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Active ALK dimer [plasma membrane]
Stable Identifier
R-RNO-9850879
Type
Set [CandidateSet]
Species
Rattus norvegicus
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Signal Transduction (Rattus norvegicus)
Signaling by Receptor Tyrosine Kinases (Rattus norvegicus)
Signaling by ALK (Rattus norvegicus)
ALK autophosphorylation (Rattus norvegicus)
Active ALK dimer [plasma membrane] (Rattus norvegicus)
Active ALK binds JAK3 (Rattus norvegicus)
Active ALK dimer [plasma membrane] (Rattus norvegicus)
Active ALK:JAK3 [plasma membrane] (Rattus norvegicus)
Active ALK dimer [plasma membrane] (Rattus norvegicus)
Active ALK binds PLCG1 (Rattus norvegicus)
Active ALK dimer [plasma membrane] (Rattus norvegicus)
Active ALK:PLCG1 [plasma membrane] (Rattus norvegicus)
Active ALK dimer [plasma membrane] (Rattus norvegicus)
Active ALK binds SHC1 (Rattus norvegicus)
Active ALK dimer [plasma membrane] (Rattus norvegicus)
Active ALK:SHC1 [plasma membrane] (Rattus norvegicus)
Active ALK dimer [plasma membrane] (Rattus norvegicus)
Active ALK dimer binds IRS1 (Rattus norvegicus)
Active ALK dimer [plasma membrane] (Rattus norvegicus)
Active ALK:IRS1 [plasma membrane] (Rattus norvegicus)
Active ALK dimer [plasma membrane] (Rattus norvegicus)
Active ALK phosphorylates IRS1 (Rattus norvegicus)
Active ALK:IRS1 [plasma membrane] (Rattus norvegicus)
Active ALK dimer [plasma membrane] (Rattus norvegicus)
Active ALK:pY-IRS1 [plasma membrane] (Rattus norvegicus)
Active ALK dimer [plasma membrane] (Rattus norvegicus)
Active ALK phosphorylates JAK3 (Rattus norvegicus)
Active ALK:JAK3 [plasma membrane] (Rattus norvegicus)
Active ALK dimer [plasma membrane] (Rattus norvegicus)
Active ALK:p-Y980 JAK3 [plasma membrane] (Rattus norvegicus)
Active ALK dimer [plasma membrane] (Rattus norvegicus)
Active ALK phosphorylates PLCG1 (Rattus norvegicus)
Active ALK:PLCG1 [plasma membrane] (Rattus norvegicus)
Active ALK dimer [plasma membrane] (Rattus norvegicus)
Active ALK:p-4Y PLCG1 [plasma membrane] (Rattus norvegicus)
Active ALK dimer [plasma membrane] (Rattus norvegicus)
Active ALK phosphorylates SHC1 (Rattus norvegicus)
Active ALK:SHC1 [plasma membrane] (Rattus norvegicus)
Active ALK dimer [plasma membrane] (Rattus norvegicus)
Active ALK:p-3Y SHC1 [plasma membrane] (Rattus norvegicus)
Active ALK dimer [plasma membrane] (Rattus norvegicus)
Active ALK recruits PI3K (Rattus norvegicus)
Active ALK dimer [plasma membrane] (Rattus norvegicus)
Active ALK:PI3K [plasma membrane] (Rattus norvegicus)
Active ALK dimer [plasma membrane] (Rattus norvegicus)
PI3K synthesizes PIP3 downstream of ALK (Rattus norvegicus)
Active ALK:PI3K [plasma membrane] (Rattus norvegicus)
Active ALK dimer [plasma membrane] (Rattus norvegicus)
PTPN6 dephosphorylates JAK3 (Rattus norvegicus)
Active ALK:JAK3 [plasma membrane] (Rattus norvegicus)
Active ALK dimer [plasma membrane] (Rattus norvegicus)
Active ALK:p-Y980 JAK3 [plasma membrane] (Rattus norvegicus)
Active ALK dimer [plasma membrane] (Rattus norvegicus)
STAT3 is phosphorylated downstream of active ALK (Rattus norvegicus)
Active ALK dimer [plasma membrane] (Rattus norvegicus)
Participants
members
p-7Y ALK dimer:ALKAL2:(ALKAL1) [plasma membrane]
(Rattus norvegicus)
candidates
MDK:p-7Y ALK dimer [plasma membrane]
(Rattus norvegicus)
PTN:p-7Y ALK dimer [plasma membrane]
(Rattus norvegicus)
Participates
as an input of
Active ALK recruits PI3K (Rattus norvegicus)
Active ALK binds PLCG1 (Rattus norvegicus)
Active ALK dimer binds IRS1 (Rattus norvegicus)
Active ALK binds SHC1 (Rattus norvegicus)
Active ALK binds JAK3 (Rattus norvegicus)
STAT3 is phosphorylated downstream of active ALK (Rattus norvegicus)
as a component of
Active ALK:PI3K [plasma membrane] (Rattus norvegicus)
Active ALK:p-4Y PLCG1 [plasma membrane] (Rattus norvegicus)
Active ALK:PLCG1 [plasma membrane] (Rattus norvegicus)
Active ALK:pY-IRS1 [plasma membrane] (Rattus norvegicus)
Active ALK:IRS1 [plasma membrane] (Rattus norvegicus)
Active ALK:p-3Y SHC1 [plasma membrane] (Rattus norvegicus)
Active ALK:SHC1 [plasma membrane] (Rattus norvegicus)
Active ALK:JAK3 [plasma membrane] (Rattus norvegicus)
Active ALK:p-Y980 JAK3 [plasma membrane] (Rattus norvegicus)
as an output of
ALK autophosphorylation (Rattus norvegicus)
Inferred From
Active ALK dimer [plasma membrane]
(Homo sapiens)
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