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IL12A:EBI3:IL12RB2:p-JAK1:IL27RA:p-JAK2 [plasma membrane]
Stable Identifier
R-RNO-8951178
Type
Complex
Species
Rattus norvegicus
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Immune System (Rattus norvegicus)
Cytokine Signaling in Immune system (Rattus norvegicus)
Signaling by Interleukins (Rattus norvegicus)
Interleukin-12 family signaling (Rattus norvegicus)
Interleukin-35 Signalling (Rattus norvegicus)
JAK1,JAK2 bound to IL27RA:IL12RB2 receptor phosphorylate STAT1,STAT3 (Rattus norvegicus)
IL-35:IL27RA:p-JAK1:IL12RB2:p-JAK2:p-STAT1:p-STAT3 [plasma membrane] (Rattus norvegicus)
IL12A:EBI3:IL12RB2:p-JAK1:IL27RA:p-JAK2 [plasma membrane] (Rattus norvegicus)
IL35:IL27RA:p-JAK1:IL12RB2:p-JAK2:STAT1:STAT3 [plasma membrane] (Rattus norvegicus)
IL12A:EBI3:IL12RB2:p-JAK1:IL27RA:p-JAK2 [plasma membrane] (Rattus norvegicus)
STAT1,STAT3 associate with IL27RA:IL12RB2 receptor (Rattus norvegicus)
IL35:IL27RA:p-JAK1:IL12RB2:p-JAK2:STAT1:STAT3 [plasma membrane] (Rattus norvegicus)
IL12A:EBI3:IL12RB2:p-JAK1:IL27RA:p-JAK2 [plasma membrane] (Rattus norvegicus)
p-STAT1, p-STAT3 dissociate from IL27RA:IL12RB2 receptor (Rattus norvegicus)
IL-35:IL27RA:p-JAK1:IL12RB2:p-JAK2:p-STAT1:p-STAT3 [plasma membrane] (Rattus norvegicus)
IL12A:EBI3:IL12RB2:p-JAK1:IL27RA:p-JAK2 [plasma membrane] (Rattus norvegicus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
Ghost homologue of IL27RA [plasma membrane]
(Rattus norvegicus)
Il12rb2 [plasma membrane]
(Rattus norvegicus)
IL35 [extracellular region]
(Rattus norvegicus)
phospho-p-JAK1 [cytosol]
(Rattus norvegicus)
phospho-p-JAK2 [cytosol]
(Rattus norvegicus)
Participates
as a component of
IL-35:IL27RA:p-JAK1:IL12RB2:p-JAK2:p-STAT1:p-STAT3 [plasma membrane] (Rattus norvegicus)
IL35:IL27RA:p-JAK1:IL12RB2:p-JAK2:STAT1:STAT3 [plasma membrane] (Rattus norvegicus)
Inferred From
IL12A:EBI3:IL12RB2:p-JAK1:IL27RA:p-JAK2 [plasma membrane]
(Homo sapiens)
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