Reactome | Pou2f1 [nucleoplasm]

Pou2f1 [nucleoplasm]

Stable Identifier

R-RNO-83836

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

nucleoplasm

Synonyms

POU2F1, F1LRD7

Locations in the PathwayBrowser

Expand all

Gene expression (Transcription) (Rattus norvegicus)

- RNA Polymerase II Transcription (Rattus norvegicus)
  - RNA polymerase II transcribes snRNA genes (Rattus norvegicus)
    - CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter (Rattus norvegicus)
      - RNA polymerase II (phosphoserine-5,7):Initiation factors:CDK7:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        POU2F1,2 [nucleoplasm] (Rattus norvegicus)
        
        Pou2f1 [nucleoplasm] (Rattus norvegicus)
      - RNA polymerase II (unphosphorylated):Initiation factors at promoter of snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        POU2F1,2 [nucleoplasm] (Rattus norvegicus)
        
        Pou2f1 [nucleoplasm] (Rattus norvegicus)
    - General transcription factors bind SNAPc:POU2F1:ZNF143:snRNA gene (Rattus norvegicus)
      - Initiation factors:CDK7:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        POU2F1,2 [nucleoplasm] (Rattus norvegicus)
        
        Pou2f1 [nucleoplasm] (Rattus norvegicus)
      - SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        POU2F1,2 [nucleoplasm] (Rattus norvegicus)
        
        Pou2f1 [nucleoplasm] (Rattus norvegicus)
    - Integrator complex processes the 3' end of snRNA (Rattus norvegicus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        POU2F1,2 [nucleoplasm] (Rattus norvegicus)
        
        Pou2f1 [nucleoplasm] (Rattus norvegicus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:Initiation factors:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        POU2F1,2 [nucleoplasm] (Rattus norvegicus)
        
        Pou2f1 [nucleoplasm] (Rattus norvegicus)
    - Pre-snRNA is elongated and capped with 7-methylguanosine (Rattus norvegicus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        POU2F1,2 [nucleoplasm] (Rattus norvegicus)
        
        Pou2f1 [nucleoplasm] (Rattus norvegicus)
      - RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        POU2F1,2 [nucleoplasm] (Rattus norvegicus)
        
        Pou2f1 [nucleoplasm] (Rattus norvegicus)
    - Pre-snRNA transcript initiation, Integrator binding, LEC binding (Rattus norvegicus)
      - RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        POU2F1,2 [nucleoplasm] (Rattus norvegicus)
        
        Pou2f1 [nucleoplasm] (Rattus norvegicus)
      - RPAP2:RPRD1A,B:RPRD2:RNA polymerase II (phosphoserine-5,7):Initiation factors:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        POU2F1,2 [nucleoplasm] (Rattus norvegicus)
        
        Pou2f1 [nucleoplasm] (Rattus norvegicus)
    - RNA polymerase II binds initiation factors at promoter of snRNA gene (U1, U2, U4, U4atac, U5, U11, U12) (Rattus norvegicus)
      - Initiation factors:CDK7:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        POU2F1,2 [nucleoplasm] (Rattus norvegicus)
        
        Pou2f1 [nucleoplasm] (Rattus norvegicus)
      - RNA polymerase II (unphosphorylated):Initiation factors at promoter of snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        POU2F1,2 [nucleoplasm] (Rattus norvegicus)
        
        Pou2f1 [nucleoplasm] (Rattus norvegicus)
    - RPAP2 binds RNA polymerase II phosphorylated at serine-7 residues of heptad repeats in the C-terminal domain (Rattus norvegicus)
      - RNA polymerase II (phosphoserine-5,7):Initiation factors:CDK7:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        POU2F1,2 [nucleoplasm] (Rattus norvegicus)
        
        Pou2f1 [nucleoplasm] (Rattus norvegicus)
      - RPAP2:RPRD1A,B:RPRD2:RNA polymerase II (phosphoserine-5,7):Initiation factors:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        POU2F1,2 [nucleoplasm] (Rattus norvegicus)
        
        Pou2f1 [nucleoplasm] (Rattus norvegicus)
- RNA Polymerase III Transcription (Rattus norvegicus)
  - RNA Polymerase III Transcription Initiation (Rattus norvegicus)
    - RNA Polymerase III Transcription Initiation From Type 3 Promoter (Rattus norvegicus)
      - Binding of TFIIIB to SNAPc:Oct-1:Staf:Type 3 Promoter Complex (Rattus norvegicus)
        
        SNAPc:Oct-1:Staf:Type 3 Promoter Complex [nucleoplasm] (Rattus norvegicus)
        
        Pou2f1 [nucleoplasm] (Rattus norvegicus)
        
        TFIIIB:SNAPc:Oct-1:Staf:Type 3 Promoter Complex [nucleoplasm] (Rattus norvegicus)
        
        SNAPc:Oct-1:Staf:Type 3 Promoter Complex [nucleoplasm] (Rattus norvegicus)
        
        Pou2f1 [nucleoplasm] (Rattus norvegicus)
      - Recruitment of RNA Polymerase III to TFIIIB:SNAPc:Type 3 Promoter Complex (Rattus norvegicus)
        
        RNA Polymerase III:TFIIIB:SNAPc:Type 3 Promoter Complex [nucleoplasm] (Rattus norvegicus)
        
        TFIIIB:SNAPc:Oct-1:Staf:Type 3 Promoter Complex [nucleoplasm] (Rattus norvegicus)
        
        SNAPc:Oct-1:Staf:Type 3 Promoter Complex [nucleoplasm] (Rattus norvegicus)
        
        Pou2f1 [nucleoplasm] (Rattus norvegicus)
        
        TFIIIB:SNAPc:Oct-1:Staf:Type 3 Promoter Complex [nucleoplasm] (Rattus norvegicus)
        
        SNAPc:Oct-1:Staf:Type 3 Promoter Complex [nucleoplasm] (Rattus norvegicus)
        
        Pou2f1 [nucleoplasm] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:F1LRD7

Gene Names

Pou2f1

Reference Genes

BioGPS Gene:171068 Pou2f1

ENSEMBL:ENSRNOG00000003581

ENSEMBL:ENSRNOG00000003581 Pou2f1

KEGG Gene (Rattus norvegicus):171068 Pou2f1

Monarch:171068 Pou2f1

NCBI Gene:171068 Pou2f1

Reference Transcript

RefSeq:NM_001100639.1 Pou2f1

Other Identifiers

10769555

1370995_at

171068

17686261

5676754

5701333

5891936

6017345

6063169

6174468

6280348

6338160

6367083

6387534

6432464

6439278

6441031

6452860

6582876

6612473

6627911

6650232

6656511

6682269

6705755

6707373

A_43_P15804

D12978cds_s_at

GE20872

GE21557

GO:0000978

GO:0000979

GO:0000981

GO:0003674

GO:0003677

GO:0003700

GO:0005575

GO:0005622

GO:0005634

GO:0005654

GO:0005737

GO:0005783

GO:0006355

GO:0008150

GO:0009058

GO:0032991

GO:0034641

GO:0043226

GO:0043231

GO:0043565

GO:0045892

GO:0045944

GO:0090575

PH_rn_0015470

U17013_at

Participant Of

hasComponent

SNAPc:Oct-1:Staf:Type 3 Promoter Complex [nucleoplasm]

hasMember

POU2F1,2 [nucleoplasm]

Inferred From

POU2F1 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_001094109.1

Ensembl

ENSRNOT00000047488, ENSRNOG00000003581, ENSRNOP00000044416

RGD

621689

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