates nuclear CRL4 E3 ubiquitin ligase complex (Sus scrofa)
CRL4 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [nucleoplasm] (Sus scrofa)
RBX1:CUL4:DDB1:DCAFs [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
NEDD8-CRL4 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [nucleoplasm] (Sus scrofa)
NEDD8-CRL4 E3 ligase complex [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
Signal Transduction (Sus scrofa)
Signaling by Hedgehog (Sus scrofa)
Hedgehog 'on' state (Sus scrofa)
GLI2,3 are degraded by the proteasome (Sus scrofa)
SPOP:CUL3:RBX1 [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
ub-2p-GLI2,3:SPOP:CUL3:RBX1 [nucleoplasm] (Sus scrofa)
SPOP:CUL3:RBX1 [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
SPOP:CUL3:RBX1 ubiquitinates GLI2,3 (Sus scrofa)
2p-GLI:SPOP:CUL3:RBX1 [nucleoplasm] (Sus scrofa)
SPOP:CUL3:RBX1 [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
ub-2p-GLI2,3:SPOP:CUL3:RBX1 [nucleoplasm] (Sus scrofa)
SPOP:CUL3:RBX1 [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
phosphorylated GLI proteins bind SPOP:CUL3:RBX1 (Sus scrofa)
2p-GLI:SPOP:CUL3:RBX1 [nucleoplasm] (Sus scrofa)
SPOP:CUL3:RBX1 [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
SPOP:CUL3:RBX1 [nucleoplasm] (Sus scrofa)
RBX1 [nucleoplasm] (Sus scrofa)
External Reference Information
External Reference
UniProt:A0A287B501
Gene Names
RBX1
Reference Genes
ENSEMBL:ENSSSCG00000034230.3
ENSEMBL:ENSSSCG00005004359.1 RBX1
Other Identifiers
110260638
GO:0000209
GO:0002376
GO:0003824
GO:0004842
GO:0005634
GO:0005654
GO:0005737
GO:0005829
GO:0006511
GO:0006513
GO:0007283
GO:0008270
GO:0016567
GO:0016740
GO:0019005
GO:0022414
GO:0023052
GO:0030163
GO:0031146
GO:0031461
GO:0031462
GO:0031463
GO:0031464
GO:0031465
GO:0031466
GO:0031467
GO:0031625
GO:0032436
GO:0032480
GO:0034450
GO:0036211
GO:0042110
GO:0043123
GO:0043161
GO:0043226
GO:0045116
GO:0045732
GO:0046872
GO:0061629
GO:0061630
GO:0061663
GO:0070936
GO:0071230
GO:0097602
GO:0140096
GO:0140627
GO:1902499
GO:1904263
Ssc.20969.1.A1_at
Participates
as a component of
RBX1:CUL4:DDB1:DCAFs [nucleoplasm] (Sus scrofa)
NEDD8-CRL4 E3 ligase complex [nucleoplasm] (Sus scrofa)
RBX1:CUL4:DDB1:DTL [nucleoplasm] (Sus scrofa)
BTRC:SKP1:RBX1:CUL1 [nucleoplasm] (Sus scrofa)
SPOP:CUL3:RBX1 [nucleoplasm] (Sus scrofa)
SCF (SKP2) complex [nucleoplasm] (Sus scrofa)
ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Sus scrofa)
PAR-UV-DDB [nucleoplasm] (Sus scrofa)
UV-DDB [nucleoplasm] (Sus scrofa)
VHL:EloB,C:CUL2:RBX1 [nucleoplasm] (Sus scrofa)
Other forms of this molecule
RBX1 [cytosol]
Inferred From
RBX1 [nucleoplasm]
(Homo sapiens)
Cross References
OpenTargets
ENSG00000100387
Ensembl
ENSSSCT00000062866
,
ENSSSCG00000034230
,
ENSSSCP00000051365
VGNC
106456
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