Mecp2 mRNA binds miR-132 RISC

Stable Identifier
R-RNO-9021287
Type
Reaction [binding]
Species
Rattus norvegicus
Compartment
General
SVG |   | PPTX  | SBGN
Mecp2 mRNA binds miR-132 RISC

Rat microRNA miR-132, similar to mouse and human miR-132, is complementary to the 3'UTR of long Mecp2 transcripts (>10 kb), which are predominantly expressed in the brain. miR-132 reduces both mRNA and protein levels of Mecp2 and was confirmed to be specific for Mecp2 mRNA by the 3'UTR-luciferase reporter gene assay (Su et al. 2015).

Literature References
Participants
Orthologous Events
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Reviewed
Created