Reactome | CCNT1 [nucleoplasm]

CCNT1 [nucleoplasm]

Stable Identifier

R-RNO-51611

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

nucleoplasm

Synonyms

A0A0G2JXM2

Locations in the PathwayBrowser

Expand all

Signal Transduction (Rattus norvegicus)

- Signaling by Nuclear Receptors (Rattus norvegicus)
  - ESR-mediated signaling (Rattus norvegicus)
    - Estrogen-dependent gene expression (Rattus norvegicus)
      - ESR1:ESTG:P-TEFb recruited to paused RNA polymerase II on MYB gene (Rattus norvegicus)
        
        ESR1:ESTG:P-TEFb [nucleoplasm] (Rattus norvegicus)
        
        P-TEFb(Cyclin T1:Cdk9) complex [nucleoplasm] (Rattus norvegicus)
        
        CCNT1 [nucleoplasm] (Rattus norvegicus)
        
        MYB gene:hypophosphorylated RNA polymerase II:TFIIF:ESR1:ESTG:P-TEFb [nucleoplasm] (Rattus norvegicus)
        
        ESR1:ESTG:P-TEFb [nucleoplasm] (Rattus norvegicus)
        
        P-TEFb(Cyclin T1:Cdk9) complex [nucleoplasm] (Rattus norvegicus)
        
        CCNT1 [nucleoplasm] (Rattus norvegicus)
      - p-TEFb phosphorylates serine 2 in RNA polymerase II CTD (Rattus norvegicus)
        
        MYB gene:hyperphosphorylated RNA polymerase II:TFIIF:ESR1:ESTG:P-TEFb [nucleoplasm] (Rattus norvegicus)
        
        ESR1:ESTG:P-TEFb [nucleoplasm] (Rattus norvegicus)
        
        P-TEFb(Cyclin T1:Cdk9) complex [nucleoplasm] (Rattus norvegicus)
        
        CCNT1 [nucleoplasm] (Rattus norvegicus)
        
        MYB gene:hypophosphorylated RNA polymerase II:TFIIF:ESR1:ESTG:P-TEFb [nucleoplasm] (Rattus norvegicus)
        
        ESR1:ESTG:P-TEFb [nucleoplasm] (Rattus norvegicus)
        
        P-TEFb(Cyclin T1:Cdk9) complex [nucleoplasm] (Rattus norvegicus)
        
        CCNT1 [nucleoplasm] (Rattus norvegicus)
- Signaling by TGFB family members (Rattus norvegicus)
  - Signaling by TGF-beta Receptor Complex (Rattus norvegicus)
    - Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (Rattus norvegicus)
      - SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription (Rattus norvegicus)
        
        Phosphorylation of SMAD2 and SMAD3 linker regions by CDK8 or CDK9 (Rattus norvegicus)
        
        CDK8:CCNC/ CDK9:CCNT [nucleoplasm] (Rattus norvegicus)
        
        P-TEFb complex [nucleoplasm] (Rattus norvegicus)
        
        CCNT1,CCNT2,CCNK [nucleoplasm] (Rattus norvegicus)
        
        CCNT1 [nucleoplasm] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:A0A0G2JXM2

Reference Genes

ENSEMBL:ENSRNOG00000053054

ENSEMBL:ENSRNOG00000055738

UCSC:A0A0G2JXM2

Other Identifiers

10906872

1390410_at

17840726

315291

5707753

5741857

5798942

5809823

5844245

5862998

5864046

5903785

5916946

5979998

5995575

6053620

6071555

6083533

6089647

6093660

6104659

6119301

6141256

6314248

6399589

6428729

6434875

6435482

6563685

6681013

6713593

6734885

A_44_P416178

A_44_P504221

GO:0000976

GO:0003677

GO:0003682

GO:0003723

GO:0005634

GO:0005654

GO:0005829

GO:0006355

GO:0006357

GO:0008024

GO:0016538

GO:0017069

GO:0019901

GO:0032968

GO:0043923

GO:0045944

GO:0060090

GO:0061575

GO:0070063

GO:0070691

GO:0097322

GO:0098772

GO:0140297

GO:0140693

ILMN_1369043

ILMN_1530321

PH_rn_0010504

rc_AA963369_at

Participates

as a component of

P-TEFb(Cyclin T1:Cdk9) complex [nucleoplasm] (Rattus norvegicus)

as a member of

CCNT1,CCNT2,CCNK [nucleoplasm] (Rattus norvegicus)

Inferred From

CCNT1 [nucleoplasm] (Homo sapiens)

Cross References

ENSEMBL

ENSRNOP00000106394, ENSRNOT00000129768, ENSRNOG00000053054

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