Reactome | Homologues of RPL13A [cytosol]

Homologues of RPL13A [cytosol]

Stable Identifier

R-SPO-72412-3

Type

Set [DefinedSet]

Species

Schizosaccharomyces pombe

Compartment

cytosol

Locations in the PathwayBrowser

Expand all

Metabolism of RNA (Schizosaccharomyces pombe)

- Nonsense-Mediated Decay (NMD) (Schizosaccharomyces pombe)
  - Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Schizosaccharomyces pombe)
    - SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Schizosaccharomyces pombe)
      - SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Schizosaccharomyces pombe)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Schizosaccharomyces pombe)
        
        80S ribosome [cytosol] (Schizosaccharomyces pombe)
        
        60S ribosomal complex [cytosol] (Schizosaccharomyces pombe)
        
        Homologues of RPL13A [cytosol] (Schizosaccharomyces pombe)
      - SMG1:UPF1:EJC:Translated mRNP [cytosol] (Schizosaccharomyces pombe)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Schizosaccharomyces pombe)
        
        80S ribosome [cytosol] (Schizosaccharomyces pombe)
        
        60S ribosomal complex [cytosol] (Schizosaccharomyces pombe)
        
        Homologues of RPL13A [cytosol] (Schizosaccharomyces pombe)
    - SMG6 hydrolyzes mRNA with premature termination codon (Schizosaccharomyces pombe)
      - Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Schizosaccharomyces pombe)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Schizosaccharomyces pombe)
        
        80S ribosome [cytosol] (Schizosaccharomyces pombe)
        
        60S ribosomal complex [cytosol] (Schizosaccharomyces pombe)
        
        Homologues of RPL13A [cytosol] (Schizosaccharomyces pombe)
  - Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) (Schizosaccharomyces pombe)
    - Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex (Schizosaccharomyces pombe)
      - Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Schizosaccharomyces pombe)
        
        80S ribosome [cytosol] (Schizosaccharomyces pombe)
        
        60S ribosomal complex [cytosol] (Schizosaccharomyces pombe)
        
        Homologues of RPL13A [cytosol] (Schizosaccharomyces pombe)
      - UPF1:eRF3 Complex on Translated mRNA [cytosol] (Schizosaccharomyces pombe)
        
        Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Schizosaccharomyces pombe)
        
        80S ribosome [cytosol] (Schizosaccharomyces pombe)
        
        60S ribosomal complex [cytosol] (Schizosaccharomyces pombe)
        
        Homologues of RPL13A [cytosol] (Schizosaccharomyces pombe)

Participants

members

Participates

as an output of

Dissociation of L13a from the 60s ribosomal subunit (Schizosaccharomyces pombe)

as a component of

60S ribosomal complex [cytosol] (Schizosaccharomyces pombe)

Inferred From

RPL13A [cytosol] (Homo sapiens)