Reactome | SKIV2L2 [nucleoplasm]

SKIV2L2 [nucleoplasm]

Stable Identifier

R-SCE-6791189

Type

Protein [EntityWithAccessionedSequence]

Species

Saccharomyces cerevisiae

Compartment

nucleoplasm

Synonyms

P47047

Locations in the PathwayBrowser for interactor UniProt:P25635 PWP2

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External Reference Information

External Reference

UniProt:P47047

Reference Genes

BioGPS Gene:853397

ENSEMBL:YJL050W

KEGG:sce:YJL050W

Monarch:853397

NCBI Gene:853397

SGD:YJL050W

UCSC:P47047

Reference Transcript

RefSeq:NM_001181483.1

Other Identifiers

853397

GO:0000166

GO:0000292

GO:0000460

GO:0000467

GO:0003674

GO:0003676

GO:0003723

GO:0003724

GO:0003729

GO:0003824

GO:0004386

GO:0005515

GO:0005524

GO:0005575

GO:0005634

GO:0005730

GO:0006364

GO:0006397

GO:0006401

GO:0008143

GO:0008150

GO:0016075

GO:0016491

GO:0016787

GO:0016887

GO:0031499

GO:0034458

GO:0034475

GO:0034476

GO:0043144

GO:0043167

GO:0043629

GO:0071028

GO:0071031

GO:0071035

GO:0071038

GO:0071042

GO:0071049

GO:0071051

GO:0140657

Participates

as a component of

This entity regulates

Positively

21S pre-rRNA is nucleolytically processed at site E (site2a) to yield 18SE pre-rRNA (Saccharomyces cerevisiae)

Inferred From

SKIV2L2 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_012485.1

ENSEMBL

YJL050W, YJL050W_mRNA, YJL050W

IntEnz

3.6.4.13

PRO

P47047

PDB

7AJT, 6FT6, 4WFD, 7AJU, 6FSZ, 5OOQ, 7D4I, 2XGJ, 4U4C, 4QU4, 6LQS

Interactors (36)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P53632 PAP2			0.941	29
UniProt:Q12476 AIR2			0.922	27
UniProt:P48561 TRF5			0.884	13
UniProt:P40507 AIR1			0.771	10
UniProt:Q12149	1	EXOSC10 [nucleoplasm] (R-SCE-6791547)	0.688	4
UniProt:Q12080 NOP53			0.669	8
UniProt:Q08965 BMS1	2	BMS1 [nucleoplasm] (R-SCE-6790720) BMS1 [nucleoplasm] (R-SCE-6790636)	0.648	4
UniProt:Q12159 YRA1			0.564	18
UniProt:P04147	1	PAB1 [cytosol] (R-SCE-156803)	0.564	2
UniProt:P50095	5	IMPDH1 [secretory granule lumen] (R-SCE-6800971-3) IMPDH1 [ficolin-1-rich granule lumen] (R-SCE-6800927-3) IMPDH1 [extracellular region] (R-SCE-6806182-3) IMPDH1 [azurophil granule lumen] (R-SCE-6799173-3) IMPDH1 [cytosol] (R-SCE-57348-3)	0.564	2
UniProt:P25359 RRP43	2	RRP43 [nucleoplasm] (R-SCE-6791571) RRP43 [cytosol] (R-SCE-429912)	0.564	6
UniProt:Q12754 RRP12			0.527	3
UniProt:Q08162 DIS3	2	DIS3 [nucleoplasm] (R-SCE-6791517) DIS3 [cytosol] (R-SCE-429935)	0.527	3
UniProt:Q12035 FCF2			0.527	3
UniProt:P53276 UTP8			0.527	2
UniProt:Q08285 RRP40	2	RRP40 [nucleoplasm] (R-SCE-6791572) RRP40 [cytosol] (R-SCE-430017)	0.527	4
UniProt:P25368 RRP7	2	RRP7 [nucleoplasm] (R-SCE-6790601) RRP7 [nucleoplasm] (R-SCE-6790723)	0.527	2
UniProt:Q06287 EMG1	2	EMG1 [nucleoplasm] (R-SCE-6790671) EMG1 [nucleoplasm] (R-SCE-6790624)	0.527	3
UniProt:P53617	2	phospho-NRD1 [nucleoplasm] (R-SCE-8849461) NRD1 [nucleoplasm] (R-SCE-3900138)	0.527	3
UniProt:Q06512 NOC4	2	NOC4 [nucleoplasm] (R-SCE-6790676) NOC4 [nucleoplasm] (R-SCE-6790616)	0.527	3
UniProt:P53914 NAT10			0.527	3
UniProt:Q02354 UTP6	2	UTP6 [nucleoplasm] (R-SCE-6790683) UTP6 [nucleoplasm] (R-SCE-6790674)	0.527	2
UniProt:P33750 SOF1	2	SOF1 [nucleoplasm] (R-SCE-6790701) SOF1 [nucleoplasm] (R-SCE-6790673)	0.527	3
UniProt:P10592	20	SSA2 [cytosol] (R-SCE-264476-3) SSA2 [nucleoplasm] (R-SCE-6792605) SSA2 [cytosol] (R-SCE-3371410-3) SSA2 [cytosol] (R-SCE-3371408-3) SSA2 [cytosol] (R-SCE-6792602) SSA2 [nucleoplasm] (R-SCE-5082380-3) SSA2 [ficolin-1-rich granule lumen] (R-SCE-6801512-3) SSA2 [ficolin-1-rich granule lumen] (R-SCE-6801496) SSA2 [ficolin-1-rich granule lumen] (R-SCE-6801494-3) SSA2 [extracellular region] (R-SCE-6805872) SSA2 [extracellular region] (R-SCE-6806500-3) SSA2 [extracellular region] (R-SCE-6805936-3) SSA2 [secretory granule lumen] (R-SCE-6801530-3) SSA2 [secretory granule lumen] (R-SCE-6801472-3) SSA2 [nucleoplasm] (R-SCE-912480-3) SSA2 [nucleoplasm] (R-SCE-5082367-3) SSA2 [nucleoplasm] (R-SCE-5252082-3) SSA2 [nucleoplasm] (R-SCE-5252088-3) SSA2 [nucleoplasm] (R-SCE-5252009-3) SSA2 [nucleoplasm] (R-SCE-5252047-3)	0.527	2
UniProt:P42945 UTP10	2	UTP10 [nucleoplasm] (R-SCE-6790609) UTP10 [nucleoplasm] (R-SCE-6790721)	0.527	3
UniProt:P35194 UTP20	2	UTP20 [nucleoplasm] (R-SCE-6790649) UTP20 [nucleoplasm] (R-SCE-6790692)	0.527	2
UniProt:P25635 PWP2	2	PWP2 [nucleoplasm] (R-SCE-6790632) PWP2 [nucleoplasm] (R-SCE-6790680)	0.527	2
UniProt:P39076	3	CCT2 [extracellular region] (R-SCE-6806220) CCT2 [azurophil granule lumen] (R-SCE-6799356) CCT2 [cytosol] (R-SCE-390464)	0.527	2
UniProt:P53883	2	phospho-NOP13 [cytosol] (R-SCE-165773-2) NOP13 [cytosol] (R-SCE-72589-2)	0.527	3
UniProt:P53941 IMP4	2	IMP4 [nucleoplasm] (R-SCE-6790705) IMP4 [nucleoplasm] (R-SCE-6790690)	0.527	3
UniProt:Q05022 RRP5	2	RRP5 [nucleoplasm] (R-SCE-6790686) RRP5 [nucleoplasm] (R-SCE-6790646)	0.527	3
UniProt:P48234 NOL10			0.527	3
UniProt:Q04305 UTP15	2	UTP15 [nucleoplasm] (R-SCE-6790650) UTP15 [nucleoplasm] (R-SCE-6790678)	0.527	3
UniProt:Q06506 RRP9	2	RRP9 [nucleoplasm] (R-SCE-6790652) RRP9 [nucleoplasm] (R-SCE-6790682)	0.527	3
UniProt:P38996	2	NAB3 [nucleoplasm] (R-SCE-4570543) NAB3 [nucleoplasm] (R-SCE-71933)	0.527	3
UniProt:P38074	2	PRMT3 [cytosol] (R-SCE-8876692) PRMT1 [nucleoplasm] (R-SCE-3215140)	0.499	2

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