Experimental evidence in samples of patients with AML, shows that 32D myeloid cells transformed by IL-27RA (subunit which can be part of the Interleukin-35 receptor or Interleukin-27 receptor) contain elevated levels of activated forms of various signaling proteins incluiding Jak1, Jak2, Stat1, Stat3, (PMID:18003935).
Pradhan, A, Lambert, QT, Reuther, GW
Delgoffe, GM, Murray, PJ, Drake, CG, Satoskar, AR, Fairweather, D, Guy, CS, Hunter, CA, Vignali, DA, Garcia, KC, Chaturvedi, V, Collison, LW, Vignali, KM
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