Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
MDK:p-7Y ALK dimer [plasma membrane]
Stable Identifier
R-RNO-9700017
Type
Complex
Species
Rattus norvegicus
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Signal Transduction (Rattus norvegicus)
Signaling by Receptor Tyrosine Kinases (Rattus norvegicus)
Signaling by ALK (Rattus norvegicus)
ALK autophosphorylation (Rattus norvegicus)
Active ALK dimer [plasma membrane] (Rattus norvegicus)
MDK:p-7Y ALK dimer [plasma membrane] (Rattus norvegicus)
Active ALK binds JAK3 (Rattus norvegicus)
Active ALK dimer [plasma membrane] (Rattus norvegicus)
MDK:p-7Y ALK dimer [plasma membrane] (Rattus norvegicus)
Active ALK:JAK3 [plasma membrane] (Rattus norvegicus)
Active ALK dimer [plasma membrane] (Rattus norvegicus)
MDK:p-7Y ALK dimer [plasma membrane] (Rattus norvegicus)
Active ALK binds PLCG1 (Rattus norvegicus)
Active ALK dimer [plasma membrane] (Rattus norvegicus)
MDK:p-7Y ALK dimer [plasma membrane] (Rattus norvegicus)
Active ALK:PLCG1 [plasma membrane] (Rattus norvegicus)
Active ALK dimer [plasma membrane] (Rattus norvegicus)
MDK:p-7Y ALK dimer [plasma membrane] (Rattus norvegicus)
Active ALK binds SHC1 (Rattus norvegicus)
Active ALK dimer [plasma membrane] (Rattus norvegicus)
MDK:p-7Y ALK dimer [plasma membrane] (Rattus norvegicus)
Active ALK:SHC1 [plasma membrane] (Rattus norvegicus)
Active ALK dimer [plasma membrane] (Rattus norvegicus)
MDK:p-7Y ALK dimer [plasma membrane] (Rattus norvegicus)
Active ALK dimer binds IRS1 (Rattus norvegicus)
Active ALK dimer [plasma membrane] (Rattus norvegicus)
MDK:p-7Y ALK dimer [plasma membrane] (Rattus norvegicus)
Active ALK:IRS1 [plasma membrane] (Rattus norvegicus)
Active ALK dimer [plasma membrane] (Rattus norvegicus)
MDK:p-7Y ALK dimer [plasma membrane] (Rattus norvegicus)
Active ALK phosphorylates IRS1 (Rattus norvegicus)
Active ALK:IRS1 [plasma membrane] (Rattus norvegicus)
Active ALK dimer [plasma membrane] (Rattus norvegicus)
MDK:p-7Y ALK dimer [plasma membrane] (Rattus norvegicus)
Active ALK:pY-IRS1 [plasma membrane] (Rattus norvegicus)
Active ALK dimer [plasma membrane] (Rattus norvegicus)
MDK:p-7Y ALK dimer [plasma membrane] (Rattus norvegicus)
Active ALK phosphorylates JAK3 (Rattus norvegicus)
Active ALK:JAK3 [plasma membrane] (Rattus norvegicus)
Active ALK dimer [plasma membrane] (Rattus norvegicus)
MDK:p-7Y ALK dimer [plasma membrane] (Rattus norvegicus)
Active ALK:p-Y980 JAK3 [plasma membrane] (Rattus norvegicus)
Active ALK dimer [plasma membrane] (Rattus norvegicus)
MDK:p-7Y ALK dimer [plasma membrane] (Rattus norvegicus)
Active ALK phosphorylates PLCG1 (Rattus norvegicus)
Active ALK:PLCG1 [plasma membrane] (Rattus norvegicus)
Active ALK dimer [plasma membrane] (Rattus norvegicus)
MDK:p-7Y ALK dimer [plasma membrane] (Rattus norvegicus)
Active ALK:p-4Y PLCG1 [plasma membrane] (Rattus norvegicus)
Active ALK dimer [plasma membrane] (Rattus norvegicus)
MDK:p-7Y ALK dimer [plasma membrane] (Rattus norvegicus)
Active ALK phosphorylates SHC1 (Rattus norvegicus)
Active ALK:SHC1 [plasma membrane] (Rattus norvegicus)
Active ALK dimer [plasma membrane] (Rattus norvegicus)
MDK:p-7Y ALK dimer [plasma membrane] (Rattus norvegicus)
Active ALK:p-3Y SHC1 [plasma membrane] (Rattus norvegicus)
Active ALK dimer [plasma membrane] (Rattus norvegicus)
MDK:p-7Y ALK dimer [plasma membrane] (Rattus norvegicus)
Active ALK recruits PI3K (Rattus norvegicus)
Active ALK dimer [plasma membrane] (Rattus norvegicus)
MDK:p-7Y ALK dimer [plasma membrane] (Rattus norvegicus)
Active ALK:PI3K [plasma membrane] (Rattus norvegicus)
Active ALK dimer [plasma membrane] (Rattus norvegicus)
MDK:p-7Y ALK dimer [plasma membrane] (Rattus norvegicus)
MDK and PTN in ALK signaling (Rattus norvegicus)
PTPRZ dephosphorylates ligand-bound ALK dimers (Rattus norvegicus)
(PTN,MDK):p-7Y ALK dimer [plasma membrane] (Rattus norvegicus)
MDK:p-7Y ALK dimer [plasma membrane] (Rattus norvegicus)
PI3K synthesizes PIP3 downstream of ALK (Rattus norvegicus)
Active ALK:PI3K [plasma membrane] (Rattus norvegicus)
Active ALK dimer [plasma membrane] (Rattus norvegicus)
MDK:p-7Y ALK dimer [plasma membrane] (Rattus norvegicus)
PTPN6 dephosphorylates JAK3 (Rattus norvegicus)
Active ALK:JAK3 [plasma membrane] (Rattus norvegicus)
Active ALK dimer [plasma membrane] (Rattus norvegicus)
MDK:p-7Y ALK dimer [plasma membrane] (Rattus norvegicus)
Active ALK:p-Y980 JAK3 [plasma membrane] (Rattus norvegicus)
Active ALK dimer [plasma membrane] (Rattus norvegicus)
MDK:p-7Y ALK dimer [plasma membrane] (Rattus norvegicus)
STAT3 is phosphorylated downstream of active ALK (Rattus norvegicus)
Active ALK dimer [plasma membrane] (Rattus norvegicus)
MDK:p-7Y ALK dimer [plasma membrane] (Rattus norvegicus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
Mdk [extracellular region]
(Rattus norvegicus)
p-7Y ALK dimer [plasma membrane]
(Rattus norvegicus)
Participates
as a member of
(PTN,MDK):p-7Y ALK dimer [plasma membrane] (Rattus norvegicus)
as a candidate of
Active ALK dimer [plasma membrane] (Rattus norvegicus)
Inferred From
MDK:p-7Y ALK dimer [plasma membrane]
(Homo sapiens)
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text