Reactome | Cope [transport vesicle]

Cope [transport vesicle]

Stable Identifier

R-RNO-6808745

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

transport vesicle

Synonyms

COPE, A0A8I6A9R8

Locations in the PathwayBrowser

Expand all

Metabolism of proteins (Rattus norvegicus)

- Post-translational protein modification (Rattus norvegicus)
  - Asparagine N-linked glycosylation (Rattus norvegicus)
    - Transport to the Golgi and subsequent modification (Rattus norvegicus)
      - ER to Golgi Anterograde Transport (Rattus norvegicus)
        
        COPI-mediated anterograde transport (Rattus norvegicus)
        
        ARFGAPs stimulate ARF GTPase activity (Rattus norvegicus)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Rattus norvegicus)
        
        RAB1:GTP:USO1:coatomer [transport vesicle] (Rattus norvegicus)
        
        coatomer [transport vesicle] (Rattus norvegicus)
        
        trimeric coatomer complex [transport vesicle] (Rattus norvegicus)
        
        Cope [transport vesicle] (Rattus norvegicus)
        
        ERGIC-to-Golgi vesicles bind dynein:dynactin (Rattus norvegicus)
        
        RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Rattus norvegicus)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Rattus norvegicus)
        
        RAB1:GTP:USO1:coatomer [transport vesicle] (Rattus norvegicus)
        
        coatomer [transport vesicle] (Rattus norvegicus)
        
        trimeric coatomer complex [transport vesicle] (Rattus norvegicus)
        
        Cope [transport vesicle] (Rattus norvegicus)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Rattus norvegicus)
        
        RAB1:GTP:USO1:coatomer [transport vesicle] (Rattus norvegicus)
        
        coatomer [transport vesicle] (Rattus norvegicus)
        
        trimeric coatomer complex [transport vesicle] (Rattus norvegicus)
        
        Cope [transport vesicle] (Rattus norvegicus)
        
        Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex (Rattus norvegicus)
        
        RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Rattus norvegicus)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Rattus norvegicus)
        
        RAB1:GTP:USO1:coatomer [transport vesicle] (Rattus norvegicus)
        
        coatomer [transport vesicle] (Rattus norvegicus)
        
        trimeric coatomer complex [transport vesicle] (Rattus norvegicus)
        
        Cope [transport vesicle] (Rattus norvegicus)

Vesicle-mediated transport (Rattus norvegicus)

- Membrane Trafficking (Rattus norvegicus)
  - ER to Golgi Anterograde Transport (Rattus norvegicus)
    - COPI-mediated anterograde transport (Rattus norvegicus)
      - ARFGAPs stimulate ARF GTPase activity (Rattus norvegicus)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Rattus norvegicus)
        
        RAB1:GTP:USO1:coatomer [transport vesicle] (Rattus norvegicus)
        
        coatomer [transport vesicle] (Rattus norvegicus)
        
        trimeric coatomer complex [transport vesicle] (Rattus norvegicus)
        
        Cope [transport vesicle] (Rattus norvegicus)
      - ERGIC-to-Golgi vesicles bind dynein:dynactin (Rattus norvegicus)
        
        RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Rattus norvegicus)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Rattus norvegicus)
        
        RAB1:GTP:USO1:coatomer [transport vesicle] (Rattus norvegicus)
        
        coatomer [transport vesicle] (Rattus norvegicus)
        
        trimeric coatomer complex [transport vesicle] (Rattus norvegicus)
        
        Cope [transport vesicle] (Rattus norvegicus)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Rattus norvegicus)
        
        RAB1:GTP:USO1:coatomer [transport vesicle] (Rattus norvegicus)
        
        coatomer [transport vesicle] (Rattus norvegicus)
        
        trimeric coatomer complex [transport vesicle] (Rattus norvegicus)
        
        Cope [transport vesicle] (Rattus norvegicus)
      - Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex (Rattus norvegicus)
        
        RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Rattus norvegicus)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Rattus norvegicus)
        
        RAB1:GTP:USO1:coatomer [transport vesicle] (Rattus norvegicus)
        
        coatomer [transport vesicle] (Rattus norvegicus)
        
        trimeric coatomer complex [transport vesicle] (Rattus norvegicus)
        
        Cope [transport vesicle] (Rattus norvegicus)
  - Intra-Golgi and retrograde Golgi-to-ER traffic (Rattus norvegicus)
    - Golgi-to-ER retrograde transport (Rattus norvegicus)
      - COPI-dependent Golgi-to-ER retrograde traffic (Rattus norvegicus)
        
        ARFGAPs stimulate ARF GTPase activity at the Golgi membrane (Rattus norvegicus)
        
        RAB1:GTP:coatomer:p24 dimers:SEC22B:cargo [transport vesicle] (Rattus norvegicus)
        
        coatomer [transport vesicle] (Rattus norvegicus)
        
        trimeric coatomer complex [transport vesicle] (Rattus norvegicus)
        
        Cope [transport vesicle] (Rattus norvegicus)
        
        Retrograde COPI vesicles bind kinesin and microtubules (Rattus norvegicus)
        
        RAB1:GTP:coatomer:p24 dimers:SEC22B:cargo [transport vesicle] (Rattus norvegicus)
        
        coatomer [transport vesicle] (Rattus norvegicus)
        
        trimeric coatomer complex [transport vesicle] (Rattus norvegicus)
        
        Cope [transport vesicle] (Rattus norvegicus)
        
        RAB1:GTP:coatomer:p24 dimers:SEC22B:kinesins:microtubules [transport vesicle] (Rattus norvegicus)
        
        RAB1:GTP:coatomer:p24 dimers:SEC22B:cargo [transport vesicle] (Rattus norvegicus)
        
        coatomer [transport vesicle] (Rattus norvegicus)
        
        trimeric coatomer complex [transport vesicle] (Rattus norvegicus)
        
        Cope [transport vesicle] (Rattus norvegicus)
        
        Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs (Rattus norvegicus)
        
        RAB1:GTP:coatomer:p24 dimers:SEC22B:kinesins:microtubules [transport vesicle] (Rattus norvegicus)
        
        RAB1:GTP:coatomer:p24 dimers:SEC22B:cargo [transport vesicle] (Rattus norvegicus)
        
        coatomer [transport vesicle] (Rattus norvegicus)
        
        trimeric coatomer complex [transport vesicle] (Rattus norvegicus)
        
        Cope [transport vesicle] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:A0A8I6A9R8

Gene Names

Cope

Reference Genes

BioGPS Gene:290659 Cope

ENSEMBL:ENSRNOG00000020178

KEGG:rno:290659 Cope

Monarch:290659 Cope

NCBI Gene:290659 Cope

UCSC:A0A8I6A9R8 Cope

Reference Transcript

RefSeq:NM_001399438.1 Cope

Other Identifiers

10791022

1371802_at

17710958

290659

5765787

5784583

5823437

5849292

5923552

6140454

6331380

6445201

6546690

6549831

6574068

6589929

6719023

A_44_P995058

A_64_P025217

A_64_P189793

GE12951

GO:0005198

GO:0005515

GO:0005654

GO:0005794

GO:0006890

GO:0016192

ILMN_1371140

PH_rn_0008120

PH_rn_0019963

rc_AA963071_at

Participates

as a component of

trimeric coatomer complex [transport vesicle] (Rattus norvegicus)

Other forms of this molecule

Cope [endoplasmic reticulum membrane]

Cope [Golgi membrane]

Cope [cytosol]

Inferred From

COPE [transport vesicle] (Homo sapiens)

Cross References

RefSeq

NP_001386367.1

ENSEMBL

ENSRNOT00000105529, ENSRNOG00000020178, ENSRNOP00000089951

RGD

1306785

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