TRMT44 2'-O-methylates uridine-44 in tRNA(Ser)

Stable Identifier
R-HSA-6788707
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
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TRMT44 2'-O-methylates uridine-44 in tRNA(Ser)
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As inferred from the yeast homolog, TRMT44 methylates the 2' hydroxyl group of uridine-44 in tRNA(Ser). In yeast 2'-O-methyluridine-44 together with N(4)-acetylcytidine appears to be required to maintain abundance of tRNA(Ser).
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Event Information
Go Biological Process
tRNA methylation (0030488)
Catalyst Activity

tRNA(Ser) (uridine(44)-2'-O-)-methyltransferase activity of TRMT44 [cytosol]

Physical Entity
TRMT44 [cytosol] (Homo sapiens)
Activity
tRNA(Ser) (uridine(44)-2'-O-)-methyltransferase activity (GO:0141101)
Inferred From
TRM44 2'-O-methylates uridine-44 in tRNA(Ser) (Saccharomyces cerevisiae)
Authored
May, B  (2015-07-23)
Reviewed
Levinger, L  (2015-08-11)
Motorin, Y  (2015-08-25)
Jarrous, N  (2015-10-24)
Created
May, B  (2015-07-24)
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