Reactome | Nascent F [endoplasmic reticulum membrane]

Nascent F [endoplasmic reticulum membrane]

Stable Identifier

R-RSY-9828695

Type

Protein [EntityWithAccessionedSequence]

Species

Human respiratory syncytial virus A

Compartment

endoplasmic reticulum membrane

Synonyms

Fusion glycoprotein F0, Protein F

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P03420 F

Gene Names

Chain

signal peptide:1-25, chain:26-574, chain:26-109, peptide:110-136, chain:137-574

Reference Genes

UCSC:P03420 F

Participates

as an output of

F mRNA is translated into nascent protein F (Homo sapiens)

as an input of

Nascent F signal peptide is cleaved at ER membrane (Homo sapiens)

Other forms of this molecule

F1-F2 [virion membrane]

N-glycan-PALM-F0 [trans-Golgi network membrane]

F1 [trans-Golgi network membrane]

F(110-136) [cytosol]

F2 [trans-Golgi network membrane]

N-glycan-F0 [endoplasmic reticulum-Golgi intermediate compartment membrane]

F0 [endoplasmic reticulum membrane]

F signal peptide [cytosol]

Crosslinked F1 [trans-Golgi network membrane]

Crosslinked F2 [trans-Golgi network membrane]

Crosslinked F1 [plasma membrane]

Crosslinked F2 [plasma membrane]

Crosslinked F1 [macropinosome membrane]

Crosslinked F2 [macropinosome membrane]

Disease

Name	Identifier	Synonyms
respiratory syncytial virus infectious disease	DOID:1273

Cross References

Mondo

0001577

HMDB Protein

HMDBP14050

PDB

6DC3, 4MMV, 6NTX, 5K6H, 4CCF, 5W23, 6VKE, 6EAD, 4JHW, 5U68, 6OE5, 6EAM, 6EAN, 5K6F, 6EAG, 6W52, 8PHI, 6EAH, 5KWW, 6EAI, 7LUE, 6APB, 5EA7, 4MMQ, 9B2X, 8ULJ, 6APD, 4MMS, 6DC5, 5TOJ, 6EAJ, 6EAK, 3RRT, 7TN1, 3O41, 8WZ3, 5EA3, 3KPE, 3IXT, 5EA5, 8WZ4, 2MDP, 6VKC, 5K6C, 5K6I, 8DG9, 8ULK, 5K6B, 6EAE, 6EAL, 6OE4, 9HVW, 4ZYP, 5K6G, 6EAF, 5UDC, 3RKI, 6OUS, 8WSQ, 7MMN, 5TPN, 6OJ7, 3O45, 5EA8, 7LVW, 4MMR, 3RRR, 4MMT, 5TOK, 8KG5, 6VKD, 4MMU, 6CXC, 5J3D, 5EA4, 5C69, 5C6B, 7MPG, 5EA6

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P03420 F	15	F1-F2 [virion membrane] (R-RSY-9835178) N-glycan-PALM-F0 [trans-Golgi network membrane] (R-RSY-9829024) F1 [trans-Golgi network membrane] (R-RSY-9829176) F(110-136) [cytosol] (R-RSY-9829179) F2 [trans-Golgi network membrane] (R-RSY-9829162) N-glycan-F0 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-RSY-9829051) F0 [endoplasmic reticulum membrane] (R-RSY-9829032) Nascent F [endoplasmic reticulum membrane] (R-RSY-9828695) F signal peptide [cytosol] (R-RSY-9829029) Crosslinked F1 [trans-Golgi network membrane] (R-RSY-9836300) Crosslinked F2 [trans-Golgi network membrane] (R-RSY-9836299) Crosslinked F1 [plasma membrane] (R-RSY-9836296) Crosslinked F2 [plasma membrane] (R-RSY-9836297) Crosslinked F1 [macropinosome membrane] (R-RSY-9837717) Crosslinked F2 [macropinosome membrane] (R-RSY-9837712)	0.884	8
IntAct:EBI-15820272 IQN57			0.618	3

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