In rat neurons, Actn2 (alpha-actinin-2) directly binds to GluN1 (Grin1) subunit of the NMDA receptor, but can also bind to GluN2B (Grin2b). Binding to Actn2 anchors NMDA receptors to the actin cytoskeleton (Wyszynski et al. 1997).
Beggs, AH, Wyszynski, M, Lin, J, Craig, AM, Sheng, M, Nigh, E, Rao, A
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