Mecp2 mRNA translation is inhibited by miR-132

Stable Identifier
R-RNO-9021293
Type
Reaction [omitted]
Species
Rattus norvegicus
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General
SVG |   | PPTX  | SBGN
Mecp2 mRNA translation is inhibited by miR-132

Rat miR-132 reduces both mRNA and protein levels of Mecp2. miR-132 is therefore expected to function in the context of the endonucleolytic RISC, and possibly also non-endonucleolytic RISC. MicroRNA miR-132 is complementary to the 3'UTR of long Mecp2 transcripts (>10 kb), which are predominantly expressed in the brain (Su et al. 2015).

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