Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
Ub [cytosol]
Stable Identifier
R-SSC-113595
Type
Set [DefinedSet]
Species
Sus scrofa
Compartment
cytosol
Synonyms
ubiquitin
Locations in the PathwayBrowser
Expand all
Autophagy (Sus scrofa)
Macroautophagy (Sus scrofa)
Selective autophagy (Sus scrofa)
Aggrephagy (Sus scrofa)
Aggresome dissociates from dynein and microtubule (Sus scrofa)
Poly-vimentin:PolyUb-Misfolded Proteins:HDAC6 [cytosol] (Sus scrofa)
PolyUb-Misfolded Proteins:HDAC6 [cytosol] (Sus scrofa)
PolyUb-Misfolded Proteins [cytosol] (Sus scrofa)
Ub-misfolded nascent CFTR [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Poly-vimentin:PolyUb-Misfolded Proteins:HDAC6:Microtubule:Dynein complex [microtubule organizing center] (Sus scrofa)
PolyUb-Misfolded Proteins:HDAC6:Microtubule:Dynein complex [microtubule organizing center] (Sus scrofa)
PolyUb-Misfolded Proteins:HDAC6:Dynein complex [cytosol] (Sus scrofa)
PolyUb-Misfolded Proteins:HDAC6 [cytosol] (Sus scrofa)
PolyUb-Misfolded Proteins [cytosol] (Sus scrofa)
Ub-misfolded nascent CFTR [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Misfolded proteins bind PRKN:UBE2N:UBE2V1:Ub (Sus scrofa)
Misfolded proteins:PRKN:UBE2N:UBE2V1:Ub [cytosol] (Sus scrofa)
Ub:UBE2N:UBE2V1:PRKN [cytosol] (Sus scrofa)
Ub:UBE2N:UBE2V1 [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ub:UBE2N:UBE2V1:PRKN [cytosol] (Sus scrofa)
Ub:UBE2N:UBE2V1 [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Parkin transfers Ub to misfolded proteins (Sus scrofa)
Misfolded proteins:PRKN:UBE2N:UBE2V1:Ub [cytosol] (Sus scrofa)
Ub:UBE2N:UBE2V1:PRKN [cytosol] (Sus scrofa)
Ub:UBE2N:UBE2V1 [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ub:Misfolded proteins:PRKN:UBE2N:UBE2V1 [cytosol] (Sus scrofa)
Ub-Misfolded Proteins [cytosol] (Sus scrofa)
Ub-misfolded nascent CFTR [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
PolyUb-Misfolded Proteins:HDAC6 bind dynein motor (Sus scrofa)
PolyUb-Misfolded Proteins:HDAC6 [cytosol] (Sus scrofa)
PolyUb-Misfolded Proteins [cytosol] (Sus scrofa)
Ub-misfolded nascent CFTR [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
PolyUb-Misfolded Proteins:HDAC6:Dynein complex [cytosol] (Sus scrofa)
PolyUb-Misfolded Proteins:HDAC6 [cytosol] (Sus scrofa)
PolyUb-Misfolded Proteins [cytosol] (Sus scrofa)
Ub-misfolded nascent CFTR [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
PolyUb-Misfolded proteins bind vimentin to form aggresome (Sus scrofa)
Poly-vimentin:PolyUb-Misfolded Proteins:HDAC6:Microtubule:Dynein complex [microtubule organizing center] (Sus scrofa)
PolyUb-Misfolded Proteins:HDAC6:Microtubule:Dynein complex [microtubule organizing center] (Sus scrofa)
PolyUb-Misfolded Proteins:HDAC6:Dynein complex [cytosol] (Sus scrofa)
PolyUb-Misfolded Proteins:HDAC6 [cytosol] (Sus scrofa)
PolyUb-Misfolded Proteins [cytosol] (Sus scrofa)
Ub-misfolded nascent CFTR [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
PolyUb-Misfolded Proteins:HDAC6:Microtubule:Dynein complex [microtubule organizing center] (Sus scrofa)
PolyUb-Misfolded Proteins:HDAC6:Dynein complex [cytosol] (Sus scrofa)
PolyUb-Misfolded Proteins:HDAC6 [cytosol] (Sus scrofa)
PolyUb-Misfolded Proteins [cytosol] (Sus scrofa)
Ub-misfolded nascent CFTR [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ub:misfolded proteins polymerize to PolyUb:misfolded proteins (Sus scrofa)
PolyUb:Misfolded proteins:PRKN:UBE2N:UBE2V1 [cytosol] (Sus scrofa)
PolyUb-Misfolded Proteins [cytosol] (Sus scrofa)
Ub-misfolded nascent CFTR [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ub:Misfolded proteins:PRKN:UBE2N:UBE2V1 [cytosol] (Sus scrofa)
Ub-Misfolded Proteins [cytosol] (Sus scrofa)
Ub-misfolded nascent CFTR [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Pexophagy (Sus scrofa)
ATM dimer:p-PEX5 ubiquitinates to form ATM dimer:Ub-p-PEX5 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
USP30 deubiquitinates ATM dimer:Ub-p-PEX5 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Cell Cycle (Sus scrofa)
Cell Cycle Checkpoints (Sus scrofa)
G1/S DNA Damage Checkpoints (Sus scrofa)
p53-Dependent G1/S DNA damage checkpoint (Sus scrofa)
p53-Dependent G1 DNA Damage Response (Sus scrofa)
Stabilization of p53 (Sus scrofa)
Autodegradation of the E3 ubiquitin ligase COP1 (Sus scrofa)
Autoubiquitination of phospho-COP1(Ser-387 ) (Sus scrofa)
Ub [cytosol] (Sus scrofa)
ubiquitinated phospho-COP1(ser-387) [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Proteasome mediated degradation of COP1 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
ubiquitinated phospho-COP1(ser-387) [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
p53-Independent G1/S DNA damage checkpoint (Sus scrofa)
p53-Independent DNA Damage Response (Sus scrofa)
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A (Sus scrofa)
Proteolytic degradation of ubiquitinated-Cdc25A (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ub-p-S124-CDC25A [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
G2/M Checkpoints (Sus scrofa)
GTSE1 facilitates proteasome-mediated degradation of TP53 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Cell Cycle, Mitotic (Sus scrofa)
M Phase (Sus scrofa)
Mitotic Metaphase and Anaphase (Sus scrofa)
Mitotic Anaphase (Sus scrofa)
Separation of Sister Chromatids (Sus scrofa)
Degradation of multiubiquitinated Securin (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ubiquitination of Securin by phospho-APC/C:Cdc20 complex (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Mitotic G2-G2/M phases (Sus scrofa)
G2/M Transition (Sus scrofa)
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis (Sus scrofa)
Proteasome degrades AURKA ubiquitinated by SCF-FBXL7 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Proteasome-mediated degradation of PolyUb-FBXL7 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
SCF-FBXL18 ubiquitinates FBXL7 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
SCF-FBXL7 ubiquitinates AURKA (Sus scrofa)
Ub [cytosol] (Sus scrofa)
The role of GTSE1 in G2/M progression after G2 checkpoint (Sus scrofa)
GTSE1 facilitates proteasome-mediated degradation of TP53 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Regulation of mitotic cell cycle (Sus scrofa)
APC/C-mediated degradation of cell cycle proteins (Sus scrofa)
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 (Sus scrofa)
Degradation of multiubiquitinated cell cycle proteins (Sus scrofa)
Ub [cytosol] (Sus scrofa)
multiubiquitinated cell cycle protein:APC/C:Cdh1 complex [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ubiquitination of cell cycle proteins targeted by the APC/C:Cdh1complex (Sus scrofa)
Ub [cytosol] (Sus scrofa)
multiubiquitinated cell cycle protein:APC/C:Cdh1 complex [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins (Sus scrofa)
APC/C:Cdc20 mediated degradation of mitotic proteins (Sus scrofa)
APC/C:Cdc20 mediated degradation of Cyclin B (Sus scrofa)
Degradation of multiubiquitinated Cyclin B (Sus scrofa)
Ub [cytosol] (Sus scrofa)
multiubiquitinated Cyclin B:Cdc2:Cdc20:phospho-APC/C complex [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ubiquitination of Cyclin B by phospho-APC/C:Cdc20 complex (Sus scrofa)
Ub [cytosol] (Sus scrofa)
multiubiquitinated Cyclin B:Cdc2:Cdc20:phospho-APC/C complex [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
APC/C:Cdc20 mediated degradation of Securin (Sus scrofa)
Degradation of multiubiquitinated Securin (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ubiquitination of Securin by phospho-APC/C:Cdc20 complex (Sus scrofa)
Ub [cytosol] (Sus scrofa)
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint (Sus scrofa)
APC-Cdc20 mediated degradation of Nek2A (Sus scrofa)
Degradation of multiubiquitinated Nek2A (Sus scrofa)
Multiubiquitinated Nek2A [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Multiubiquitination of Nek2A (Sus scrofa)
Multiubiquitinated Nek2A [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Cdc20:Phospho-APC/C mediated degradation of Cyclin A (Sus scrofa)
Degradation multiubiquitinated Cyclin A (Sus scrofa)
Ub [cytosol] (Sus scrofa)
multiubiquitinated Cyclin A associated with MCC:APC/C complex [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ubiquitination of Cyclin A by APC/C:Cdc20 complex (Sus scrofa)
Ub [cytosol] (Sus scrofa)
multiubiquitinated Cyclin A associated with MCC:APC/C complex [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Regulation of APC/C activators between G1/S and early anaphase (Sus scrofa)
SCF-beta-TrCP mediated degradation of Emi1 (Sus scrofa)
Ubiquitination of Emi1 by SCF-beta-TrCP (Sus scrofa)
SCF-associated multiubiquitinated Emi1complexes [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
S Phase (Sus scrofa)
Synthesis of DNA (Sus scrofa)
Switching of origins to a post-replicative state (Sus scrofa)
CDK-mediated phosphorylation and removal of Cdc6 (Sus scrofa)
Cytoplasmic phosphorylated Cdc6 is ubiquitinated by the anaphase-promoting complex (Sus scrofa)
Ub [cytosol] (Sus scrofa)
ubiquitinated Cdc6 [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ubiquitinated Cdc6 is degraded by the proteasome (Sus scrofa)
Ub [cytosol] (Sus scrofa)
ubiquitinated Cdc6 [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Orc1 removal from chromatin (Sus scrofa)
Ubiquitinated Orc1 is degraded by the proteasome (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ubiquitin-dependent degradation of Cyclin D (Sus scrofa)
Proteasome mediated degradation of Cyclin D1 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
multi-ubiquitinated phospho-(T286) Cyclin D1 [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Cellular responses to stimuli (Sus scrofa)
Cellular responses to stress (Sus scrofa)
Cellular response to chemical stress (Sus scrofa)
KEAP1-NFE2L2 pathway (Sus scrofa)
26S proteasome degrades Ub-NFE2L2 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
CUL3:RBX1 ubiquitinates KEAP1 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
KEAP1:CUL3:RBX1 ubiquitinates p-S349 SQSTM1 oligomer (Sus scrofa)
Ub [cytosol] (Sus scrofa)
KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
MUL1 ubiquitinates UBXN7 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
TRIM21 ubiquitinates SQSTM1 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
ub UBXN7 is degraded by the 26S proteasome (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Cellular response to hypoxia (Sus scrofa)
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha (Sus scrofa)
Cytosolic VBC complex ubiquitinylates hydroxyprolyl-HIF-alpha (Sus scrofa)
UBE2D1,2,3:Ubiquitin [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
ub-hydroxyPro-HIF-alpha:VHL:EloB:EloC:CUL2:RBX1:LIMD1,AJUBA,WTIF:PHD2,3 [cytosol] (Sus scrofa)
ub-hydroxyPro-HIF-alpha [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Proteasome proteolyzes ub-HIF-alpha (Sus scrofa)
Ub [cytosol] (Sus scrofa)
ub-hydroxyPro-HIF-alpha:VCB (with or without LIMD1) [cytosol] (Sus scrofa)
ub-hydroxyPro-HIF-alpha:VHL:EloB:EloC:CUL2:RBX1 [cytosol] (Sus scrofa)
ub-hydroxyPro-HIF-alpha [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
ub-hydroxyPro-HIF-alpha:VHL:EloB:EloC:CUL2:RBX1:LIMD1,AJUBA,WTIF:PHD2,3 [cytosol] (Sus scrofa)
ub-hydroxyPro-HIF-alpha [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
ub-hydroxyPro-HIF-alpha:VHL:EloB,C:CUL2:RBX1 translocates from the nucleus to the cytosol (Sus scrofa)
ub-hydroxyPro-HIF-alpha:VHL:EloB:EloC:CUL2:RBX1 [cytosol] (Sus scrofa)
ub-hydroxyPro-HIF-alpha [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
DNA Replication (Sus scrofa)
Synthesis of DNA (Sus scrofa)
Switching of origins to a post-replicative state (Sus scrofa)
CDK-mediated phosphorylation and removal of Cdc6 (Sus scrofa)
Cytoplasmic phosphorylated Cdc6 is ubiquitinated by the anaphase-promoting complex (Sus scrofa)
Ub [cytosol] (Sus scrofa)
ubiquitinated Cdc6 [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ubiquitinated Cdc6 is degraded by the proteasome (Sus scrofa)
Ub [cytosol] (Sus scrofa)
ubiquitinated Cdc6 [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Orc1 removal from chromatin (Sus scrofa)
Ubiquitinated Orc1 is degraded by the proteasome (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Gene expression (Transcription) (Sus scrofa)
RNA Polymerase II Transcription (Sus scrofa)
Generic Transcription Pathway (Sus scrofa)
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (Sus scrofa)
Downregulation of SMAD2/3:SMAD4 transcriptional activity (Sus scrofa)
USP9X (FAM) deubiquitinates SMAD4 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Transcriptional regulation by RUNX1 (Sus scrofa)
RUNX1 regulates transcription of genes involved in differentiation of HSCs (Sus scrofa)
26S proteasome degrades TP73 polyubiquitinated by ITCH (Sus scrofa)
Ub [cytosol] (Sus scrofa)
ITCH polyubiquitinates TP73 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Transcriptional regulation by RUNX2 (Sus scrofa)
Regulation of RUNX2 expression and activity (Sus scrofa)
STUB1 polyubiquitinates RUNX2 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Transcriptional regulation by RUNX3 (Sus scrofa)
Regulation of RUNX3 expression and activity (Sus scrofa)
Polyubiquitinated RUNX3 is degraded by the proteasome (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Immune System (Sus scrofa)
Adaptive Immune System (Sus scrofa)
Class I MHC mediated antigen processing & presentation (Sus scrofa)
Antigen processing: Ubiquitination & Proteasome degradation (Sus scrofa)
E1 mediated ubiquitin activation (Sus scrofa)
E1 bound ubiquitin [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Interaction of E3 with substrate and E2-Ub complex (Sus scrofa)
Ag-substrate:E3:E2:Ub [cytosol] (Sus scrofa)
Ubiquitin:E2 conjugating enzymes [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ubiquitin:E2 conjugating enzymes [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Polyubiquitination of substrate (Sus scrofa)
E3:Ub:substrate [cytosol] (Sus scrofa)
Ub:substrate [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ubiquitin:E2 conjugating enzymes [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Proteasomal cleavage of substrate (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Transfer of Ub from E2 to substrate and release of E2 (Sus scrofa)
Ag-substrate:E3:E2:Ub [cytosol] (Sus scrofa)
Ubiquitin:E2 conjugating enzymes [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
E3:Ub:substrate [cytosol] (Sus scrofa)
Ub:substrate [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Transfer of ubiquitin from E1 to E2 (Sus scrofa)
E1 bound ubiquitin [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ubiquitin:E2 conjugating enzymes [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Cytokine Signaling in Immune system (Sus scrofa)
FLT3 Signaling (Sus scrofa)
Negative regulation of FLT3 (Sus scrofa)
Ubiquitination of FLT3 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Interferon Signaling (Sus scrofa)
Interferon alpha/beta signaling (Sus scrofa)
Recruitment of STAT2 to p-IFNAR1 (Sus scrofa)
multiubiquitinated STAT2 [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Signaling by Interleukins (Sus scrofa)
Interleukin-1 family signaling (Sus scrofa)
Interleukin-1 signaling (Sus scrofa)
Beta-TrCP ubiquitinates NFKB p50:p65:phospho IKBA complex (Sus scrofa)
BTRC:CUL1:RBX1:SKP1:NFKB1:RELA:p-S32,S36-NFKBIA:Ub [cytosol] (Sus scrofa)
NFKB1:RELA:p-S32,S36-NFKBIA:Ub [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Sus scrofa)
3xUb,p-S-NFkB p105:TPL2:ABIN2 dissociates due to degradation of p105 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
TAK1-dependent IKK and NF-kappa-B activation (Sus scrofa)
Regulation of NF-kappa B signaling (Sus scrofa)
TRAF2,6 ubiquitinates NLRC5 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
USP14 deubiquitinates NLRC5 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ubiquitination of IKBKG by TRAF6 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ubiquitinated and phosphorylated IKBA binds to and is degraded by the proteasome complex (Sus scrofa)
NFKB1:RELA:p-S32,S36-NFKBIA:Ub [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Interleukin-17 signaling (Sus scrofa)
MAP kinase activation (Sus scrofa)
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Sus scrofa)
3xUb,p-S-NFkB p105:TPL2:ABIN2 dissociates due to degradation of p105 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
TNFR2 non-canonical NF-kB pathway (Sus scrofa)
NIK-->noncanonical NF-kB signaling (Sus scrofa)
26S proteasome processes p-7S-p100:RELB to form p52:RELB (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Innate Immune System (Sus scrofa)
Alpha-protein kinase 1 signaling pathway (Sus scrofa)
Activated TRAF6 synthesizes unanchored polyubiquitin chains upon ALPK1:ADP-heptose stimulation (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Auto ubiquitination of TRAF6 bound to ALPK1:ADP-heptose:TIFA oligomer (Sus scrofa)
Ub [cytosol] (Sus scrofa)
C-type lectin receptors (CLRs) (Sus scrofa)
CLEC7A (Dectin-1) signaling (Sus scrofa)
Dectin-1 mediated noncanonical NF-kB signaling (Sus scrofa)
26S proteasome processes p-7S-p100:RELB to form p52:RELB (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Cytosolic sensors of pathogen-associated DNA (Sus scrofa)
Regulation of innate immune responses to cytosolic DNA (Sus scrofa)
DDX41 ubiquitination by TRIM21 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
DTX4 ubiquitinates p-S172-TBK1 within NLRP4:DTX4:STING:TBK1:IRF3 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
STING ubiquitination by TRIM32 or TRIM56 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
DDX58/IFIH1-mediated induction of interferon-alpha/beta (Sus scrofa)
Negative regulators of DDX58/IFIH1 signaling (Sus scrofa)
CYLD mediated deubiquitination of DDX58 (RIG-I) (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Toll-like Receptor Cascades (Sus scrofa)
Toll Like Receptor 10 (TLR10) Cascade (Sus scrofa)
MyD88 cascade initiated on plasma membrane (Sus scrofa)
IRAK2 mediated activation of TAK1 complex (Sus scrofa)
Activated TRAF6 synthesizes unanchored polyubiquitin chains (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Auto ubiquitination of oligo-TRAF6 bound to p-IRAK2 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
MAP kinase activation (Sus scrofa)
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Sus scrofa)
3xUb,p-S-NFkB p105:TPL2:ABIN2 dissociates due to degradation of p105 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
TAK1-dependent IKK and NF-kappa-B activation (Sus scrofa)
Regulation of NF-kappa B signaling (Sus scrofa)
TRAF2,6 ubiquitinates NLRC5 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
USP14 deubiquitinates NLRC5 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ubiquitination of IKBKG by TRAF6 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Toll Like Receptor 2 (TLR2) Cascade (Sus scrofa)
Toll Like Receptor TLR1:TLR2 Cascade (Sus scrofa)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Sus scrofa)
IRAK2 mediated activation of TAK1 complex (Sus scrofa)
Activated TRAF6 synthesizes unanchored polyubiquitin chains (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Auto ubiquitination of oligo-TRAF6 bound to p-IRAK2 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
MAP kinase activation (Sus scrofa)
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Sus scrofa)
3xUb,p-S-NFkB p105:TPL2:ABIN2 dissociates due to degradation of p105 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
TAK1-dependent IKK and NF-kappa-B activation (Sus scrofa)
Regulation of NF-kappa B signaling (Sus scrofa)
TRAF2,6 ubiquitinates NLRC5 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
USP14 deubiquitinates NLRC5 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ubiquitination of IKBKG by TRAF6 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Toll Like Receptor TLR6:TLR2 Cascade (Sus scrofa)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Sus scrofa)
IRAK2 mediated activation of TAK1 complex (Sus scrofa)
Activated TRAF6 synthesizes unanchored polyubiquitin chains (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Auto ubiquitination of oligo-TRAF6 bound to p-IRAK2 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
MAP kinase activation (Sus scrofa)
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Sus scrofa)
3xUb,p-S-NFkB p105:TPL2:ABIN2 dissociates due to degradation of p105 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
TAK1-dependent IKK and NF-kappa-B activation (Sus scrofa)
Regulation of NF-kappa B signaling (Sus scrofa)
TRAF2,6 ubiquitinates NLRC5 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
USP14 deubiquitinates NLRC5 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ubiquitination of IKBKG by TRAF6 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Toll Like Receptor 3 (TLR3) Cascade (Sus scrofa)
MAP kinase activation (Sus scrofa)
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Sus scrofa)
3xUb,p-S-NFkB p105:TPL2:ABIN2 dissociates due to degradation of p105 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
TAK1-dependent IKK and NF-kappa-B activation (Sus scrofa)
Regulation of NF-kappa B signaling (Sus scrofa)
TRAF2,6 ubiquitinates NLRC5 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
USP14 deubiquitinates NLRC5 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ubiquitination of IKBKG by TRAF6 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Toll Like Receptor 4 (TLR4) Cascade (Sus scrofa)
MyD88-independent TLR4 cascade (Sus scrofa)
TRIF (TICAM1)-mediated TLR4 signaling (Sus scrofa)
Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) (Sus scrofa)
Auto-ubiquitination of TRAF3 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7 (Sus scrofa)
IKKε (IKBKE) is ubiquitinated within the activated TLR4 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
TBK1 is ubiquitinated within TBK1:K63polyUb-TANK:K63polyUb-TRAF3:TRIF:activated TLR4 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
TANK is ubiquitinated within TANK:K63polyUb-TRAF3:TRIF:activated TLR4 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
IKK complex recruitment mediated by RIP1 (Sus scrofa)
K63-linked ubiquitination of RIP1 bound to the activated TLR complex (Sus scrofa)
RIP1 ubiqutin ligases [cytosol] (Sus scrofa)
c-IAP1:UBE2D [cytosol] (Sus scrofa)
UBE2D1,2,3:Ubiquitin [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
c-IAP2:UBE2D [cytosol] (Sus scrofa)
UBE2D1,2,3:Ubiquitin [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
MAP kinase activation (Sus scrofa)
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Sus scrofa)
3xUb,p-S-NFkB p105:TPL2:ABIN2 dissociates due to degradation of p105 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
TAK1-dependent IKK and NF-kappa-B activation (Sus scrofa)
Regulation of NF-kappa B signaling (Sus scrofa)
TRAF2,6 ubiquitinates NLRC5 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
USP14 deubiquitinates NLRC5 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ubiquitination of IKBKG by TRAF6 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
TRAF6-mediated induction of TAK1 complex within TLR4 complex (Sus scrofa)
Activated TRAF6 synthesizes unanchored polyubiquitin chains upon TLR stimulation (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Auto ubiquitination of TRAF6 bound to the activated TLR4 complex (Sus scrofa)
Ub [cytosol] (Sus scrofa)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Sus scrofa)
IRAK2 mediated activation of TAK1 complex (Sus scrofa)
Activated TRAF6 synthesizes unanchored polyubiquitin chains (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Auto ubiquitination of oligo-TRAF6 bound to p-IRAK2 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
MAP kinase activation (Sus scrofa)
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Sus scrofa)
3xUb,p-S-NFkB p105:TPL2:ABIN2 dissociates due to degradation of p105 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
TAK1-dependent IKK and NF-kappa-B activation (Sus scrofa)
Regulation of NF-kappa B signaling (Sus scrofa)
TRAF2,6 ubiquitinates NLRC5 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
USP14 deubiquitinates NLRC5 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ubiquitination of IKBKG by TRAF6 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Toll Like Receptor 5 (TLR5) Cascade (Sus scrofa)
MyD88 cascade initiated on plasma membrane (Sus scrofa)
IRAK2 mediated activation of TAK1 complex (Sus scrofa)
Activated TRAF6 synthesizes unanchored polyubiquitin chains (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Auto ubiquitination of oligo-TRAF6 bound to p-IRAK2 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
MAP kinase activation (Sus scrofa)
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Sus scrofa)
3xUb,p-S-NFkB p105:TPL2:ABIN2 dissociates due to degradation of p105 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
TAK1-dependent IKK and NF-kappa-B activation (Sus scrofa)
Regulation of NF-kappa B signaling (Sus scrofa)
TRAF2,6 ubiquitinates NLRC5 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
USP14 deubiquitinates NLRC5 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ubiquitination of IKBKG by TRAF6 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Toll Like Receptor 7/8 (TLR7/8) Cascade (Sus scrofa)
MyD88 dependent cascade initiated on endosome (Sus scrofa)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Sus scrofa)
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation (Sus scrofa)
Activated TRAF6 synthesizes unanchored polyubiquitin chains upon TLR stimulation (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Auto ubiquitination of oligo-TRAF6 bound to p-IRAK2 at endosome membrane (Sus scrofa)
Ub [cytosol] (Sus scrofa)
MAP kinase activation (Sus scrofa)
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Sus scrofa)
3xUb,p-S-NFkB p105:TPL2:ABIN2 dissociates due to degradation of p105 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
TAK1-dependent IKK and NF-kappa-B activation (Sus scrofa)
Regulation of NF-kappa B signaling (Sus scrofa)
TRAF2,6 ubiquitinates NLRC5 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
USP14 deubiquitinates NLRC5 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ubiquitination of IKBKG by TRAF6 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Toll Like Receptor 9 (TLR9) Cascade (Sus scrofa)
MyD88 dependent cascade initiated on endosome (Sus scrofa)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Sus scrofa)
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation (Sus scrofa)
Activated TRAF6 synthesizes unanchored polyubiquitin chains upon TLR stimulation (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Auto ubiquitination of oligo-TRAF6 bound to p-IRAK2 at endosome membrane (Sus scrofa)
Ub [cytosol] (Sus scrofa)
MAP kinase activation (Sus scrofa)
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Sus scrofa)
3xUb,p-S-NFkB p105:TPL2:ABIN2 dissociates due to degradation of p105 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
TAK1-dependent IKK and NF-kappa-B activation (Sus scrofa)
Regulation of NF-kappa B signaling (Sus scrofa)
TRAF2,6 ubiquitinates NLRC5 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
USP14 deubiquitinates NLRC5 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ubiquitination of IKBKG by TRAF6 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Metabolism (Sus scrofa)
Aerobic respiration and respiratory electron transport (Sus scrofa)
Pyruvate metabolism (Sus scrofa)
Regulation of pyruvate metabolism (Sus scrofa)
CTLH E3 ligase ubiquitinates LDHA (Sus scrofa)
Ub [cytosol] (Sus scrofa)
CTLH E3 ligase ubiquitinates PKM-1 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Metabolism of RNA (Sus scrofa)
Regulation of mRNA stability by proteins that bind AU-rich elements (Sus scrofa)
AUF1 (hnRNP D0) binds and destabilizes mRNA (Sus scrofa)
AUF1 (hnRNP D0) is ubiquitinylated (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Metabolism of proteins (Sus scrofa)
Post-translational protein modification (Sus scrofa)
Asparagine N-linked glycosylation (Sus scrofa)
N-glycan trimming in the ER and Calnexin/Calreticulin cycle (Sus scrofa)
Calnexin/calreticulin cycle (Sus scrofa)
ER Quality Control Compartment (ERQC) (Sus scrofa)
Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol (Sus scrofa)
Ub-unfolded protein:(GlcNAc)2 (Man)9-5 [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ub-unfolded protein:(GlcNAc)2 (Man)9-5 [endoplasmic reticulum quality control compartment] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins (Sus scrofa)
Ub-unfolded protein:(GlcNAc)2 (Man)9-5 [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) (Sus scrofa)
Ub-unfolded protein:(GlcNAc)2 (Man)9-5 [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Deubiquitination (Sus scrofa)
Ovarian tumor domain proteases (Sus scrofa)
OTUD7A hydrolyses K11diUb (Sus scrofa)
Ub [cytosol] (Sus scrofa)
UCH proteinases (Sus scrofa)
UCHL1, UCHL3 cleave ubiquitin adducts (Sus scrofa)
UCHL1,UCHL3:Ub [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ub-specific processing proteases (Sus scrofa)
CYLD mediated deubiquitination of DDX58 (RIG-I) (Sus scrofa)
Ub [cytosol] (Sus scrofa)
USP15 deubiquitinates SMAD1,SMAD2,SMAD3, SMAD7:SMURF,KEAP1 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
USP34 deubiquitinates AXIN1,AXIN2 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
USP5 cleaves polyubiquitin (Sus scrofa)
USP5:Ub [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
USP8 deubiquitinates STAM2:HGS (Sus scrofa)
Ub [cytosol] (Sus scrofa)
USP9X (FAM) deubiquitinates SMAD4 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Neddylation (Sus scrofa)
26S proteasome degrades HIFalpha (Sus scrofa)
Ub [cytosol] (Sus scrofa)
ub-hydroxyPro-HIF-alpha:VHL:EloB:EloC:NEDD8-CUL2:RBX1:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Sus scrofa)
ub-hydroxyPro-HIF-alpha [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
26S proteasome degrades Ub-NFE2L2 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
CUL9:RBX1 ubiquitinates BIRC5 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
MUL1 ubiquitinates UBXN7 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
VHL:EloB,C:NEDD8-CUL2:RBX1 complex ubiquitinylates HIF-alpha (Sus scrofa)
UBE2D1,2,3:Ubiquitin [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
ub-hydroxyPro-HIF-alpha:VHL:EloB:EloC:NEDD8-CUL2:RBX1:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Sus scrofa)
ub-hydroxyPro-HIF-alpha [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
ub UBXN7 is degraded by the 26S proteasome (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Protein ubiquitination (Sus scrofa)
E3 ubiquitin ligases ubiquitinate target proteins (Sus scrofa)
PEX2:PEX10:PEX12 binds PEX5S,L (in PEX5S:PEX13:PEX14) and Ub:UBE2D1,2,3 (Sus scrofa)
PEX2:PEX10:PEX12:PEX5S,L:Ub:UBE2D1,2,3:PEX13:PEX14 [peroxisomal membrane] (Sus scrofa)
Ub:UBE2D1,2,3 [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ub:UBE2D1,2,3 [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
PEX2:PEX10:PEX12 monoubiquitinates PEX5S,L at cysteine-11 (Sus scrofa)
PEX2:PEX10:PEX12:PEX5S,L:Ub:UBE2D1,2,3:PEX13:PEX14 [peroxisomal membrane] (Sus scrofa)
Ub:UBE2D1,2,3 [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
PEX2:PEX10:PEX12:Ub:PEX5S,L:PEX13:PEX14 [peroxisomal membrane] (Sus scrofa)
Ub:PEX5L [peroxisomal membrane] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
RNF144A binds PRKDC and Ubiquitin:UBE2L3 (Sus scrofa)
RNF144A:PRKDC:Ub:UBE2L3 [cytosol] (Sus scrofa)
Ub:UBE2L3 [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ub:UBE2L3 [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
RNF144A polyubiquitinates PRKDC (Sus scrofa)
RNF144A:PRKDC:Ub:UBE2L3 [cytosol] (Sus scrofa)
Ub:UBE2L3 [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ub:UBE2L3 [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
RNF152 binds RRAGA:GDP and Ubiquitin:UBE2D3 (Sus scrofa)
RNF152:RRAGA:GDP:Ub:UBE2N [lysosomal membrane] (Sus scrofa)
Ub:UBE2N [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ub:UBE2N [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
RNF152 polyubiquitinates RRAGA (Sus scrofa)
RNF152:RRAGA:GDP:Ub:UBE2N [lysosomal membrane] (Sus scrofa)
Ub:UBE2N [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ub:UBE2N [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
RNF181 binds BCL10 and Ubiquitin:E2 (Sus scrofa)
RNF181:BCL10:Ub:E2 [cytoplasm] (Sus scrofa)
Ub:UBE2D1,UBE2D2,UBE2D3, UBE2E1,UBE2N [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ub:UBE2D1,UBE2D2,UBE2D3, UBE2E1,UBE2N [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
RNF181 polyubiquinates BCL10 (Sus scrofa)
RNF181:BCL10:Ub:E2 [cytoplasm] (Sus scrofa)
Ub:UBE2D1,UBE2D2,UBE2D3, UBE2E1,UBE2N [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ub:UBE2D1,UBE2D2,UBE2D3, UBE2E1,UBE2N [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Synthesis of active ubiquitin: roles of E1 and E2 enzymes (Sus scrofa)
UBA1 adenylates ubiquitin in the cytosol (Sus scrofa)
Ub [cytosol] (Sus scrofa)
UBA1 conjugates ubiquitin to UBA1 in the cytosol (Sus scrofa)
Ub-Cys632-UBA1 [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
UBA1 conjugates ubiquitin to cytosolic E2 enzymes (Sus scrofa)
Ub-Cys632-UBA1:ubiquitin adenylate [cytosol] (Sus scrofa)
Ub-Cys632-UBA1 [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ub:E2 (UBA1 substrate) [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
UBA6 conjugates ubiquitin to cytosolic E2 enzymes (Sus scrofa)
Ub-Cys625-UBA6:ubiquitin adenylate [cytosol] (Sus scrofa)
Ub-Cys625-UBA6 [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ub:E2 (UBA6 substrate) [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ub-Cys632-UBA1 adenylates ubiquitin in the cytosol (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ub-Cys632-UBA1 [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ub-Cys632-UBA1:ubiquitin adenylate [cytosol] (Sus scrofa)
Ub-Cys632-UBA1 [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Programmed Cell Death (Sus scrofa)
Regulated Necrosis (Sus scrofa)
RIPK1-mediated regulated necrosis (Sus scrofa)
Regulation of necroptotic cell death (Sus scrofa)
ITCH polyubiquitinates MLKL at K50 (Sus scrofa)
p-S-RIPK1:p-S-RIPK3:p-T,S-MLKL:ITCH:Ub:UBE2L3 [cytosol] (Sus scrofa)
Ub:UBE2L3 [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
MLKL binds ITCH (Sus scrofa)
Ub:UBE2L3 [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
p-S-RIPK1:p-S-RIPK3:p-T,S-MLKL:ITCH:Ub:UBE2L3 [cytosol] (Sus scrofa)
Ub:UBE2L3 [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
STUB1 ubiquitinates RIPK3 at K55, K363 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Protein localization (Sus scrofa)
Peroxisomal protein import (Sus scrofa)
PEX1:PEX6:PEX26:ZFAND6 dissociates Ub:PEX5L and PEX7 from PEX14:PEX13:PEX2:PEX10:PEX12 and translocates PEX5L and PEX7 from the peroxisomal membrane to the cytosol (Sus scrofa)
PEX2:PEX10:PEX12:Ub:PEX5L:PEX7:PEX13:PEX14:PEX1:PEX6:PEX26:ZFAND6 [peroxisomal membrane] (Sus scrofa)
PEX2:PEX10:PEX12:Ub:PEX5L:PEX7:PEX13:PEX14 [peroxisomal membrane] (Sus scrofa)
Ub:PEX5L [peroxisomal membrane] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ub:PEX5L [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
PEX2:PEX10:PEX12 binds PEX5L (in PEX5L:PEX7:PEX13:PEX14:PEX2:PEX10:PEX12) and Ub:UBE2D1,2,3 (Sus scrofa)
PEX2:PEX10:PEX12:PEX5L:Ub:UBE2D1,2,3:PEX7:PEX13:PEX14 [peroxisomal membrane] (Sus scrofa)
Ub:UBE2D1,2,3 [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ub:UBE2D1,2,3 [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
PEX2:PEX10:PEX12 binds PEX5S,L (in PEX5S:PEX13:PEX14) and Ub:UBE2D1,2,3 (Sus scrofa)
PEX2:PEX10:PEX12:PEX5S,L:Ub:UBE2D1,2,3:PEX13:PEX14 [peroxisomal membrane] (Sus scrofa)
Ub:UBE2D1,2,3 [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ub:UBE2D1,2,3 [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
PEX2:PEX10:PEX12 monoubiquitinates PEX5L at cysteine-11 (Sus scrofa)
PEX2:PEX10:PEX12:PEX5L:Ub:UBE2D1,2,3:PEX7:PEX13:PEX14 [peroxisomal membrane] (Sus scrofa)
Ub:UBE2D1,2,3 [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
PEX2:PEX10:PEX12:Ub:PEX5L:PEX7:PEX13:PEX14 [peroxisomal membrane] (Sus scrofa)
Ub:PEX5L [peroxisomal membrane] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
PEX2:PEX10:PEX12 monoubiquitinates PEX5S,L at cysteine-11 (Sus scrofa)
PEX2:PEX10:PEX12:PEX5S,L:Ub:UBE2D1,2,3:PEX13:PEX14 [peroxisomal membrane] (Sus scrofa)
Ub:UBE2D1,2,3 [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
PEX2:PEX10:PEX12:Ub:PEX5S,L:PEX13:PEX14 [peroxisomal membrane] (Sus scrofa)
Ub:PEX5L [peroxisomal membrane] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
PEX2:PEX10:PEX12:Ub:PEX5L:PEX7:PEX13:PEX14 binds PEX1:PEX6:PEX26 and ZFAND6 (Sus scrofa)
PEX2:PEX10:PEX12:Ub:PEX5L:PEX7:PEX13:PEX14 [peroxisomal membrane] (Sus scrofa)
Ub:PEX5L [peroxisomal membrane] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
PEX2:PEX10:PEX12:Ub:PEX5L:PEX7:PEX13:PEX14:PEX1:PEX6:PEX26:ZFAND6 [peroxisomal membrane] (Sus scrofa)
PEX2:PEX10:PEX12:Ub:PEX5L:PEX7:PEX13:PEX14 [peroxisomal membrane] (Sus scrofa)
Ub:PEX5L [peroxisomal membrane] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
PEX2:PEX10:PEX12:Ub:PEX5S,L:PEX13:PEX14 binds PEX1:PEX6:PEX26 and ZFAND6 (Sus scrofa)
PEX2:PEX10:PEX12:Ub:PEX5S,L:PEX13:PEX14 [peroxisomal membrane] (Sus scrofa)
Ub:PEX5L [peroxisomal membrane] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
PEX2:PEX10:PEX12:Ub:PEX5S,L:PEX1:PEX6:PEX26:ZFAND6 [peroxisomal membrane] (Sus scrofa)
PEX2:PEX10:PEX12:Ub:PEX5S,L:PEX13:PEX14 [peroxisomal membrane] (Sus scrofa)
Ub:PEX5L [peroxisomal membrane] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
USP9X binds Ub:PEX5L (Sus scrofa)
USP9X:Ub:PEX5L [cytosol] (Sus scrofa)
Ub:PEX5L [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ub:PEX5L [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
USP9X hydrolyzes Ub:PEX5L yielding PEX5L and Ubiquitin (Sus scrofa)
USP9X:Ub:PEX5L [cytosol] (Sus scrofa)
Ub:PEX5L [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Signal Transduction (Sus scrofa)
Death Receptor Signaling (Sus scrofa)
TNF signaling (Sus scrofa)
Regulation of TNFR1 signaling (Sus scrofa)
CYLD hydrolyses K63polyUb on RIPK1 within the TNFR1 complex (Sus scrofa)
Ub [cytosol] (Sus scrofa)
CYLD hydrolyses M1polyUb on RIPK1 within the TNFR1 complex (Sus scrofa)
Ub [cytosol] (Sus scrofa)
K63polyUb-RIPK1 is deubiquitinated (Sus scrofa)
Ub [cytosol] (Sus scrofa)
LUBAC ubiquitinates RIPK1 at K627 (Sus scrofa)
Ub:UBE2L3 [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
MIB2 binds CFLAR (Sus scrofa)
CFLAR:MIB2:Ub:UBE2D1 [cytosol] (Sus scrofa)
Ub:UBE2D1 [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ub:UBE2D1 [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
MIB2 binds CYLD (Sus scrofa)
MIB2:CYLD:UBE2D2 [cytosol] (Sus scrofa)
Ub:UBE2D2 [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ub:UBE2D2 [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
MIB2 binds RIPK1 within TNF-α:TNFR1:TRADD:RIPK1:TRAF2 (Sus scrofa)
TNF-α:TNFR1:TRADD:RIPK1:TRAF2:MIB2:Ub:UBE2D1 [plasma membrane] (Sus scrofa)
Ub:UBE2D1 [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ub:UBE2D1 [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
MIB2 ubiquitinates CFLAR (Sus scrofa)
CFLAR:MIB2:Ub:UBE2D1 [cytosol] (Sus scrofa)
Ub:UBE2D1 [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
MIB2 ubiquitinates CYLD at K338, K530 (Sus scrofa)
MIB2:CYLD:UBE2D2 [cytosol] (Sus scrofa)
Ub:UBE2D2 [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
MIB2 ubiquitinates RIPK1 at K377, K604, K634 (Sus scrofa)
TNF-α:TNFR1:TRADD:RIPK1:TRAF2:MIB2:Ub:UBE2D1 [plasma membrane] (Sus scrofa)
Ub:UBE2D1 [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
RIPK1 binds STUB1 (Sus scrofa)
RIPK1:STUB1:Ub:UBE2D3 [cytosol] (Sus scrofa)
Ub:UBE2D3 [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ub:UBE2D3 [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
SPATA2:CYLD-bound LUBAC ubiquitinates RIPK1 at K627 within the TNFR1 signaling complex (Sus scrofa)
Ub:UBE2L3 [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
STUB1 ubiquitinates RIPK1 at K571, K604, K627 (Sus scrofa)
RIPK1:STUB1:Ub:UBE2D3 [cytosol] (Sus scrofa)
Ub:UBE2D3 [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
p75 NTR receptor-mediated signalling (Sus scrofa)
p75NTR signals via NF-kB (Sus scrofa)
NF-kB is activated and signals survival (Sus scrofa)
IkB is ubiquitinated and degraded (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ubiquitinated phospho-IkB [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
p75NTR recruits signalling complexes (Sus scrofa)
TRAF6 is auto-ubiquitinated (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Intracellular signaling by second messengers (Sus scrofa)
PIP3 activates AKT signaling (Sus scrofa)
PTEN Regulation (Sus scrofa)
Regulation of PTEN localization (Sus scrofa)
PTEN undergoes monoubiquitination (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Regulation of PTEN stability and activity (Sus scrofa)
MKRN1 polyubiquitinates PTEN (Sus scrofa)
Ub [cytosol] (Sus scrofa)
NEDD4, WWP2, CHIP and XIAP polyubiquitinate PTEN (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Proteasome degrades polyubiquitinated PTEN (Sus scrofa)
Ub [cytosol] (Sus scrofa)
RNF146 polyubiquitinates PARylated PTEN (Sus scrofa)
Ub [cytosol] (Sus scrofa)
TRIM27 polyubiquitinates PTEN (Sus scrofa)
Ub [cytosol] (Sus scrofa)
USP13 and OTUD3 deubiquitinate PTEN (Sus scrofa)
Ub [cytosol] (Sus scrofa)
MAPK family signaling cascades (Sus scrofa)
MAPK1/MAPK3 signaling (Sus scrofa)
RAF/MAP kinase cascade (Sus scrofa)
Negative regulation of MAPK pathway (Sus scrofa)
BRAP autoubiquitinates (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Regulation of RAS by GAPs (Sus scrofa)
KBTBD7:CUL3:RBX1 ubiquitinates NF1 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
MAPK6/MAPK4 signaling (Sus scrofa)
MAPK6 is degraded by the 26S proteasome (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Signaling by Hedgehog (Sus scrofa)
Hedgehog 'off' state (Sus scrofa)
Degradation of GLI1 by the proteasome (Sus scrofa)
SCF(beta-TrCP) ubiquitinates p-GLI1 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
GLI3 is processed to GLI3R by the proteasome (Sus scrofa)
SCF(beta-TrCP) ubiquitinates p-GLI3 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Hedgehog 'on' state (Sus scrofa)
NUMB:ITCH ubiquitinates GLI1 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
ub-GLI is degraded by the proteasome (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Hedgehog ligand biogenesis (Sus scrofa)
Hh C-terminal fragments are degraded by the proteasome (Sus scrofa)
Ub [cytosol] (Sus scrofa)
SYVN1 ubiquitinates Hh C-terminal fragments (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Signaling by NOTCH (Sus scrofa)
Signaling by NOTCH1 (Sus scrofa)
Activated NOTCH1 Transmits Signal to the Nucleus (Sus scrofa)
ITCH ubiquitinates DTX (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ub-DTX:ITCH [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Signaling by Non-Receptor Tyrosine Kinases (Sus scrofa)
Signaling by PTK6 (Sus scrofa)
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 (Sus scrofa)
CBL autoubiquitinates (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Signaling by Receptor Tyrosine Kinases (Sus scrofa)
Signaling by EGFR (Sus scrofa)
EGFR downregulation (Sus scrofa)
CBL binds and ubiquitinates phosphorylated Sprouty (Sus scrofa)
EGF-like ligands:p-6Y-EGFR:CBL:Ub-p-Y53/55-SPRY1/2 [plasma membrane] (Sus scrofa)
Ub-p-Y53/55-SPRY1/2 [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
CBL escapes CDC42-mediated inhibition by down-regulating the adaptor molecule Beta-Pix (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ub-Beta-Pix:CDC42:GTP [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
CBL ubiquitinates Sprouty (Sus scrofa)
EGF-like ligands:p-6Y-EGFR:CBL:Ub-p-Y53/55-SPRY1/2 [plasma membrane] (Sus scrofa)
Ub-p-Y53/55-SPRY1/2 [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
CBL-mediated ubiquitination of CIN85 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ubiquitination of stimulated EGFR (CBL) (Sus scrofa)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL [plasma membrane] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ubiquitination of stimulated EGFR (CBL:GRB2) (Sus scrofa)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Signaling by ERBB2 (Sus scrofa)
Downregulation of ERBB2 signaling (Sus scrofa)
CHIP (STUB1) mediates ubiquitination of ERBB2 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ub-ERBB2:ERBIN:Ub-HSP90:CDC37 [plasma membrane] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
CUL5 mediates ubiquitination of ERBB2 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ub-ERBB2:ERBIN:HSP90:CDC37 [plasma membrane] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Downregulation of ERBB2:ERBB3 signaling (Sus scrofa)
Deubiquitination of RNF41 by P-USP8 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ub-RNF41:p-USP8 [cytosol] (Sus scrofa)
Ub-RNF41 [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
RNF41 ubiquitinates ERBB3 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ub-ERBB3 [plasma membrane] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
RNF41 ubiquitinates activated ERBB3 (Sus scrofa)
NRG1/2:Ub-p-10Y-ERBB3:p-ERBB2 [plasma membrane] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Self-ubiquitination of RNF41 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ub-RNF41 [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ubiquitinated RNF41 binds P-USP8 (Sus scrofa)
Ub-RNF41 [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ub-RNF41:p-USP8 [cytosol] (Sus scrofa)
Ub-RNF41 [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Signaling by ERBB4 (Sus scrofa)
Downregulation of ERBB4 signaling (Sus scrofa)
ERBB4 ubiquitination by WWP1/ITCH (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ub-ERBB4:WWP1/ITCH [plasma membrane] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
NEDD4 ubiquitinates ERBB4jmAcyt1s80 dimer (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ub-ERBB4jmAcyt1s80:NEDD4 [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Signaling by FGFR (Sus scrofa)
Signaling by FGFR1 (Sus scrofa)
Negative regulation of FGFR1 signaling (Sus scrofa)
CBL ubiquitinates FRS2 and FGFR1 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ub-Activated FGFR1 complex:Ub-p-FRS2 [plasma membrane] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Spry regulation of FGF signaling (Sus scrofa)
CBL dissociates from ubiquitinated p-SPRY2 (Sus scrofa)
Ub-(Y55/Y227)p-SPRY2 [plasma membrane] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ub:Y55/Y227-pSPRY2:CBL [plasma membrane] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Phosphorylated SPRY2 is ubiquitinated by CBL (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ub:Y55/Y227-pSPRY2:CBL [plasma membrane] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Signaling by FGFR2 (Sus scrofa)
Negative regulation of FGFR2 signaling (Sus scrofa)
CBL ubiquitinates FRS2 and FGFR2 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ub-Activated FGFR2 complex:Ub-p-FRS2 [plasma membrane] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Spry regulation of FGF signaling (Sus scrofa)
CBL dissociates from ubiquitinated p-SPRY2 (Sus scrofa)
Ub-(Y55/Y227)p-SPRY2 [plasma membrane] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ub:Y55/Y227-pSPRY2:CBL [plasma membrane] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Phosphorylated SPRY2 is ubiquitinated by CBL (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ub:Y55/Y227-pSPRY2:CBL [plasma membrane] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Signaling by FGFR3 (Sus scrofa)
Negative regulation of FGFR3 signaling (Sus scrofa)
CBL ubiquitinates FRS2 and FGFR3 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ub-Activated FGFR3 complex:Ub-p-FRS2 [plasma membrane] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Spry regulation of FGF signaling (Sus scrofa)
CBL dissociates from ubiquitinated p-SPRY2 (Sus scrofa)
Ub-(Y55/Y227)p-SPRY2 [plasma membrane] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ub:Y55/Y227-pSPRY2:CBL [plasma membrane] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Phosphorylated SPRY2 is ubiquitinated by CBL (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ub:Y55/Y227-pSPRY2:CBL [plasma membrane] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Signaling by FGFR4 (Sus scrofa)
Negative regulation of FGFR4 signaling (Sus scrofa)
CBL ubiquitinates FRS2 and FGFR4 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ub-Activated FGFR4 complex:Ub-p-FRS2 [plasma membrane] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Spry regulation of FGF signaling (Sus scrofa)
CBL dissociates from ubiquitinated p-SPRY2 (Sus scrofa)
Ub-(Y55/Y227)p-SPRY2 [plasma membrane] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ub:Y55/Y227-pSPRY2:CBL [plasma membrane] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Phosphorylated SPRY2 is ubiquitinated by CBL (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ub:Y55/Y227-pSPRY2:CBL [plasma membrane] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Signaling by MET (Sus scrofa)
Negative regulation of MET activity (Sus scrofa)
CBL monoubiquitinates activated MET (Sus scrofa)
Ub [cytosol] (Sus scrofa)
USP8 deubiquitinates LRIG1 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Signaling by TGFB family members (Sus scrofa)
Signaling by TGF-beta Receptor Complex (Sus scrofa)
TGF-beta receptor signaling activates SMADs (Sus scrofa)
Downregulation of TGF-beta receptor signaling (Sus scrofa)
Degradation of TGF-beta receptor complex (Sus scrofa)
TGFB1:TGFBR2:Ub-p-TGFBR1:Ub-SMAD7 [plasma membrane] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Degradation of ubiquitinated SMAD2 (Sus scrofa)
Ub-SMAD2 [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Degradation of ubiquitinated SMAD3 (Sus scrofa)
Ub-SMAD3 [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
SMURF2 ubiquitinates SMAD2 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ub-SMAD2 [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
STUB1 (CHIP) ubiquitinates SMAD3 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ub-SMAD3 [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) (Sus scrofa)
Disassembly of tight junctions (Sus scrofa)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:Ub-RHOA:SMURF1 [cell junction] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
SMURF1 ubiquitinates RHOA (Sus scrofa)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:Ub-RHOA:SMURF1 [cell junction] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (Sus scrofa)
Downregulation of SMAD2/3:SMAD4 transcriptional activity (Sus scrofa)
USP9X (FAM) deubiquitinates SMAD4 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Signaling by WNT (Sus scrofa)
Beta-catenin independent WNT signaling (Sus scrofa)
PCP/CE pathway (Sus scrofa)
Asymmetric localization of PCP proteins (Sus scrofa)
SMURF1/2 ubiquitinates PRICKLE1 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Degradation of beta-catenin by the destruction complex (Sus scrofa)
Degradation of ubiquitinated beta catenin by the proteasome (Sus scrofa)
Ub [cytosol] (Sus scrofa)
ubiquitinated phospho-beta-catenin:RBX1:SCF(beta-TrCP1) complex [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Multi-ubiquitination of phospho-beta-catenin by RBX1:SCF(beta-TrCP1) (Sus scrofa)
Ub [cytosol] (Sus scrofa)
ubiquitinated phospho-beta-catenin:RBX1:SCF(beta-TrCP1) complex [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
TCF dependent signaling in response to WNT (Sus scrofa)
Degradation of AXIN (Sus scrofa)
AXIN is ubiquitinated by SMURF2 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
RNF146 ubiquitinates ADP-ribosylated AXIN (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ub-RibC-AXIN is degraded by the proteasome (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ubiquitinated AXIN is degraded by the proteasome (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Degradation of DVL (Sus scrofa)
DVL is ubiquitinated by CUL3:KLHL12:RBX1 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
DVL1 is ubiquitinated by HECW1 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ubiquitinated DVL is degraded by the proteasome (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ubiquitinated DVL1 is degraded by the proteasome (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Regulation of FZD by ubiquitination (Sus scrofa)
USP8 deubiquitinates FZD to potentiate WNT signaling (Sus scrofa)
Ub [cytosol] (Sus scrofa)
ZNRF3 autoubiquitinates to promote its internalization (Sus scrofa)
Ub [cytosol] (Sus scrofa)
ZNRF3 ubiquitinates FZD to promote its downregulation (Sus scrofa)
Ub [cytosol] (Sus scrofa)
USP34 deubiquitinates AXIN1,AXIN2 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Transport of small molecules (Sus scrofa)
ABC-family proteins mediated transport (Sus scrofa)
RNF5 and RNF185 ubiquitinate misfolded CFTR (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ub-misfolded nascent CFTR:ERAD complex [endoplasmic reticulum membrane] (Sus scrofa)
Ub-misfolded nascent CFTR [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol (Sus scrofa)
Ub-misfolded nascent CFTR [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ub-misfolded nascent CFTR:ERAD complex [endoplasmic reticulum membrane] (Sus scrofa)
Ub-misfolded nascent CFTR [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
misfolded CFTR is degraded by the 26S proteasome (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Ub-misfolded nascent CFTR [cytosol] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Iron uptake and transport (Sus scrofa)
SKP1:FBXL5:CUL1:NEDD8 ubiquitinylates IREB2 (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Vesicle-mediated transport (Sus scrofa)
Membrane Trafficking (Sus scrofa)
Clathrin-mediated endocytosis (Sus scrofa)
Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle (Sus scrofa)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
EGF:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
EGF:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
BAR domain proteins recruit dynamin (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Sus scrofa)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Sus scrofa)
CLASP proteins:cargo [plasma membrane] (Sus scrofa)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Sus scrofa)
ubiquitinated cargo [plasma membrane] (Sus scrofa)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [plasma membrane] (Sus scrofa)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Sus scrofa)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Sus scrofa)
CLASP proteins:cargo [plasma membrane] (Sus scrofa)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Sus scrofa)
ubiquitinated cargo [plasma membrane] (Sus scrofa)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [plasma membrane] (Sus scrofa)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
CLASP proteins and cargo are recruited to the nascent clathrin-coated pit (Sus scrofa)
CLASP proteins:cargo [plasma membrane] (Sus scrofa)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Sus scrofa)
ubiquitinated cargo [plasma membrane] (Sus scrofa)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [plasma membrane] (Sus scrofa)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Sus scrofa)
CLASP proteins:cargo [plasma membrane] (Sus scrofa)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Sus scrofa)
ubiquitinated cargo [plasma membrane] (Sus scrofa)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [plasma membrane] (Sus scrofa)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Cargo recognition for clathrin-mediated endocytosis (Sus scrofa)
Epsin family proteins bind ubiquitinated cargo (Sus scrofa)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Sus scrofa)
ubiquitinated cargo [plasma membrane] (Sus scrofa)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [plasma membrane] (Sus scrofa)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
ubiquitinated cargo [plasma membrane] (Sus scrofa)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [plasma membrane] (Sus scrofa)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Clathrin recruits PIK3C2A (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Sus scrofa)
CLASP proteins:cargo [plasma membrane] (Sus scrofa)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Sus scrofa)
ubiquitinated cargo [plasma membrane] (Sus scrofa)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [plasma membrane] (Sus scrofa)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Sus scrofa)
CLASP proteins:cargo [plasma membrane] (Sus scrofa)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Sus scrofa)
ubiquitinated cargo [plasma membrane] (Sus scrofa)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [plasma membrane] (Sus scrofa)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Clathrin recruits auxilins to the clathrin-coated vesicle (Sus scrofa)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
EGF:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
EGF:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Sus scrofa)
CLASP proteins:cargo [plasma membrane] (Sus scrofa)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Sus scrofa)
ubiquitinated cargo [plasma membrane] (Sus scrofa)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [plasma membrane] (Sus scrofa)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Dissociation of AAK1 and dephosphorylation of AP-2 mu2 (Sus scrofa)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
EGF:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilinGGC-RAB5:GTP:GAPVD1 [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
PI(4)P:ITSNs:EPS15:REPS1:NECAPs:AP-2:SGIP1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
EGF:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Dynamin-mediated GTP hydrolysis promotes vesicle scission (Sus scrofa)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
EGF:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Sus scrofa)
CLASP proteins:cargo [plasma membrane] (Sus scrofa)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Sus scrofa)
ubiquitinated cargo [plasma membrane] (Sus scrofa)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [plasma membrane] (Sus scrofa)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Endophilins recruit synaptojanins to the clathrin-coated pit (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Sus scrofa)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Sus scrofa)
CLASP proteins:cargo [plasma membrane] (Sus scrofa)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Sus scrofa)
ubiquitinated cargo [plasma membrane] (Sus scrofa)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [plasma membrane] (Sus scrofa)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Sus scrofa)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Sus scrofa)
CLASP proteins:cargo [plasma membrane] (Sus scrofa)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Sus scrofa)
ubiquitinated cargo [plasma membrane] (Sus scrofa)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [plasma membrane] (Sus scrofa)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
F- and N- BAR domain proteins bind the clathrin-coated pit (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Sus scrofa)
CLASP proteins:cargo [plasma membrane] (Sus scrofa)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Sus scrofa)
ubiquitinated cargo [plasma membrane] (Sus scrofa)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [plasma membrane] (Sus scrofa)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Sus scrofa)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Sus scrofa)
CLASP proteins:cargo [plasma membrane] (Sus scrofa)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Sus scrofa)
ubiquitinated cargo [plasma membrane] (Sus scrofa)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [plasma membrane] (Sus scrofa)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
HSPA8-mediated ATP hydrolysis promotes vesicle uncoating (Sus scrofa)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
EGF:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
EGF:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
RAB5 and GAPVD1 bind AP-2 (Sus scrofa)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
EGF:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
SNX9 recruits components of the actin polymerizing machinery (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Sus scrofa)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Sus scrofa)
CLASP proteins:cargo [plasma membrane] (Sus scrofa)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Sus scrofa)
ubiquitinated cargo [plasma membrane] (Sus scrofa)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [plasma membrane] (Sus scrofa)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Sus scrofa)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Sus scrofa)
CLASP proteins:cargo [plasma membrane] (Sus scrofa)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Sus scrofa)
ubiquitinated cargo [plasma membrane] (Sus scrofa)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [plasma membrane] (Sus scrofa)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
SYNJ hydrolyze PI(4,5)P2 to PI(4)P (Sus scrofa)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Sus scrofa)
CLASP proteins:cargo [plasma membrane] (Sus scrofa)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Sus scrofa)
ubiquitinated cargo [plasma membrane] (Sus scrofa)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [plasma membrane] (Sus scrofa)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Sus scrofa)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Sus scrofa)
CLASP proteins:cargo [plasma membrane] (Sus scrofa)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Sus scrofa)
ubiquitinated cargo [plasma membrane] (Sus scrofa)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [plasma membrane] (Sus scrofa)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] (Sus scrofa)
Ub [cytosol] (Sus scrofa)
Participants
members
RPS27A [cytosol]
(Sus scrofa)
UBA52 [cytosol]
(Sus scrofa)
UBC [cytosol]
(Sus scrofa)
Homologues of UBC(1-76) [cytosol]
(Sus scrofa)
Homologues of UBC(77-152) [cytosol]
(Sus scrofa)
Homologues of UBC(153-228) [cytosol]
(Sus scrofa)
Homologues of UBC(229-304) [cytosol]
(Sus scrofa)
Homologues of UBC(305-380) [cytosol]
(Sus scrofa)
Homologues of UBC(381-456) [cytosol]
(Sus scrofa)
Homologues of UBC(457-532) [cytosol]
(Sus scrofa)
Homologues of UBC(533-608) [cytosol]
(Sus scrofa)
Homologues of UBC(609-684) [cytosol]
(Sus scrofa)
Participates
as a component of
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
Ub:PEX5L [cytosol] (Sus scrofa)
USP5:Ub [cytosol] (Sus scrofa)
UCHL1,UCHL3:Ub [cytosol] (Sus scrofa)
Ub:E2 (UBA6 substrate) [cytosol] (Sus scrofa)
Ub-Cys625-UBA6 [cytosol] (Sus scrofa)
Ub:E2 (UBA1 substrate) [cytosol] (Sus scrofa)
Ub-Cys632-UBA1 [cytosol] (Sus scrofa)
Ub:PEX5L [peroxisomal membrane] (Sus scrofa)
Ub:UBE2D1,UBE2D2,UBE2D3, UBE2E1,UBE2N [cytosol] (Sus scrofa)
Ub:UBE2N [cytosol] (Sus scrofa)
Ub:UBE2D1,2,3 [cytosol] (Sus scrofa)
Ub-Activated FGFR1 complex:Ub-p-FRS2 [plasma membrane] (Sus scrofa)
Ub-Activated FGFR4 complex:Ub-p-FRS2 [plasma membrane] (Sus scrofa)
Ub-DTX:ITCH [cytosol] (Sus scrofa)
Ub-unfolded protein:(GlcNAc)2 (Man)9-5 [cytosol] (Sus scrofa)
Ub-unfolded protein:(GlcNAc)2 (Man)9-5 [endoplasmic reticulum quality control compartment] (Sus scrofa)
ub-hydroxyPro-HIF-alpha [cytosol] (Sus scrofa)
Ub-Activated FGFR3 complex:Ub-p-FRS2 [plasma membrane] (Sus scrofa)
Ub:UBE2D1 [cytosol] (Sus scrofa)
Ub:UBE2D2 [cytosol] (Sus scrofa)
ubiquitinated phospho-beta-catenin:RBX1:SCF(beta-TrCP1) complex [cytosol] (Sus scrofa)
Ub-p-S124-CDC25A [cytosol] (Sus scrofa)
ubiquitinated phospho-COP1(ser-387) [cytosol] (Sus scrofa)
Ub-p-Y53/55-SPRY1/2 [cytosol] (Sus scrofa)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] (Sus scrofa)
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL [plasma membrane] (Sus scrofa)
Ub-Beta-Pix:CDC42:GTP [cytosol] (Sus scrofa)
NFKB1:RELA:p-S32,S36-NFKBIA:Ub [cytosol] (Sus scrofa)
ubiquitinated Cdc6 [cytosol] (Sus scrofa)
Ub-p-S252,S497,T501-BORA [cytosol] (Sus scrofa)
multi-ubiquitinated phospho-(T286) Cyclin D1 [cytosol] (Sus scrofa)
K63 linked polyubiquitin chain [cytosol] (Sus scrofa)
Ubiquitinated phospho-IkB [cytosol] (Sus scrofa)
Ub-Activated FGFR2 complex:Ub-p-FRS2 [plasma membrane] (Sus scrofa)
Ub-(Y55/Y227)p-SPRY2 [plasma membrane] (Sus scrofa)
Ub:Y55/Y227-pSPRY2:CBL [plasma membrane] (Sus scrofa)
Ub-ERBB2:ERBIN:HSP90:CDC37 [plasma membrane] (Sus scrofa)
NRG1/2:Ub-p-10Y-ERBB3:p-ERBB2 [plasma membrane] (Sus scrofa)
Ub-ERBB3 [plasma membrane] (Sus scrofa)
Ub-RNF41 [cytosol] (Sus scrofa)
Ub-ERBB2:ERBIN:Ub-HSP90:CDC37 [plasma membrane] (Sus scrofa)
Ub-ERBB4:WWP1/ITCH [plasma membrane] (Sus scrofa)
Ub-ERBB4jmAcyt1s80:NEDD4 [cytosol] (Sus scrofa)
Ub:UBE2L3 [cytosol] (Sus scrofa)
Ub:UBE2D3 [cytosol] (Sus scrofa)
UBE2D1,2,3:Ubiquitin [cytosol] (Sus scrofa)
multiubiquitinated STAT2 [cytosol] (Sus scrofa)
E1 bound ubiquitin [cytosol] (Sus scrofa)
Ubiquitin:E2 conjugating enzymes [cytosol] (Sus scrofa)
Ub:substrate [cytosol] (Sus scrofa)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:Ub-RHOA:SMURF1 [cell junction] (Sus scrofa)
TGFB1:TGFBR2:Ub-p-TGFBR1:Ub-SMAD7 [plasma membrane] (Sus scrofa)
Ub-misfolded nascent CFTR [cytosol] (Sus scrofa)
Ub:UBE2N:UBE2V1 [cytosol] (Sus scrofa)
Ub:Ub-UBE2D2,UBE2D3,UBE2N:UBE2V1,UBE2L3 [cytosol] (Sus scrofa)
SCF-associated multiubiquitinated Emi1complexes [cytosol] (Sus scrofa)
multiubiquitinated Cyclin A associated with MCC:APC/C complex [cytosol] (Sus scrofa)
Multiubiquitinated Nek2A [cytosol] (Sus scrofa)
multiubiquitinated cell cycle protein:APC/C:Cdh1 complex [cytosol] (Sus scrofa)
multiubiquitinated Cyclin B:Cdc2:Cdc20:phospho-APC/C complex [cytosol] (Sus scrofa)
Ub-SMAD3 [cytosol] (Sus scrofa)
Ub-SMAD2 [cytosol] (Sus scrofa)
as an input of
AUF1 (hnRNP D0) is ubiquitinylated (Sus scrofa)
CUL9:RBX1 ubiquitinates BIRC5 (Sus scrofa)
Ub-Cys632-UBA1 adenylates ubiquitin in the cytosol (Sus scrofa)
UBA1 adenylates ubiquitin in the cytosol (Sus scrofa)
SYVN1 ubiquitinates Hh C-terminal fragments (Sus scrofa)
Ubiquitination of FLT3 (Sus scrofa)
TRIM21 ubiquitinates SQSTM1 (Sus scrofa)
MUL1 ubiquitinates UBXN7 (Sus scrofa)
RNF5 and RNF185 ubiquitinate misfolded CFTR (Sus scrofa)
CUL3:RBX1 ubiquitinates KEAP1 (Sus scrofa)
KEAP1:CUL3:RBX1 ubiquitinates p-S349 SQSTM1 oligomer (Sus scrofa)
KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 (Sus scrofa)
CBL ubiquitinates FRS2 and FGFR1 (Sus scrofa)
CBL ubiquitinates FRS2 and FGFR4 (Sus scrofa)
ITCH polyubiquitinates TP73 (Sus scrofa)
NUMB:ITCH ubiquitinates GLI1 (Sus scrofa)
SCF(beta-TrCP) ubiquitinates p-GLI1 (Sus scrofa)
STUB1 polyubiquitinates RUNX2 (Sus scrofa)
SCF(beta-TrCP) ubiquitinates p-GLI3 (Sus scrofa)
ITCH ubiquitinates DTX (Sus scrofa)
DTX4 ubiquitinates p-S172-TBK1 within NLRP4:DTX4:STING:TBK1:IRF3 (Sus scrofa)
DDX41 ubiquitination by TRIM21 (Sus scrofa)
STING ubiquitination by TRIM32 or TRIM56 (Sus scrofa)
CTLH E3 ligase ubiquitinates LDHA (Sus scrofa)
CTLH E3 ligase ubiquitinates PKM-1 (Sus scrofa)
CBL ubiquitinates FRS2 and FGFR3 (Sus scrofa)
Multi-ubiquitination of phospho-beta-catenin by RBX1:SCF(beta-TrCP1) (Sus scrofa)
AXIN is ubiquitinated by SMURF2 (Sus scrofa)
RNF146 ubiquitinates ADP-ribosylated AXIN (Sus scrofa)
SMURF1/2 ubiquitinates PRICKLE1 (Sus scrofa)
DVL is ubiquitinated by CUL3:KLHL12:RBX1 (Sus scrofa)
DVL1 is ubiquitinated by HECW1 (Sus scrofa)
ZNRF3 autoubiquitinates to promote its internalization (Sus scrofa)
ZNRF3 ubiquitinates FZD to promote its downregulation (Sus scrofa)
Autoubiquitination of phospho-COP1(Ser-387 ) (Sus scrofa)
CBL ubiquitinates Sprouty (Sus scrofa)
CBL binds and ubiquitinates phosphorylated Sprouty (Sus scrofa)
Ubiquitination of stimulated EGFR (CBL:GRB2) (Sus scrofa)
CBL-mediated ubiquitination of CIN85 (Sus scrofa)
Ubiquitination of stimulated EGFR (CBL) (Sus scrofa)
CBL escapes CDC42-mediated inhibition by down-regulating the adaptor molecule Beta-Pix (Sus scrofa)
Beta-TrCP ubiquitinates NFKB p50:p65:phospho IKBA complex (Sus scrofa)
Cytoplasmic phosphorylated Cdc6 is ubiquitinated by the anaphase-promoting complex (Sus scrofa)
SCF-FBXL7 ubiquitinates AURKA (Sus scrofa)
SCF-FBXL18 ubiquitinates FBXL7 (Sus scrofa)
CBL autoubiquitinates (Sus scrofa)
IkB is ubiquitinated and degraded (Sus scrofa)
TRAF6 is auto-ubiquitinated (Sus scrofa)
CBL ubiquitinates FRS2 and FGFR2 (Sus scrofa)
Phosphorylated SPRY2 is ubiquitinated by CBL (Sus scrofa)
CUL5 mediates ubiquitination of ERBB2 (Sus scrofa)
RNF41 ubiquitinates ERBB3 (Sus scrofa)
RNF41 ubiquitinates activated ERBB3 (Sus scrofa)
Self-ubiquitination of RNF41 (Sus scrofa)
CHIP (STUB1) mediates ubiquitination of ERBB2 (Sus scrofa)
SKP1:FBXL5:CUL1:NEDD8 ubiquitinylates IREB2 (Sus scrofa)
ERBB4 ubiquitination by WWP1/ITCH (Sus scrofa)
NEDD4 ubiquitinates ERBB4jmAcyt1s80 dimer (Sus scrofa)
CBL monoubiquitinates activated MET (Sus scrofa)
BRAP autoubiquitinates (Sus scrofa)
KBTBD7:CUL3:RBX1 ubiquitinates NF1 (Sus scrofa)
MKRN1 polyubiquitinates PTEN (Sus scrofa)
RNF146 polyubiquitinates PARylated PTEN (Sus scrofa)
TRIM27 polyubiquitinates PTEN (Sus scrofa)
NEDD4, WWP2, CHIP and XIAP polyubiquitinate PTEN (Sus scrofa)
PTEN undergoes monoubiquitination (Sus scrofa)
STUB1 ubiquitinates RIPK3 at K55, K363 (Sus scrofa)
IKKε (IKBKE) is ubiquitinated within the activated TLR4 (Sus scrofa)
TBK1 is ubiquitinated within TBK1:K63polyUb-TANK:K63polyUb-TRAF3:TRIF:activated TLR4 (Sus scrofa)
Auto-ubiquitination of TRAF3 (Sus scrofa)
TANK is ubiquitinated within TANK:K63polyUb-TRAF3:TRIF:activated TLR4 (Sus scrofa)
Activated TRAF6 synthesizes unanchored polyubiquitin chains upon TLR stimulation (Sus scrofa)
Auto ubiquitination of oligo-TRAF6 bound to p-IRAK2 at endosome membrane (Sus scrofa)
Ubiquitination of IKBKG by TRAF6 (Sus scrofa)
E1 mediated ubiquitin activation (Sus scrofa)
SMURF1 ubiquitinates RHOA (Sus scrofa)
SMURF2 ubiquitinates SMAD2 (Sus scrofa)
ATM dimer:p-PEX5 ubiquitinates to form ATM dimer:Ub-p-PEX5 (Sus scrofa)
Ubiquitination of Emi1 by SCF-beta-TrCP (Sus scrofa)
Multiubiquitination of Nek2A (Sus scrofa)
Ubiquitination of Cyclin A by APC/C:Cdc20 complex (Sus scrofa)
Ubiquitination of Cyclin B by phospho-APC/C:Cdc20 complex (Sus scrofa)
Ubiquitination of Securin by phospho-APC/C:Cdc20 complex (Sus scrofa)
Auto ubiquitination of oligo-TRAF6 bound to p-IRAK2 (Sus scrofa)
Activated TRAF6 synthesizes unanchored polyubiquitin chains (Sus scrofa)
Auto ubiquitination of TRAF6 bound to ALPK1:ADP-heptose:TIFA oligomer (Sus scrofa)
Activated TRAF6 synthesizes unanchored polyubiquitin chains upon ALPK1:ADP-heptose stimulation (Sus scrofa)
TRAF2,6 ubiquitinates NLRC5 (Sus scrofa)
Auto ubiquitination of TRAF6 bound to the activated TLR4 complex (Sus scrofa)
Ubiquitination of cell cycle proteins targeted by the APC/C:Cdh1complex (Sus scrofa)
STUB1 (CHIP) ubiquitinates SMAD3 (Sus scrofa)
as an output of
MAPK6 is degraded by the 26S proteasome (Sus scrofa)
USP9X hydrolyzes Ub:PEX5L yielding PEX5L and Ubiquitin (Sus scrofa)
OTUD7A hydrolyses K11diUb (Sus scrofa)
USP5 cleaves polyubiquitin (Sus scrofa)
USP15 deubiquitinates SMAD1,SMAD2,SMAD3, SMAD7:SMURF,KEAP1 (Sus scrofa)
USP8 deubiquitinates STAM2:HGS (Sus scrofa)
26S proteasome degrades HIFalpha (Sus scrofa)
Hh C-terminal fragments are degraded by the proteasome (Sus scrofa)
ub UBXN7 is degraded by the 26S proteasome (Sus scrofa)
misfolded CFTR is degraded by the 26S proteasome (Sus scrofa)
26S proteasome degrades Ub-NFE2L2 (Sus scrofa)
26S proteasome degrades TP73 polyubiquitinated by ITCH (Sus scrofa)
ub-GLI is degraded by the proteasome (Sus scrofa)
Polyubiquitinated RUNX3 is degraded by the proteasome (Sus scrofa)
26S proteasome processes p-7S-p100:RELB to form p52:RELB (Sus scrofa)
Proteasome proteolyzes ub-HIF-alpha (Sus scrofa)
CYLD hydrolyses K63polyUb on RIPK1 within the TNFR1 complex (Sus scrofa)
CYLD hydrolyses M1polyUb on RIPK1 within the TNFR1 complex (Sus scrofa)
K63polyUb-RIPK1 is deubiquitinated (Sus scrofa)
Degradation of ubiquitinated beta catenin by the proteasome (Sus scrofa)
USP34 deubiquitinates AXIN1,AXIN2 (Sus scrofa)
Ubiquitinated AXIN is degraded by the proteasome (Sus scrofa)
Ub-RibC-AXIN is degraded by the proteasome (Sus scrofa)
Ubiquitinated DVL is degraded by the proteasome (Sus scrofa)
Ubiquitinated DVL1 is degraded by the proteasome (Sus scrofa)
USP8 deubiquitinates FZD to potentiate WNT signaling (Sus scrofa)
Proteolytic degradation of ubiquitinated-Cdc25A (Sus scrofa)
Proteasome mediated degradation of COP1 (Sus scrofa)
Ubiquitinated and phosphorylated IKBA binds to and is degraded by the proteasome complex (Sus scrofa)
Ubiquitinated Cdc6 is degraded by the proteasome (Sus scrofa)
Proteasome degrades AURKA ubiquitinated by SCF-FBXL7 (Sus scrofa)
Proteasome-mediated degradation of PolyUb-FBXL7 (Sus scrofa)
Ubiquitinated Orc1 is degraded by the proteasome (Sus scrofa)
Proteasome mediated degradation of Cyclin D1 (Sus scrofa)
Deubiquitination of RNF41 by P-USP8 (Sus scrofa)
USP8 deubiquitinates LRIG1 (Sus scrofa)
Proteasome degrades polyubiquitinated PTEN (Sus scrofa)
USP13 and OTUD3 deubiquitinate PTEN (Sus scrofa)
CYLD mediated deubiquitination of DDX58 (RIG-I) (Sus scrofa)
Proteasomal cleavage of substrate (Sus scrofa)
USP30 deubiquitinates ATM dimer:Ub-p-PEX5 (Sus scrofa)
Degradation multiubiquitinated Cyclin A (Sus scrofa)
Degradation of multiubiquitinated Cyclin B (Sus scrofa)
Degradation of multiubiquitinated Securin (Sus scrofa)
USP14 deubiquitinates NLRC5 (Sus scrofa)
3xUb,p-S-NFkB p105:TPL2:ABIN2 dissociates due to degradation of p105 (Sus scrofa)
USP9X (FAM) deubiquitinates SMAD4 (Sus scrofa)
Degradation of multiubiquitinated cell cycle proteins (Sus scrofa)
Degradation of multiubiquitinated Nek2A (Sus scrofa)
GTSE1 facilitates proteasome-mediated degradation of TP53 (Sus scrofa)
Inferred From
Ub [cytosol]
(Homo sapiens)
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text
