Addition of a third glucose to the N-glycan skeleton by Alg10

Stable Identifier
R-SCE-449661
Type
Reaction [transition]
Species
Saccharomyces cerevisiae
Compartment
endoplasmic reticulum membrane, integral component of lumenal side of endoplasmic reticulum membrane
ReviewStatus
5/5
General
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PNG
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 | PPTX  | SBGN
Addition of a third glucose to the N-glycan skeleton by Alg10
The last glucose is added to the N-glycan precursor. This reaction occurs inside the ER lumen and uses Dol-P-Glc as the glucose donor. In yeast, this reaction is catalyzed by ALG10 (Burda P and Aebi M,1998).
Literature References
Participants
Input
Output
Catalyst Activity

dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity of DIE2 [endoplasmic reticulum membrane]

Physical Entity
DIE2 [endoplasmic reticulum membrane] (Saccharomyces cerevisiae)
Activity
dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity (GO:0004583)
Orthologous Events
Addition of a third glucose to the N-glycan precursor by an ALG10 homologue (Homo sapiens)
Authored
Dall'Olio, GM  (2009-11-10)
Reviewed
Gagneux, P  (2010-04-16)
Created
Jassal, B  (2009-12-03)
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