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PI3K beta [cytosol]
Stable Identifier
R-RNO-437110
Type
Complex
Species
Rattus norvegicus
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Developmental Biology (Rattus norvegicus)
Nervous system development (Rattus norvegicus)
Axon guidance (Rattus norvegicus)
RET signaling (Rattus norvegicus)
p-5Y-GAB in the RET-GRB2-GAB complexes binds p85-PI3K (Rattus norvegicus)
2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1:p-5Y-GAB1,p-5Y-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Rattus norvegicus)
p85-containing Class 1A PI3Ks [cytosol] (Rattus norvegicus)
PI3K beta [cytosol] (Rattus norvegicus)
p85-containing Class 1A PI3Ks [cytosol] (Rattus norvegicus)
PI3K beta [cytosol] (Rattus norvegicus)
Hemostasis (Rattus norvegicus)
Platelet activation, signaling and aggregation (Rattus norvegicus)
GPVI-mediated activation cascade (Rattus norvegicus)
GPVI stimulates PI3K beta, gamma (Rattus norvegicus)
PI3K beta [cytosol] (Rattus norvegicus)
PI3K alpha, beta, gamma convert PIP2 to PIP3 (Rattus norvegicus)
PI3K alpha, beta, gamma [cytosol] (Rattus norvegicus)
PI3K beta [cytosol] (Rattus norvegicus)
Immune System (Rattus norvegicus)
Cytokine Signaling in Immune system (Rattus norvegicus)
Signaling by Interleukins (Rattus norvegicus)
Interleukin-2 family signaling (Rattus norvegicus)
Interleukin receptor SHC signaling (Rattus norvegicus)
Gab2 binds the p85 subunit of Class 1A PI3 kinases (Rattus norvegicus)
Interleukin receptor complexes with activated Shc:GRB2:p-GAB2:p85-containing Class 1 PI3Ks [plasma membrane] (Rattus norvegicus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Rattus norvegicus)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Rattus norvegicus)
p85-containing Class 1A PI3Ks [cytosol] (Rattus norvegicus)
PI3K beta [cytosol] (Rattus norvegicus)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Rattus norvegicus)
p85-containing Class 1A PI3Ks [cytosol] (Rattus norvegicus)
PI3K beta [cytosol] (Rattus norvegicus)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Rattus norvegicus)
p85-containing Class 1A PI3Ks [cytosol] (Rattus norvegicus)
PI3K beta [cytosol] (Rattus norvegicus)
IL2:IL2R trimer p(Y338) beta subunit:p-SHC:GRB2:GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Rattus norvegicus)
p85-containing Class 1A PI3Ks [cytosol] (Rattus norvegicus)
PI3K beta [cytosol] (Rattus norvegicus)
p85-containing Class 1A PI3Ks [cytosol] (Rattus norvegicus)
PI3K beta [cytosol] (Rattus norvegicus)
Interleukin-3, Interleukin-5 and GM-CSF signaling (Rattus norvegicus)
14-3-3 zeta binding allows recruitment of PI3K (Rattus norvegicus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(S589)-Bc:14-3-3 zeta:p85-containing Class 1A PI3Ks [plasma membrane] (Rattus norvegicus)
p85-containing Class 1A PI3Ks [cytosol] (Rattus norvegicus)
PI3K beta [cytosol] (Rattus norvegicus)
p85-containing Class 1A PI3Ks [cytosol] (Rattus norvegicus)
PI3K beta [cytosol] (Rattus norvegicus)
Interleukin receptor SHC signaling (Rattus norvegicus)
Gab2 binds the p85 subunit of Class 1A PI3 kinases (Rattus norvegicus)
Interleukin receptor complexes with activated Shc:GRB2:p-GAB2:p85-containing Class 1 PI3Ks [plasma membrane] (Rattus norvegicus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Rattus norvegicus)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Rattus norvegicus)
p85-containing Class 1A PI3Ks [cytosol] (Rattus norvegicus)
PI3K beta [cytosol] (Rattus norvegicus)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Rattus norvegicus)
p85-containing Class 1A PI3Ks [cytosol] (Rattus norvegicus)
PI3K beta [cytosol] (Rattus norvegicus)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Rattus norvegicus)
p85-containing Class 1A PI3Ks [cytosol] (Rattus norvegicus)
PI3K beta [cytosol] (Rattus norvegicus)
IL2:IL2R trimer p(Y338) beta subunit:p-SHC:GRB2:GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Rattus norvegicus)
p85-containing Class 1A PI3Ks [cytosol] (Rattus norvegicus)
PI3K beta [cytosol] (Rattus norvegicus)
p85-containing Class 1A PI3Ks [cytosol] (Rattus norvegicus)
PI3K beta [cytosol] (Rattus norvegicus)
Regulation of signaling by CBL (Rattus norvegicus)
CBL ubiquitinates PI3K (Rattus norvegicus)
FYN-like kinases:p(Y731)-CBL:GRB2:p85-containing Class 1A PI3Ks [cytosol] (Rattus norvegicus)
p85-containing Class 1A PI3Ks [cytosol] (Rattus norvegicus)
PI3K beta [cytosol] (Rattus norvegicus)
CBL, GRB2, FYN and PI3K p85 subunit are constitutively associated (Rattus norvegicus)
FYN-like kinases:CBL:GRB2:p85-containing Class 1A PI3Ks [cytosol] (Rattus norvegicus)
p85-containing Class 1A PI3Ks [cytosol] (Rattus norvegicus)
PI3K beta [cytosol] (Rattus norvegicus)
p85-containing Class 1A PI3Ks [cytosol] (Rattus norvegicus)
PI3K beta [cytosol] (Rattus norvegicus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
p110 beta [cytosol]
(Rattus norvegicus)
PI3K-regulatory subunits [cytosol]
(Rattus norvegicus)
Participates
as a member of
p85-containing Class 1A PI3Ks [cytosol] (Rattus norvegicus)
PI3K alpha, beta, gamma [cytosol] (Rattus norvegicus)
as an output of
GPVI stimulates PI3K beta, gamma (Rattus norvegicus)
Inferred From
PI3K beta [cytosol]
(Homo sapiens)
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