Reactome | Ub-misfolded nascent CFTR [cytosol]

Ub-misfolded nascent CFTR [cytosol]

Stable Identifier

R-SSC-8866534

Type

Complex

Species

Sus scrofa

Compartment

cytosol

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General

This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Participants

components

CFTR [endoplasmic reticulum membrane] (Sus scrofa)
Ub [cytosol] (Sus scrofa)

Participates

as an input of

misfolded CFTR is degraded by the 26S proteasome (Sus scrofa)

as an output of

VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol (Sus scrofa)

as a component of

Ub-misfolded nascent CFTR:ERAD complex [endoplasmic reticulum membrane] (Sus scrofa)

as a member of

Ub-Misfolded Proteins [cytosol] (Sus scrofa)
PolyUb-Misfolded Proteins [cytosol] (Sus scrofa)

Inferred From

Ub-misfolded nascent CFTR [cytosol] (Homo sapiens)

PolyUb-misfolded nascent CFTR [cytosol] (Homo sapiens)